One-month treatment for latent tuberculosis. Why aren't we using it? (Hint: We should.) voices.nejm.org/doi/full/10....

Man from 🇭🇹 Unilateral scrotal swelling (+/- painless) To be continued #IDsky …

Wow! What a game @wrexhamafc.co.uk ❤️❤️ Champagne !

Wrexham vs Chelsea 5th round FA cup 1-0 1-1 (own goal) 2-1 2-2 2-3 (Red card Wrexham) 3-3 (off side) 2-4 final Honestly, f*** yes Wrexham ❤️❤️❤️ Now, let’s go back to Championship playoff race. 11 fixtures We are at position #6 Hull city (#5) Tuesday Swansea city (#14) Friday … Let’s go! #askwxm

❤️ @wrexhamafc.co.uk

Omadacycline Monotherapy in NTM Pulmonary Disease Caused by Mycobacterium abscessus: Results From a Phase 2, Double-blind, Randomized, Placebo-controlled Study Compared to placebo, omadacycline monotherapy led to higher response rates Note: Lung Tx excluded academic.oup.com/cid/advance-... #IDSky

Madrid vacation with my family Wrexham ❤️ @wrexhamafc.co.uk #everytime #anywhere for Gab, 7 yo

The just published TAPER-V trial has lots of fun journal club things to discuss: jamanetwork.com/journals/jam...

🔥Just published 🔥 TAPER-V RCT In this RCT of 256, a 4-week vancomycin pulse and taper regimen *had a probability of 74% to be superior to a standard 2-week pulse regimen in patients a first episode or first recurrence of CDI Vanco for 10d is obsolete! #IDSky #EMIMCC jamanetwork.com/journals/jam...

Lenacapavir for PrEP was the big "star" of #CROI2026 after showing almost 100% effectiveness in preventing HIV in 2 large RCTs. Unfortunately at a pricing point of 28000$ a year it remains inaccessible to most. A drug is only as great as the number of people who can access and benefit from it.

That’s a wrap from #CROI2026. Until next year in hopefully warm & sunny San Diego! But my writing has only just begun — look for reports on @pozmagazine.bsky.social & @aidsmap.bsky.social in coming days.

Meningococcal B (4CMenB) Vaccination for the Prevention of Gonorrhea in Men Who Have Sex With Men #CROI2026 credits @ hivvirology

🤨Comparative Effectiveness of 3 Benzathine Penicillin G-Based Regimens in PWH With Early Syphilis #CROI2026 credits @ hivvirology

Best place to follow #CROI2026 on social media👇 www.instagram.com/hivvirology/

🔥Just published 🔥 ESCMID Clinical Guidelines on the Evaluation and Management of a Reported Antibiotic Allergy #IDSjy www.clinicalmicrobiologyandinfection.org/article/S119...

#IDSky I always email residents rotating with me survival tips for their time of the ID consult service. I like to keep this short and high yield but I am constantly editing and improving the tip sheet. What would you add or remove. It cannot be longer that one page 😊.

When I am declared God King Emperor, I am banning Cdiff PCR's

My top 10 ID papers for 2025. Full citations and descriptions available at clarityinitiative.org/hot-takes Also see/hear our Communicable podcast episode on this at communicable.transistor.fm/episodes/com... What were your top 10? Any thoughts about what I missed welcome! #IDSky #Top10papers

Grateful to have the opportunity to share this little piece of my heart. Love is always the answer. academic.oup.com/cid/advance-...

I highly recommend @patrickching.bsky.social latest commentary in @ashejournal.bsky.social describing: -the history of contact precautions -the need for balance ⚖️ between the benefits of gowns/gloves with their cost/environmental impact www.cambridge.org/core/journal... #IDSky

Finally, a mainstream media article on a subject many of we infectious disease docs have to deal with on an almost daily basis. It correctly identifies a “wellness” industry profit motive that drives the misinformation on this subject. www.cbc.ca/news/investi...

Browse the best of 2025! The Editors-in-Chief of cidjournal.bsky.social, jidjournal.bsky.social & ofidjournal.bsky.social have selected a collection of outstanding articles from 2025. Explore research on long COVID, AMR, HIV, influenza, vaccines & more: https://bit.ly/49Xgge6 paulsaxmd.bsky.social

Subcutaneous antibiotic administration is increasingly recognized as a valuable alternative to intravenous therapy in selected clinical contexts. In CID, authors summarize current clinical experience, PK/PD data, and technical aspects of subcutaneous infusion. https://bit.ly/3NB1jH5

OI YOU … Podcast on Azole Antifungals. Would be a shame if you reposted it to AAAAAAALLL your followers, and liked it and commented on what you thought of it below PLEASE DON’T DO THAT we hate popularity!! #IDsky #microsky #fungi podcasts.apple.com/gb/podcast/i...

🧵 Essential ID Papers for 2025: A Clinician’s Guide Each year brings a flood of amazing ID literature. Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines. 👇

Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis Congratulations to David Meya, Fiona Cresswell, @natebahrid.bsky.social @drboulware.bsky.social & co on this important trial No mortality benefit to high dose rifampin in adults with TB meningitis www.nejm.org/doi/full/10....

🆕⚡🧠HARVEST TRIAL:More Rifampin,Same Fate: High-Dose Rifampin Fails to Shift the Needle in TB Meningitis,NEJM,2025 Despite better theoretical CNS penetration,high-dose oral rifampin did not improve survival in adult TB meningitis & potential harm cannot be excluded #idsky www.nejm.org/doi/full/10....

Et voilà ! On le dit depuis le début… et c’est la même chose pour les spécialistes Êtes-vous vraiment surpris que le ministère aurait pu se tromper dans ses calculs ? Non ! www.lapresse.ca/affaires/chr...

𝗕𝗮𝗰𝘁𝗲𝗰 𝗙𝗫 @ 𝗦𝘁-𝗝𝗲𝗿𝗼𝗺𝗲 New device for BC next monday! Main changes :  1. New bottles w/ thin cap 2. Finally enough space for 4 bottles/pt! Bacteremia detection ability expected to go up by ~ 5% 3. We’ll start to use diversion to reduce contamination rates by an expected 60% #IDSky #MicroSky

On World AIDS Day, remember that HIV risk often changes over time & that our prevention tools keep expanding. PrEP, PEP & PEP-in-Pocket ("PIP") offer strong, flexible protection. A "buffet" approach lets people choose what best fits their lives. tinyurl.com/2zkf3hak

Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice 🔗 https://bit.ly/4pmCEDJ

Can we really be grateful for anything in the ID world in 2025? Sure -- plenty of great advances! Here are a half-dozen to celebrate (and be grateful for) in 2025, believe it or not. #idsky blogs.jwatch.org/hiv-id-obser...

Inspired by this rage-inducing ad, I offer 3 big misses on antibiotics that need to die. paulsaxmd.substack.com/p/three-myth...

Fascinating CID Brief Report ➡️Safe implementation of novel HBV-inactive cART for people living with HIV and prior HBV exposure is of paramount importance and better clinical trial and real-world data is essential to inform best practice

Fascinating CID Brief Report #HIVsky #IDsky « Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice» (Thank you @josephmarcusid.medsky.social for flagging it) academic.oup.com/cid/article/...

A great @cidjournal.bsky.social case series that led to lots of discussion with the fellows today- 4 🇬🇧 pts with HBV reactivation after change off of a TAF-based HIV regimen Pt1/4: +HBcAB, -HBVsAg, -HBVsAB Pt2/3: +HBcAB, -HBVsAg,+HBVsAB #IDSky academic.oup.com/cid/advance-...

🆕🔥🦴 Our 2025 Update to @wiki-guidelines.bsky.social for the Management of Pyogenic Osteomyelitis in Adults 🌟 @bradspellberg.bsky.social 🔗 [link] #idsky www.amjmed.com/article/S000...

Le président du CMDP, Michel L’Allier;« On travaille beaucoup avec des cancers, et nous, qu’est-ce qu’on fait quand il y a un cancer ? On l’enlève. Quand une loi n’est pas bonne et que c’est un cancer pour le système de santé, on l’enlève » #Loi2 = ⚠️ et 💩 www.lapresse.ca/actualites/s...

Je suis un médecin. Je ne quitterai pas le Québec. Je serai « ailleurs » dans ma tête. Tout simplement. Strict minimum. Zéro motivation. #JeMeSouviens #Loi2

Anal cancer screening: a balanced approach is necessary ✅ Just Accepted #IDTwitter 🔗 https://bit.ly/4oK9kra

❤️ @wrexhamafc.co.uk Back-to-Back-to-Back Racecourse ground #history

That’s a wrap ! Back home after my first « on site » @aasldnews.bsky.social Liver Meeting @ Washington DC It was my first non-HIV meeting (outside 🇨🇦) in ~ 10 years. Way overdue 👍 #TLM2025 p.s. The snow was waiting for me…

Tobevibart plus elebsiran and tobevibart alone both lowered HDV RNA and ALT levels. The combination resulted in a high incidence of undetectable HDV RNA and an HBsAg level below 10 IU/ml at week 48. Full SOLSTICE phase 2 trial results: nej.md/4qIXpuM @aasldnews.bsky.social | #TLM25

My eyes were bleeding 🩸 (🇮🇳 RCT, HCV, SOF/VEL 8w vs 12w)

Chess and pickelball #TLM2025 😅

« This is the water that I swim in » Powerful talk by Wendy Lo #TLM2025 #HBV @aasldnews.bsky.social

Selfie with @suwang88.bsky.social ✅ #HBV #TLM25 @aasldnews.bsky.social

Should I Worry About the Pasta? The ID Doctor as News Translator (Hello #IDSky and #Medsky! Trying out some different venues for writing, so hoping you'll subscribe -- it's free!) open.substack.com/pub/paulsaxm...