@sohailtavazoie.bsky.social
📤 105
📥 37
📝 5
reposted by
The Rockefeller University
6 days ago
Congratulations to all, especially Rockefeller's
@veenapadmanaban.bsky.social
, a research associate in
@sohailtavazoie.bsky.social
's lab, and Maria Cecilia Campos Canesso, formerly a postdoc in
@danmucida.bsky.social
and
@victora.bsky.social
’s labs. A very well-deserved recognition!
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🚨Women with ER(–) breast cancer who took aprepitant (anti-nausea drug, NK1R blocker) had a 31% lower risk of metastasis or death (p<0.001) in large Norwegian study by Botteri & Chang. More doses = better survival 📉.Clinically validates our our work by
@veenapadmanaban.bsky.social
about 1 month ago
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A commonly inherited genetic variant of human PCSK9 drives breast cancer metastasis and associates with reduced patient survival in
@cellcellpress.bsky.social
PCSK9 drives pro-metastatic gene expression by repressing LRP1. Anti-PCSK9 antibody suppresses Br mets.
sciencedirect.com/science/arti...
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A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
Identifying patients at risk for metastatic relapse is a critical medical need. We identified a common missense germline variant in proprotein convert…
https://sciencedirect.com/science/article/pii/S0092867424013266?via%3Dihub……tweetorial
10 months ago
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