Interesting news: The Marine Biological Labs at Woods Hole (MBL) is once again becoming an independent institution. University of Chicago will remain a partner, but only one of many. MBL is an amazing place for science and science training and I hope it will thrive in this new status.

🔔🧪 Super interesting paper from the Sanz-Moreno group showing that the #ECMatrix influences #tumour #dissemination, with distinct #structure in different tumour regions that then affect #invasion patterns. #cancer #metastasis #mechanosensing #mechanoregulation www.nature.com/articles/s41...

NIH-funded research is at risk. Cuts to federal funding could harm science and the economy. Contact Congress now to protect research. Every call matters. Find your reps at govtrack.us and speak up today. #FundScience www.ascb.org/science-poli...

Two great talks today from Chris Ho @chrisho.bsky.social and Julio Belmonte at the UNC MathBio seminar series. Interesting discussions on the role of Coronin 1a and Trim67 interactions in neuron growth cone guidance and the connectivity requirements of local and global cytoskeleton contraction.

🎈New preprint! We study how single cells move up, down and about fibronectin gradients. Experiments by @icfortunato.bsky.social, theory by David Bruckner. Collaboration with @raimonsunyer.bsky.social and @ehannezo.bsky.social 👇https://biorxiv.org/cgi/content/short/2024.12.02.626413v1

🕵🏼1 month ago we published in NatComm new insights on how #CCM vascular lesions are formed by mutated AND healthy ECs. Mutated "convince" healthy to join a lesion via: 💪🏼Forces 🛤️Paths in ECM 🧬Reprogramming #mechanobiology #TFM 👀 See Shapeti et al. here 👇🏼📰 www.nature.com/articles/s41...

Just out! Exploring the Impact of Variability in Cell Segmentation and Tracking Approaches. Published in Microscopy Research and Technique. Thanks #BBSRC for funding. see: doi.org/10.1002/jemt... @laurawiggins13.bsky.social @globias.bsky.social @eurobioimaging.bsky.social

Total articles have grown exponentially in the last few years. Academics know this, cause they're sick and tired of requests to review, or submit their 'preeminent paper' to journal "justmadeup" - for a fee of course. What's striking is how this has grown disproportionate to no. of scientists 🧵 2/n

Traction force microscopy is important tool for #mechanobiology! Check our thread for some of the historic papers moving the technique forward!

Q: What's wrong with these plots? A: Pooling cell-level measurements across multiple runs conceals experimental reproducibility. Read more in JCB (with @fritzlaylin.bsky.social @katrinavelle.bsky.social & Dyche Mullins): rupress.org/jcb/article/...

Hi #cancer, #ECMatrix, #biomaterials and #mechanobiology folks: Below a Nat Cell Biol paper from the Chen and Weaver groups, of interest to many of us 🧪👇: www.nature.com/articles/s41...

Chromatin compaction during confined cell migration induces and reshapes nuclear condensates. doi.org/10.1038/s414...

Cell response to extracellular matrix viscous energy dissipation outweighs high-rigidity sensing www.science.org/doi/10.1126/...

Something we’ve been working on recently: soft PDMS micropatterned channels for traction force microscopy during confined migration. If you’re interested in seeing cells crawl through them while we measure traction forces take a look at our recent preprint! www.biorxiv.org/content/10.1...

Thought this would be a great opportunity to gather the #mechanobiology community. Please feel free to spread the word. go.bsky.app/G5cQqYT

Introducing "3D Micropatterned Traction Force Microscopy", our new joint work with Pere Roca-Cusach's lab, led by amazing Laura Faure and Manu Gómez. Hope you find it useful!👇 onlinelibrary.wiley.com/doi/full/10....