That’s a wrap ! Back home after my first « on site » @aasldnews.bsky.social Liver Meeting @ Washington DC It was my first non-HIV meeting (outside 🇨🇦) in ~ 10 years. Way overdue 👍 #TLM2025 p.s. The snow was waiting for me…

Tobevibart plus elebsiran and tobevibart alone both lowered HDV RNA and ALT levels. The combination resulted in a high incidence of undetectable HDV RNA and an HBsAg level below 10 IU/ml at week 48. Full SOLSTICE phase 2 trial results: nej.md/4qIXpuM @aasldnews.bsky.social | #TLM25

My eyes were bleeding 🩸 (🇮🇳 RCT, HCV, SOF/VEL 8w vs 12w)

Chess and pickelball #TLM2025 😅

« This is the water that I swim in » Powerful talk by Wendy Lo #TLM2025 #HBV @aasldnews.bsky.social

Selfie with @suwang88.bsky.social ✅ #HBV #TLM25 @aasldnews.bsky.social

Should I Worry About the Pasta? The ID Doctor as News Translator (Hello #IDSky and #Medsky! Trying out some different venues for writing, so hoping you'll subscribe -- it's free!) open.substack.com/pub/paulsaxm...

HBV siRNA vs ASO : in a nutshell #TLM2025 @aasldnews.bsky.social

HBV HCC screening @aasldnews.bsky.social 2025 guidelines #TLM2025

Washington DC @ #TLM2025 @aasldnews.bsky.social 🔥Hot Topics in Hepatitis B : New Clinical Tools for Hepatitis B Management (after my 10 km)

🆕🔥State-of-the-Art Review with 🌟s @trubianojason.bsky.social : Antibiotic Allergy—A Multidisciplinary Approach to Delabeling #idsky url: academic.oup.com/cid/article/...

@glaucomflecken.bsky.social hitting close to home with this ID doc at the soccer game.... Reflexively, I couldn't help screaming in my head...don't put DEET on the net, only use permethrin on clothing!! #IDSky www.youtube.com/shorts/Q8UGF...

🆕 AASLD/IDSA Practice Guideline on treatment of chronic Hepatitis B @aasldnews.bsky.social @idsainfo.bsky.social journals.lww.com/hep/abstract...

Loi 2 : CAQ(A)strophe 💩

Système de santé québécois « in a nutshell »

#Loi2 Legault persiste et signe ce PM en conférence de presse; «  Mais, il faut à un moment donné laisser la poussière retomber. » Ce nest pas de la poussière. C’est un tas de roches 🪨

#Loi2 💯 👇 www.lapresse.ca/actualites/c...

Loi 2 « Elle-même médecin, la fille de Lionel Carmant pourrait quitter le Québec » Et voilà! Quand même ton PÈRE ministre n’est pas capable d’expliquer les bienfaits de la Loi 2 et/ou de te convaincre.

De quoi parle les médecins spécialistes aujourd’hui ? - de la Loi 2 de 💩 - du DSQ de 💩 qui est toujours en panne et nous empêche de TRAVAILLER Votre réseau est brisé

Carrés Bleus #Loi2

RASSEMBLEMENT CITOYEN Samedi 1er novembre 2025 – 10h -Devant l’Assemblée nationale du Québec -Pour défendre notre santé, notre démocratie, notre avenir

Ladies and gentlemen, mesdames et messieurs; Loi 2 (Law 2) @ Québec, 🇨🇦

Mic Drop

Ministre @cdubesante.bsky.social ; beau mensonge sur la réduction $ de nos actes à TLMEP Allez relire votre loi.

#Loi106 💩 Lecture obligatoire

Quelle triste journée pour les soins de santé au Québec #Loi106

Vous pouvez bien rire comme vous voulez chers gens qui méprisent les médecins parce qu'ils font un maudit bon salaire. Cette Loi 106 va détruire nos soins. Pas l'améliorer. Mark my words. Bonne chance à tous 🤦‍♂️

Message de ma femme médecin spécialiste qui n’a JAMAIS manqué une journée de travail de sa vie malgré tout ça (incluant le jour de sa fausse couche… je m’en souviens comme si c’était hier 💔) Et je viens de démissionner de; -recherche clinique -médecin conseil santé publique Priorité loi 106 …. 🤮🤷‍♂️

🆕🔥🔥CloCeBa RCT Cloxacillin versus cefazolin for MSSA Bacteraemia Cefazolin has a non-inferior efficacy regarding mortality, microbiological or clinical endpoints and was associated with a lower rate of serious adverse events #IDSky www.thelancet.com/journals/lan...

What the DOTS trial of Staph bacteremia tells us: • Dalbavancin d1 and d8 vs daily IVs for WEEKS • No left-sided IE/CNS/prosthetics • Dalba not superior by DOOR endpoint, but similar clinical outcomes. Big implications for inpt care. More here! #IDSky tinyurl.com/3hjzkt96

Everything is a zoonosis!drawing/listing challenge #18- Deer This got me thinking *what* is a zoonosis? Per WHO they r ifx “naturally transmissible from vertebrate animals to humans” I’ve seen Lyme referred to as “vector-borne zoonotic disease” And what is a reservoir? Thoughts #IDSky #VetSky?

Not too bad for my first half marathon (and after a stress fracture in April)

How much evidence is needed to revise established clinical practices? and, can data alone truly catalyze such shifts? Our 🆕🔥 Article at @cidjournal.bsky.social with 🌟s @bradspellberg.bsky.social Practicing With Intent: How to Teach an Old Dogma New Tricks #IDSky academic.oup.com/cid/article/...

What a strange and unusual week 🏥 (for me…) - asked for BPaL TB treatment - saw a case of probable Leprosy (high suspicion, to be continued) We have the best medial specialty 🤷‍♂️ #IDsky

The latest in the controversy between 3 vs 2 drugs for HIV treatment -- now in advanced HIV disease, with the DOLCE study. @drlaurajwaters.bsky.social #IDSky #HIVsky blogs.jwatch.org/hiv-id-obser...

Today, a dermatologist called me and asked 6 weeks of Ertapenem OPAT for a case of « severe suppurative hidradenitis » I said no. That’s it. That’s the post. #IDsky

2025 US Public Health Service Guidelines for the Management of Occupational Exposures to HIV and Recommendations for PEP in Healthcare Settings 🤯lots of NAT, no ?

🤯Montreal 🚴

Bookmark option now available #BlueSky #IDsky

Long-acting cabotegravir/rilpivirine in viraemic people with HIV: bumpy raod to perfection ✅ Just Accepted #IDSky

Hepatitis B transmission, dalbavancin for staph bacteremia, alpha-gal allergy, vaccine policy shifts, too much screening in pt care ... Some end-of-summer ID musings, with scattered other thoughts silly and not ID-related at all. And tennis, of course! #IDSky blogs.jwatch.org/hiv-id-obser...

For us ID doctors, the CDC has been a rock. Data, guidelines, surveillance, travel advice -- all there, vetted by experts, referenced, reliable. Perfect? No. But watching its dismantling now breaks my heart. Some thoughts: blogs.jwatch.org/hiv-id-obser...

Some great comments -- both pro and con -- have come in response to this post about screening for anal cancer in PWH. Would welcome further opinion, especially from clinicians seeing patients regularly and/or experts in cancer screening. blogs.jwatch.org/hiv-id-obser...

Amazing case below #IDsky 🤯 ICU for presumed septic shock, purpura fulminans, DIC. Blood cultures (-) and no focus of infection. Blood smear flagged for «unsual» structures inside WBCs (see photo) ➡️ Can you guess the Dx ? (we did 😉, now confirmed by 16S rRNA of initial blood culture)

Rocky Mountain Spotted Fever (RMSF) in Quebec, 🇨🇦 from Dr Alex Carignan

The anal cancer screening guidelines for PWH recommend testing every 1-2 yrs. But the evidence base is thin, the tests are imperfect, and resources are limited. Here's why guidelines may be racing ahead of the data (and certainly the resources). #IDSky #HIVSky blogs.jwatch.org/hiv-id-obser...

Calling all HIV/ID providers: How many are able to do this screening for anal cancer according to IANS? Including the HRA and repeat screening every 1-2 years (!!) for normal results? Wow, that's a lot of screening tests in a lot of people! #IDSky #HIVsky onlinelibrary.wiley.com/doi/10.1002/...

Mind 🤯 HBV case ⬇️ #IDsky 🇨🇳 pegIFN Tx >15y ago, then TDF Under my care x 2021, TDF continued; F0-F1, HBV DNA undetectable HBsAg(+) ➡️ (-) (qHBsAg <10) antiHBsAg(-) ➡️ antiHBsAg(+) >10 HBeAg (+), anti-HBeAg (-) ⚠️TDF d/c x December 2024 (1/2)

First case of 🇺🇸 VRSA since 2015: 🧫 DFI wound culture at site of previously treated MRSA + E. faecalis 🧫 New co-infection VRSA + VRE 🧫 Mechanism: harboring VanA gene ✅ Successfully treated with Dapto 🧫 No contacts with VRSA colonization #IDSky