Drug Discovery Unit, University of Dundee
@ddu-dundee.bsky.social
📤 343
📥 523
📝 39
Science is pretty! Seems like a great time to find out about the incredible impact that
#HenriettaLacks
had on modern science!
add a skeleton here at some point
2 months ago
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Drug Discovery Unit, University of Dundee
Manu De Rycker
2 months ago
Hot off the press: our Target Product Profile to support the development of new medicines to treat
#cryptococcal
disease:
www.sciencedirect.com/science/arti...
#cryptococcus
,
#drugdiscovery
,
#meningitis
@ddu-dundee.bsky.social
,
@gsk.bsky.social
,
@dndi.org
and many others 🧪
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Target product profile and discovery and development path for novel cryptococcal disease treatments
Cryptococcus neoformans and Cryptococcus gattii are World Health Organization critical and medium priority pathogens, respectively. These mainly impac…
https://www.sciencedirect.com/science/article/pii/S0163445325002439
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Good morning sky-friends! We have exciting news today! Our head of biology Dr
@mdr-ddu.bsky.social
has been awarded the WH Pierce Global Impact in Microbiology Prize by
@amiposts.bsky.social
as part of their International Horizon Awards
drugdiscovery.dundee.ac.uk/news/dr-manu...
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Drug Discovery Unit - Dr Manu De Rycker recognised with global honour
Dr Manu De Rycker has been named as the newest winner of the WH Pierce Global Impact in Microbiology Prize.
https://drugdiscovery.dundee.ac.uk/news/dr-manu-de-rycker-recognised-with-global-honour
2 months ago
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reposted by
Drug Discovery Unit, University of Dundee
Manu De Rycker
4 months ago
#Chagas
disease remains very neglected, and not only in the US, in spite of an estimated 8 million people being infected with T. cruzi. We, and our collaborators, aim to develop new medicines, but this is becoming increasingly challenging due to lack of funding.
www.theguardian.com/us-news/2025...
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‘Kissing bug’ disease should be treated as endemic in US, scientists say
People in at least eight states have been infected with Chagas, new report says, amid low awareness of disease
https://www.theguardian.com/us-news/2025/sep/13/kissing-bug-chagas-disease
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Drug Discovery Unit, University of Dundee
UNLEASH
4 months ago
Good morning Bluesky! We have reached the end of our UNLEASH meeting and are all preparing to head home. We are full of enthusiasm and renewed purpose, and we look forward to keeping you all updated on our work! Tell us - what do you want to know about us?
#SciComm
#RNA
#Splicing
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Good morning Sky-Friends! Our own
@biochemtrix.bsky.social
(and occasional poster!) is in Germany at the
#Unleash
consortium meeting. They are joining us here in the sky
@unleash-as.bsky.social
so follow along to find out about
#AlternativeSplicing
!
4 months ago
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reposted by
Drug Discovery Unit, University of Dundee
Manu De Rycker
4 months ago
Great opportunity to join our multi-partner collaboration to develop much needed new
#antifungal
drugs!
#jobs
,
#drugdiscovery
,
#Cryptococcus
,
#Candida
@mrccmm.bsky.social
@ddu-dundee.bsky.social
@labwyllie.bsky.social
@glaxosmithkline.bsky.social
add a skeleton here at some point
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reposted by
Drug Discovery Unit, University of Dundee
Manu De Rycker
6 months ago
Delighted to announce a £17.9 million award from
@wellcometrust.bsky.social
for the development of new antifungal treatments to a consortium of
@ddu-dundee.bsky.social
,
@labwyllie.bsky.social
,
@mrccmm.bsky.social
and GSK.
#Cryptococcus
#Candida
#drugdiscovery
#antifungal
🧪
tinyurl.com/wywtkpsx
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£17.9m research grant to discover new treatments for fungal diseases
A team of leading infectious disease scientists from academia and industry have been awarded £17.9 million to identify new drugs to treat fungal infections
https://tinyurl.com/wywtkpsx
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reposted by
Drug Discovery Unit, University of Dundee
Manu De Rycker
6 months ago
Great to have a latest
#Chagas
disease drug discovery paper published in
@rsc.org
MedChem:
pubs.rsc.org/en/content/a...
This work highlights how we decide to progress or terminate series, and hopefully provides some useful approaches and lessons.
@ddu-dundee.bsky.social
🧪
#NTD
#drugdiscovery
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Structure–activity relationships of 1,5-dihydro-2H-benzo[b][1,4]diazepine-2,4(3H)-diones as inhibitors of Trypanosoma cruzi
Chagas disease, caused by infection with the protozoan parasite Trypanosoma cruzi (T. cruzi), is responsible for a large health burden with around 6–8 million people infected globally. The current dru...
https://pubs.rsc.org/en/content/articlelanding/2025/md/d5md00185d
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reposted by
Drug Discovery Unit, University of Dundee
The Women In Science Archive
6 months ago
Nuclear physics pioneer Harriet Brooks was born OTD 149 years ago. The discoverer of Nuclear Recoil, the transmutation of elements through radioactivity, and nuclear series, her productive career was brought short by marriage. Here is her story
tinyurl.com/mvcd3ape
#WomenInSTEM
#Physics
#HistSci
🧪
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Wither: The Many Triumphs and Long Fall of Nuclear Physicist Harriet Brooks.
Reading the life of Harriet Brooks is like watching the gradual, inevitable unfolding of a horror movie. There's that same idyllic, promising beginning that suddenly gives way as the heroine puts her...
https://tinyurl.com/mvcd3ape
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reposted by
Drug Discovery Unit, University of Dundee
Peter Kenny
6 months ago
Opportunity for computational chemist at Syngenta (Stein Switzerland)
#CompChem
#cheminformatics
#ML
#AI
#agrochem
#ChemJobs
#chemsky
🧪
jobs.syngenta.com/job/principa...
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Principal Scientist - Computational Chemistry (m/f/d)
https://jobs.syngenta.com/job/principal-scientist-computational-chemistry-m-f-d-in-ch-stein-jid-13737
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reposted by
Drug Discovery Unit, University of Dundee
Dundee City Archives
6 months ago
Another mystery
#WhereisitWednesday
picture for you all. Taken probably in the 1920s, this seems to be a road in Broughty Ferry, or possibly towards Monifieth. But aren't sure where it is. Do you have any ideas?
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reposted by
Drug Discovery Unit, University of Dundee
Nature
6 months ago
A genetic modification that causes mice to overexpress a particular hormone prevents them from gaining weight and allows them to live longer
https://go.nature.com/4l3rWk2
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Hormone helps mice live longer and avoid obesity
Male mice that make high levels of fibroblast growth factor 21 stay lean as they age — a finding that could translate to humans.
https://go.nature.com/4k84CQQ
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reposted by
Drug Discovery Unit, University of Dundee
Nature
7 months ago
We're gonna need a bigger boat 🦈
https://go.nature.com/463XAch
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Happy birthday Jaws! How the movie changed shark science
Half a century after its cinematic release, Jaws is still shaping how we view — and protect — the ocean’s top predators.
https://go.nature.com/4lilUM8
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reposted by
Drug Discovery Unit, University of Dundee
University of Southampton
7 months ago
50 years on from the release of movie blockbuster Jaws, our shark expert @thesimslab.bsky.social @sotonoceanearth.bsky.social debates the so called 'Jaws effect', charting the fortunes of the 'great white' for @theconversation.com. Read more 👉
https://tr.ee/5gCSPz
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Jaws helped spur a fishing frenzy – so how have the world’s sharks fared since the 1975 release?
The film made us afraid to go back in the water. It ultimately gave sharks more to fear from us.
https://tr.ee/5gCSPz
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reposted by
Drug Discovery Unit, University of Dundee
Royal Society of Chemistry
7 months ago
If you’re studying chemistry & anything about graduating is making you anxious – whether that’s finding a job, managing finances, or feeling generally overwhelmed – we’re here for you. ➡️8am – 8pm, Mon–Fri: call 0800 084 3451 (UK Freephone) or +44 1223 853549 (Intl):
buff.ly/tCWlE7s
#ChemSky
#EduSky
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reposted by
Drug Discovery Unit, University of Dundee
Protein Data Bank in Europe (PDBe)
7 months ago
🧪 We're beta testing - and we want your thoughts! Try the redesigned PDBe entry pages & let us know: 🔸 What’s working? 🔸 What’s confusing? 🔸 What features do you miss? 💬 Feedback form:
tinyurl.com/pdbe-beta-form
#PDBeBeta
#Bioinformatics
#Biochemistry
#Science
#UserVoice
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reposted by
Drug Discovery Unit, University of Dundee
PLOS Biology
7 months ago
Despite a century of use in
#DrugDiscovery
, specialized metabolism continues to amaze. Justin Nodwell explores a
@plosbiology.org
study that uses a novel computational approach to uncover unsuspected functions of a compound produced by
#Streptomyces
🧪 Paper:
plos.io/43UVUPB
Primer:
plos.io/4n25bOF
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reposted by
Drug Discovery Unit, University of Dundee
Cristina Pujades
7 months ago
Do you want to join us to work in neurodevelopmental biology? Please apply 👇
#SEBD
0
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reposted by
Drug Discovery Unit, University of Dundee
C&EN (Chemical & Engineering News)
7 months ago
Nominate a chemist with disabilities for C&EN's Trailblazers 2025! Please tell us about your chemistry heroes, mentors, mentees, and inspirations—or nominate yourself. 👉
cenm.ag/nominatetrai...
#chemsky
🧪
#phdsky
#academicsky
#STEM
#phdchat
#academicchatter
0
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reposted by
Drug Discovery Unit, University of Dundee
Nature Reviews Drug Discovery
7 months ago
For readers interested in ion channels as drug targets, this Review in the May issue focuses on voltage-gated sodium channels, such as Nav1.8, the target of the first new non-opioid analgesic to be approved in decades
www.nature.com/articles/s41...
rdcu.be/enkq4
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reposted by
Drug Discovery Unit, University of Dundee
Institute of Molecular Genetics
8 months ago
🧬 Passionate about primary cilia and cell signalling? 🧫 Curious about the actin role in growth and function? 🗣️ Skilled in communication and value flexibility in your work? Join IMG now! ➡
www.img.cas.cz/2025/05/8654...
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reposted by
Drug Discovery Unit, University of Dundee
Barbara Pernaute
8 months ago
🚨🚨#Hiring! 3 year
#postdoc
position open in my lab
@cabd-upo-csic.bsky.social
to study the interplay between DNA damage responses and
#preimplantation
embryo development. Fully funded by EARLYFATE
#ERCCoG
📆 Apply by 23rd May 2023 🔗Details below
@sebioldev.bsky.social
Please RT!🙏
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Morning sky friends! Check out this LinkedIn post from our friends
@astrazeneca.bsky.social
's Cambridge Discovery Centre! Dr Luma Godoy Magalhaes is spending some time away from us in sunny Dundee to start work on the first
#MRC
funded
#HTS
project.
#collaboration
www.linkedin.com/posts/hannah...
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Launching the first Medical Research Council (MRC) funded High Throughput… | Hannah Semple
Launching the first Medical Research Council (MRC) funded High Throughput Screen (HTS) in AstraZeneca's Cambridge Discovery Centre! As part of AstraZeneca Open Innovation, we offer access to our ...
https://www.linkedin.com/posts/hannah-semple_launching-the-first-medical-research-council-activity-7328400100274192384-5cu6?utm_source=share&utm_medium=member_desktop&rcm=ACoAAA8GY08BdHAAYZ3A966bZjeWo7e8C-E5N28
8 months ago
0
2
0
reposted by
Drug Discovery Unit, University of Dundee
UNAIDS Global
8 months ago
The cuts in US funding continue to impact countries. Read how HIV services and communities in Angola, Lao PDR, Lesotho, and South Africa are being impacted, and how governments and partners are taking urgent action protect progress and ensure continuity of care.
www.unaids.org/en/impact-US...
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reposted by
Drug Discovery Unit, University of Dundee
The Institute of Cancer Research
9 months ago
The Telegraph recently shared an obituary of our former Chief Executive, Professor Peter Garland, who was both a highly successful academic and leader.
www.telegraph.co.uk/obituaries/2...
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Peter Garland, biochemist who led the Institute of Cancer Research as it made vital new discoveries
He played a key role in the development of Humira – for rheumatoid arthritis and Crohn’s disease – which become a top-selling medicine
https://www.telegraph.co.uk/obituaries/2025/04/13/professor-peter-garland-dundee-university-cancer-adalimumab/
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reposted by
Drug Discovery Unit, University of Dundee
PLOS Biology
9 months ago
Our latest editorial in defense of vaccines and vaccination, introduces two Perspectives in this issue on priorities for outbreak vaccination, as well as the important successes of vaccines to date Please read and spread the word 🙏🏻!
add a skeleton here at some point
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reposted by
Drug Discovery Unit, University of Dundee
Martin Loose
9 months ago
Looking for a student or postdoc! Want to combine evolutionary analysis + structural modeling with in vitro biochemistry & fluorescence microscopy? Help us uncover new protein-protein interactions — from in silico to in vitro. Join us at
@istaresearch.bsky.social
👉
looselab.org
🧬💡🔬🎡
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https://looselab.org
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Good morning sky pals! Here's a good read for your morning coffee: Navigating the Landscape of Academic
#DrugDiscovery
: An 18-Year Journey, written by our very own Dr Beatriz Baragana & Dr Laura Cleghorn for
@acs.org
pubs.acs.org/doi/full/10....
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Navigating the Landscape of Academic Drug Discovery: An 18-Year Journey
https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.5c00885
9 months ago
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reposted by
Drug Discovery Unit, University of Dundee
Wellcome Connecting Science Learning and Training
9 months ago
Join us in person for our
#MetabolicMultiomics25
conference! Explore the application of powerful
#omics
tools for studying
#MetabolicDiseases
& cancer. Discover the potential for new clinical treatments at the intersection of research & translational medicine. Register by 6 May 📎
bit.ly/3DF6vET
0
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reposted by
Drug Discovery Unit, University of Dundee
WHO
9 months ago
It's
#WorldHealthDay
Since 2000, maternal deaths globally declined by 40%! 💙 BUT—progress is slowing, and aid funding cuts mean major threats to lifesaving maternity services in many parts of the world. ❌
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Drug Discovery Unit, University of Dundee
Manu De Rycker
9 months ago
Happy to announce that today we start a new
#Chagas
drug discovery project, funded by MRC
@ukri.org
. In this project we will be carrying out lead optimisation on a series of squalene synthase inhibitors. More info at:
gtr.ukri.org/projects?ref...
🧪
@ddu-dundee.bsky.social
#UniversityOfDundee
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Gateway to Research (GtR) - Explore publicly funded research
The Gateway to Research: UKRI portal onto publically funded research
https://gtr.ukri.org/projects?ref=MR%2FZ505377%2F1
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Drug Discovery Unit, University of Dundee
Royal Society of Chemistry
9 months ago
We are set up and ready today’s Inclusion and Diversity Forum 🎉 A day filled with talks, presentations, discussions and networking both online and in person.
#Equality
#Diversity
#Inclusion
#ChemSky
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reposted by
Drug Discovery Unit, University of Dundee
Chemistry World
9 months ago
Are you seeking a powerful statistical methodology when planning your experimental work? Day 1 of our free two-day webinar series on design of experiments with JMP is starting now! Sign up to learn how DoE might be just what you're looking for:
attendee.gotowebinar.com/register/219...
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Good morning sky-pals! It's the start of
#NeurodiversityCelebrationWeek
and on campus we have lots of events - check them out here!
www.dundee.ac.uk/campaigns/ne...
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Neurodiversity Celebration Week
17 March 2025 – 23 March 2025
https://www.dundee.ac.uk/campaigns/neurodiversity-celebration-week
10 months ago
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reposted by
Drug Discovery Unit, University of Dundee
Peter Kenny
10 months ago
Opportunity for
#cheminformatics
data scientist at Drug Hunter (USA remote)
#DataScience
#CompChem
#ChemJobs
#chemsky
🧪
drughunter.isolvedhire.com/jobs/1444460
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Cheminformatics Data Scientist -
Drug Hunter™ (drughunter.com) is an essential web-based knowledge platform for drug discovery and development innovators turning molecules into medicines. The Scientific team at Drug Hunter™ distills ...
https://drughunter.isolvedhire.com/jobs/1444460
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Drug Discovery Unit, University of Dundee
WHO
10 months ago
Violence against women demands urgent attention. One in three women faces physical or sexual violence, and nearly 25% of workplace violence happens in hospitals or clinics — and women are most affected.
#BeijingPlus30
#IWD2025
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Drug Discovery Unit, University of Dundee
Drugs for Neglected Diseases initiative (DNDi)
10 months ago
We support the
#StandUpForScience
movement today! 🔬 Protecting scientific integrity and evidence-based decisions are crucial for a better future. Scientific progress is a common good we must defend.
#standupforscience2025
#sciencenotsilence
#scienceforall
👉
standupforscience2025.org/local-event-...
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Local SUFS Events
Stand Up for Science is officially supporting rallies in Washington DC and 31 other cities around the country. This means that a confirmed site leader—backed by our core team—is actively organizing…
https://standupforscience2025.org/local-event-information/
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Come work with us! An opportunity is available within our
#TB
portfolio as a
#DrugDiscovery
#Biology
coordinator. See the attached link for further details and for contact information for informal enquiries.
#BiologyJobs
www.dundee.ac.uk/work-for-us/...
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Drug Discovery Biology Coordinator - UOD1860
Closing date: Thursday 3 April 2025, 23:59
https://www.dundee.ac.uk/work-for-us/jobs/uod1860
10 months ago
0
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Drug Discovery Unit, University of Dundee
WHO
10 months ago
Today is
#WorldObesityDay
.
#Obesity
is a complex condition and each individual faces distinct needs & challenges. A healthier society is possible only if we prioritize community support & stand up against discrimination and stigma 🔗bit.ly/3SAcdeE
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For those who are supporting or supervising staff or students who maybe celebrating
#Ramadan
this month, or if you are just interested in finding out more, the Muslim Council of Britain
@muslimcouncil.bsky.social
have this helpful guide.
mcb.org.uk/wp-content/u...
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https://mcb.org.uk/wp-content/uploads/2025/02/MCB-Ramadan-2025-Guide.pdf-2.pdf
10 months ago
0
0
0
reposted by
Drug Discovery Unit, University of Dundee
Royal Society of Chemistry
10 months ago
We're almost there! 🙌 Tomorrow, the
#RSCPoster
competition will start on LinkedIn. If you haven't already, then please register before midnight TODAY (UK
time) ➡️ buff.ly/ZKw4l9j We lo
ok forward to seeing all your posters!
#ChemSky
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Drug Discovery Unit, University of Dundee
V&A Dundee
10 months ago
📣 We’re so excited to announce our upcoming exhibitions and displays! 📣 With FIVE free displays to enjoy and our next major exhibition
#VADGardenFutures
opening in May (tickets on sale now!), take a look at what’s coming up this year at the museum 👇 Find out more:
va.scot/3D5iETU
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Now & Next: What's on in 2025
Tickets for Garden Futures now on sale, plus five new free shows
https://va.scot/3D5iETU
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Good morning sky friends! A very blessed Ramadan to all who are celebrating.
10 months ago
1
1
0
reposted by
Drug Discovery Unit, University of Dundee
Peter Kenny
10 months ago
#PostDoc
opportunity in X-ray
#crystallography
at Institute for Cancer Research (Sutton UK) duration: 2 years | closing: 16-Mar-2025
#StructBiol
#oncology
#PostDocJobs
🧪
jobs.icr.ac.uk/vacancies/11...
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Postdoctoral Training Fellow – X-Ray Crystallography in Sutton | The Institute of Cancer Research
View details and apply for this Postdoctoral Training Fellow – X-Ray Crystallography vacancy in Sutton. Salary: Dependent on relevant Postdoctoral experience. Future progression is base...
https://jobs.icr.ac.uk/vacancies/1130/postdoctoral-training-fellow--x-ray-crystallography.html
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reposted by
Drug Discovery Unit, University of Dundee
Wellcome Connecting Science Learning and Training
10 months ago
🌟 Contribute to therapeutic advances to treat metabolic disease If you're working with
#omics
tools and technologies to gain deeper insights into
#MetabolicDisease
, we'd love you to present at
#MetabolicMultiomics25
Submit your abstract by 18 March⏰ 🗣️Join a stellar speaker line-up 📎bit.ly/3DF6vET
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reposted by
Drug Discovery Unit, University of Dundee
Drugs for Neglected Diseases initiative (DNDi)
11 months ago
👀 In case you missed it...here’s a sneak peek into Guinea’s incredible journey to eliminate
#SleepingSickness
as a public health problem! 📽️ Watch the full film to see how Guinea achieved this milestone:
youtube.com/watch?v=csdn...
#BeatNTDs
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reposted by
Drug Discovery Unit, University of Dundee
Universities Scotland
11 months ago
Join us this Saturday morning at the
@scottishlabour.bsky.social
Conference where we will be discussing the essential role universities play in the provision of high-level education, skills, and experience to support our existing and next generation workforce.
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Happy Friday, Sky-Friends! Hope your week has been productive and full of science, and you can look forward to a restful weekend!
11 months ago
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reposted by
Drug Discovery Unit, University of Dundee
Drugs for Neglected Diseases initiative (DNDi)
11 months ago
👋 We are excited to welcome our two newest DNDi North America Board Members: 🔸 Bethany Hills Grois, Partner at White & Case LLP 🔸 Jeff Nelson, Chief Operating Officer at Milestone Pharmaceuticals, Inc. 👉 Learn more about their impressive backgrounds here:
dndina.org/about/
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About
DNDi is an international, non-profit R&D organization. We discover, develop, and deliver affordable treatments for neglected patients – saving millions of lives, globally.
https://dndina.org/about/
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