Excited to share that I will start my lab at the Center for Integrative Genomics in Lausanne @unil.bsky.social in Jan 2027! I’m looking for PhD students fascinated by how cells build tissues and excited about developing new technologies to study development across scales. www.wanlab.bio/pages/9397

Hello all, our lab is recruiting a PhD candidate to study how 3D genome folding impacts gene regulation in development. We're located at the Center for Integrative Genomics department of the University of Lausanne, Switzerland. Please email me if interested. #PhDPosition, #PhDOpportunity

If cell diversity and developmental biology are your thing, my talk will extremely be your jam. Come for the whole-mount spatial transcriptomics and 14Tb light-sheet videos, stay for the humble RNA in situs. Everyone loves in situs 🧪🐟🧅

From fate to form: the journey to whole-embryo spatial transcriptomics! congratulations @yinanwan.bsky.social , so well deserved!!!

very cool method to detect positive selection on regulatory sequences!

🧠 Join us @uzh-ch.bsky.social ! We are a new lab looking for PhDs, Postdocs & Master’s students interested in studying how human neural systems emerge & go awry using brain organoids, light-sheet imaging & genomics. 🚀 Deadline for LSZGS 1st Nov! www.lifescience-graduateschool.uzh.ch/en.html.

Please RP. We are thrilled to announce that our lab’s first preprint is out! ”Whole-genome single-cell multimodal history tracing to reveal cell identity transition” We report HisTrac-seq, a multiomic single-cell molecular recording platform. www.biorxiv.org/content/10.1...

To dissect the gene regulatory networks used to build organisms, we need Perturb-seq-like tools that work in whole animals. For this purpose, we developed MIC-Drop-seq, a tool that couples high-throughput CRISPR in zebrafish embryos with single-cell RNAseq. www.biorxiv.org/content/10.1...

Using a newly developed AI model, the research group @schierlab.bsky.social @biozentrum.unibas.ch @unibasel.ch has discovered in #zebrafish that certain sections of #mRNA control the extent of protein synthesis during early embryonic development. ow.ly/4zyU50V7v1c @cellpress.bsky.social

The Genomic Code: the genome instantiates a generative model of the organism https://www.cell.com/trends/genetics/fulltext/S0168-9525(25)00008-3

Please spread the word: we have @snf-ch.bsky.social -funded #Postdoc and #PhD positions in our lab, to investigate the gene regulatory dynamics during vertebrate skeletogenesis in a comparative setting (see doi.org/10.1101/2024... doi.org/10.1101/2024... ) apply by 31.12.24, start date by 1.2.25!

Out now in Dev Cell! scRNAseq trajectories describe the cascade of gene expression as cells differentiate, but turning them into a clear understanding of the underlying biology of a cell type's development remains challenging. authors.elsevier.com/c/1k9qj5Sx5g... (1/)