The EUROSERPIN2025 meeting, held at the Cloister of San Faustino, University of Brescia, has just ended. Thanks to all participants, speakers, poster presenters and to the University of Brescia. We can't wait for the next EUROSERPIN meeting!

We're welcoming a new cohort of PhD students to the Vienna BioCenter PhD program from various universities around the world. Our Spring call with 25+ fully-funded PhD positions in the life sciences is now open: vbcphd.at @viennabiocenter.bsky.social @vbcscitraining.bsky.social

Tandem duplication of serpin genes yields functional variation and snake venom inhibitors. https://www.biorxiv.org/content/10.1101/2025.01.07.631777v1

Excited to report our studies that identified a new serine protease secreted by the gut microbe Bacteroides fragilis that regulates pain and inflammation through PAR2 activation. #ChemBio. Check it out!https://www.biorxiv.org/content/10.1101/2025.01.15.633241v1

Rare disease research relies on collecting genomic and clinical data across multiple countries. Learn more about the Solve-RD project and how it aims to collect and harmonise #raredisease data across multiple European partners. 🧬🖥️ www.ebi.ac.uk/about/news/a...

We are pleased to announce #EUROSERPIN2025, to be held in Brescia, Italy on May 28-30th 2025! This meeting will bring together international researchers to share their work on all aspects of serpin-related topics. Visit euroserpin.eu to register and submit an abstract.

A bit of microscopy to get me off the mark! Single particle tracking of fluorescent, 20nm spherical protein assemblies (GEMs) as they dance through the ER-lumen of a COS7 cell. One of the tools we used to assess ER-biophysics in α1-antitrypsin deficiency science.org/doi/10.1126/sciadv.abm2094

#Anopheles gambiae SRPN18 crystal structure non-inhibitory serpin @Michel_Lab @IUCr http://scripts.iucr.org/cgi-bin/paper?S2053230X16017854

Unlike other serpins, human serpin B9 shows significant structural deviations around helix D, with a larger surface cavity, which could serve as a promising target for small-molecule inhibitors #Serpins #XRayCrystallography #Crystallization t.co/ilB7Aa3Krg