Excited to share our study out in @natcellbio.nature.com! Led by @mikelangelipid.bsky.social, we identify the first #LipidDroplet lipid quality control pathway: LD-localized FSP1 protects stored lipids from oxidative damage and prevents LD-initiated #ferroptosis. www.nature.com/articles/s41...

I’m happy to share our latest paper on the function of PNPLA3-I148M, the most significant genetic risk factor for fatty liver disease (MASLD). www.cell.com/cell-reports... Many groups have tried to determine the function of PNPLA3 and its disease variant (I148M) since 2008... Thread 🧵 1/5

Looking forward to engaging presentations and discussions at #ASBMB25! I’ll be by poster 270 (Abstract 2651) on Sunday highlighting some of our work on the biological function of the strongest known genetic risk factor for fatty liver disease worldwide, PNPLA3-I148M — stop by if you’re interested

Discovery of a new class of natural antibiotics with a new mode of action to address antimicrobial resistance, a major unmet need @mcmasteruniversity.bsky.social @nature.com www.nature.com/articles/s41...

“Back then, the overwhelming public sentiment was: never again. Today, it seems: never what?”—Siddhartha Mukherjee Exceptional essay Gift link www.nytimes.com/2025/03/10/o...

It's an honor to share this year's Passano Award with Ray Deshaies, Ph.D. for the development of PROTACs, a new therapeutic modality that targets proteins for degradation via co-opting the cellular protein recycling machinery.