Powerful piece in STAT this morning from some NIH staff members who have resigned www.statnews.com/2026/01/10/n... 1/3

Out now!! www.nature.com/articles/s44... Intro to this paper pictured below Huge thanks to collaborators @neilmdavies.bsky.social, @emmylooroll.bsky.social at @uclbrainscience.bsky.social & Sami Heikkinen and Mikko Hiltunen at @uniuef.bsky.social ... #endalz #episky #medsky

NOTE: This news immediately followed a Supreme Court order this morning denying the paper's shadow-docket efforts to block an injunction issued by the Third Circuit that was enforcing an NLRB unfair labor practices order relating to the paper's health insurance plans.

I'm starting a thread on misunderstandings about the role of APOE in Alzheimer's disease / dementia, from the POV of epidemiology / statistical genetics. I will add to this sporadically over time... #endalz #episky #medsky

More news (not good) from NIH The renewal request from National Institute of Neurological Diseases and Stroke Director Walter Koroshetz has been denied. I guess the NIH_leadership™ needed another position to fill with their time-tested recruitment process.

The Senate version of the NIH appropriations bill has language that limits the use of multiyear/upfront funding. Please call your Senators and Representatives to make sure it is in the final bill. We must stop the brain drain in our research workforce before it's too late.

This substantial drop in studies funded is the abrupt transition to multiyear/upfront funding at work. This policy is incredibly damaging to the scientific workforce. It is driving people out of science, especially the next generation of researchers.

Glad to see Congress doing some oversight of new NIH policies. www.congress.gov/crs-product/... Number of new awards is way down since Trump took office, despite NIH spending the same amount of money.

Lifesaving research: gutted. Vaccines: restricted. Science: ignored. Enough is enough. RFK Jr. must be removed from office.

SBIR/STTR Program still at a standstill... www.nsbaadvocate.org/post/news-sb...

A lot of NOFOs at #NIH have expired. If you wish to submit an unsolicited application, do so to the parent #NOFO. Furthermore, unsolicited applications no longer require prior approval for exceeding $500K. Please inform your networks. #geronsky #hspr #hpss #statssky

The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine www.nytimes.com/interactive/...

For those of you attending #GSA2025 in Boston, consider this panel of #NIH awardees, Drs. Alden Gross, @mariaglymour.bsky.social , @sfackley.bsky.social , and @bryandjames.bsky.social. Please remember to tag #geronsky and @geronsociety.bsky.social in your posts.

Well reported story on the PBS News Hour about science cuts and the ongoing and potential brain drain. www.youtube.com/watch?v=yLvO... Thanks to Terrance Tao and other scientists at various career stages for having the courage to speak out. Watch and share! 1/7

Happy Sinkhole Bus day to yinz who celebrate!

Lego MRI scanner set (donated to hospitals) a big help for kids who need scans: "more than 1 million children globally have used the sets to help them prepare...96% of healthcare professionals said the model helps to reduce children's anxiety, and 46% reported a lesser need to use sedation"

I am here for the region-specific insults. No Kings Pittsburgh.

My sign.

No Kings-Austin,TX

Hell yes, Pittsburgh. Love Yinz. No Kings.

The local PGH flavor today included a «Won’t You Be My Neighbor » singalong #NoKings

Things are at a standstill with the govt shutdown, the year has been one of 'constant chaos' at the NIH — & the worst may be yet to come folks said on my panel Read a recap of our talk w/ @jeremymberg.bsky.social @malar0ne.bsky.social & Eric Green here www.statnews.com/2025/10/16/f...

I have been trying to get this published as an op-ed, but I am going to post it here since I think it is timely in light of the "consent" extortion events. Deafening Quiet from the Scientific Establishment jeremymberg.github.io/jeremyberg.g... 1/14

This moment from our latest episode with science writer @edyong209.bsky.social is 🔥 We asked Ed — how do we talk up the benefits of science in the face of government cuts? He told us that's the wrong approach. 🧪 Listen wherever, or watch on Spotify 👇 open.spotify.com/episode/7Evh...

One of the important consequences of early detection of cancer... (From this past weekend, 11 years and 3 months after her breast cancer detection)

Check out this great article from @sciam.bsky.social on racial disparities in Alzheimer's disease. Researchers should include historically minoritized communities in studies of these new frontiers in dementia diagnosis and treatment, says epidemiologist Beth Shaaban of the University of Pittsburgh.

So... I did some analysis of grants that did receive noncompetitive renewals. In particular, I looked a those award where the title of the grant changed. Warning: The results are just what I expected, but oooph... 1/4

Full resignation letter from Demetre C. Daskalakis, a CDC leader, does not hold back. "The recent shooting at CDC is not why I am resigning. My grandfather, who I am named after, stood up to fascist forces in Greece and lost his life doing so. I am resigning to make him and his legacy proud."

Alzheimer’s & Dementia Call for Papers: Waking Up to the Importance of Sleep in Alzheimer's Disease and Related Dementias ✦ Mechanisms of circadian disruption ✦ Digital sleep biomarkers and more #ALZResearch ⏰Deadline: Oct. 31, 2025 alz-journals.onlinelibrary.wiley.com/hub/journal/...

Call For Papers! Alzheimer's & Dementia Special Issue: Neuromodulatory Subcortical Systems in Alzheimer's Disease Research on the intersection of the Neuromodulatory Subcortical Systems and AD are welcome! #AlzResearch ⏰Deadline: Aug. 30, 2025 alz-journals.onlinelibrary.wiley.com/hub/journal/...

Emergency Department (ED) staff: screen ALL patients over 65 for delirium. Emergency departments are where it's most missed and most dangerous. Make it as routine as checking blood pressure.

Here is the Science story on the "priorities" memo... www.science.org/content/arti...

New Guardian article about the Bhattacharya op-ed www.theguardian.com/us-news/2025... 1/4

This is a great annotated thread of the new EO to help understand what it is attempting to do.

One more effort to politicize federal grantmaking. *Grants must by approved by a political appointee, working with OMB. *"Discretionary awards must, where applicable, demonstrably advance the President’s policy priorities." *Cannot "promote anti-American values" www.whitehouse.gov/presidential...

Well, this is a huge Executive Order power grab... www.whitehouse.gov/presidential... 1/3

Thanks @murray.senate.gov and the Appropriations committee for the bipartisan bill that rejects the draconian cuts to NIH science and restricts the harmful multiyear funding scheme! www.appropriations.senate.gov/news/minorit...

🏆 Donna M. Wilcock, Ph.D., is the recipient of the 2025 Bill Thies Award for Distinguished Service to ISTAART. This award recognizes an @istaart.bsky.social member who has provided continued and outstanding service to the ISTAART community. @wilcocklab.bsky.social @iusm-medneuro.bsky.social

Make sure to check out these poster presentations featuring @naccdata.org authors today at #AAIC2025!

Check out the great research posters being presented by #NIAfundedADRC REC Scholars today at #AAIC2025! Learn more about the Research, Education, Component (REC): naccdata.org/adrc-resourc...

@mariacarrilloalz.bsky.social shares exciting #AAIC25 attendee stats: 🔬 Nearly 8,200 are in Toronto & 3,200+ are online 🔬48% of in-person attendees & 61% of virtual attendees are women 🔬 23% are under age 35 🔬 More than 22% are first-time attendees 🔬More than 70% are @istaart.bsky.social members

This is fun. Watching your first ever mentor in science give the plenary at AAIC. I was Katerina’s first technician, helping out with her 2002 mouse studies shown on this slide. Haven’t met a more tenacious scientist since. To see a single hypothesis all the way through to clinical trials is amazing

Takeaways from U.S. POINTER top line results: ➡️ Both a structured & a self-guided intervention improved cognition, with the structured group improving even more. ➡️ Cognitive benefits were consistent across age, sex, ethnicity, heart health status and APOE e4 genotype. bit.ly/USPointerRel... #AAIC25

#PopNeurosciCollab at #AAIC25! *A fun meeting w/ @leadcoalition.bsky.social *Mtg new folks interested in joining the Diversity and Disparities PIA while tabling @ PIA Day *Daniel Willie-Permor (Aβ/tau resistance/resilience) & Ale Ramirez-Tirado (peripheral & central inflammation) posters @ AIC

A&D Journal Events at #AAIC25- Monday July 28 ☑️ Meet the Editors- #BSEA Editor Jennifer Lingler @jlingler.bsky.social (10:30am) ☑️ Meet the Editors- #TRCI Editor Tim Hohman (12:30pm) 📍@alzassociation.bsky.social booth ☑️ Peer Review Workshop with Editors of A&D Journals (12:30pm) 📍 Room 603

For #AAIC2025 attendees: #ADRD researcher starter pack! Thanks @tyk314.net for promoting me to share this again go.bsky.app/22DpUEy

🏆 Mary Sano, Ph.D., is the recipient of the Bengt Winblad Lifetime Achievement Award. Dr. Sano is a neuropsychologist by training and an award-winning clinical trialist, focusing on cognitive impairment in aging, Alzheimer’s and related dementias. #AAIC25

🧠 TIME-AD is now on Bluesky! #TIME-AD brings together results from different study designs and populations to find what really works to prevent and delay dementia. Follow along as we share what we’re learning and check out our website to learn more: www.time-ad.org #EndALZ #EpiSky #NeuroSky