My alma mater is hiring a microbiologist! Assistant/Associate Prof. 👇👇

Congratulations to Kathryn Rahlwes and the rest of the team on the new preprint from our group. We identify USP15, a deubiquitinase, as a key brake on macrophage immunity to Mycobacterium tuberculosis (Mtb). Remove it, and macrophages control Mtb far more effectively. www.biorxiv.org/content/10.1...

Congrats @samuelalvarez.bsky.social and the entire team on this work characterizing established (i.e. M cells) and new cells in the mucosal immune system! The new cells we named WISP cells as they are found in both adenoid and tonsils. Read the paper to find out so much more!

Quantifying Dissemination of Antibiotic Resistance Genes in Air from a Dairy Farm and Swine Farm, led by PhD student David Kormos, now published! We found ARGs in a range of particle sizes, indicating potential for inhalation exposure and long-range transport. pubs.acs.org/doi/10.1021/...

Congrats to Dhananjay Naik from @tedpricethepainguy.bsky.social's lab at UT Dallas on their new preprint deeply characterizing the nociceptive activity of SL-1 on mouse & human neurons. www.biorxiv.org/content/10.1...

Enjoyed celebrating John Neff’s PhD graduation ceremony yesterday.

🦠💨 Why do some TB strains make you cough more? Cough isn’t just an annoying sign and symptom of active tuberculosis - it’s one way that Mycobacterium tuberculosis spreads from person to person. 1/14 #Tuberculosis #CoughScience #Aerobiology #Neuroimmunology #Microbiology youtu.be/9qqHOKUXY5U?...

Celebrating the next PhD to leave the lab. Congratulations Dr. Neff. As per Shiloh lab tradition, John’s graduation cake represents Activity Based Proteomic Profiling with rock candy “proteins”.

Michael Oliver needs to be investigated for corruption. This is not a joke.

Scientists and Physicians I’m being serious here —at this precarious juncture, along with all other defensive and support strategies, it is important to seize the public narrative—high level investment and leadership in medical discovery and innovation is unabashedly patriotic! USA! USA! USA!

First ever “Great Shiloh Lab Bake Off” was a big success. Loaf cake/bread was the assignment. Congrats to all 6 bakers and thanks to the 3 judges. Bakes were judged anonymously and comments were kind but fair.

Lab Secret Santa today was a big hit. Really enjoyed my gifts!

And just like that, Ms. Monard leveled up to Dr. Monard! 🥳🎓 Proof that caffeine, stubbornness, and 0.05 p-values can work wonders. Congratulations, ⁦‬Sarah! 🚀🔬 #PhDone

Sarah wrote an incredible thesis manuscript and presented a masterful defense. Kudos!

Believe it or not, GRC has told me we need more registered applicants or this meeting might not survive! Please don't let that happen if you can afford to attend 🙏

It was a wonderful thesis defense and I'm glad I was able to participate! Congrats to Sarah and her mentorship team!

Congratulations to Samuel Alvarez-Arguedas, our bioinformatics collaborators in Ted Price's lab and our clinical collaborators UTSW Medical Center on Sam's preprint describing the in depth transcriptional profiling of human adenoid cells. www.biorxiv.org/content/10.1...

Congratulations to Vickie Ektnitphong on submission of her paper, with help from Beatriz Dias & Priscila Campos. We describe application of an "alveolus-on-a-chip" device for the study of alveolar infection by a model non-tuberculous mycobacteria, M. fortuitum. www.biorxiv.org/content/10.1...

A short read on post-infectious cough.

Addgene will no longer be using X, formerly Twitter. Instead, we'll be posting our 'microblogging' content here on Bluesky. blog.addgene.org/addgene-is-s...

Watching Arsenal play these days is about as painful and frustrating as watching the Eagles. Sigh.

I’m sure this will be a fantastic meeting.

The final version of Josephine's paper is now online at Journal of Clinical Investigation. Congrats again to all the authors. www.jci.org/articles/vie...

New collaborative paper with Michaela Kress lab in Austria just published in iScience: www.cell.com/iscience/ful... If you are interested non-coding RNAs in human DRG neurons, this is the paper for you! Led by Max Zeidler in Michaela's lab and Diana Tavares-Ferreira in my lab + Jackson Brougher

Check out this preprint by Lindsay Guzman in Carolyn Bertozzi’s lab on bioorthogonal labeling of Mtb phenolic glycolipid.

Due to the ongoing situation in Israel, we have decided to postpone the ISM2024 meeting. We will announce the new dates once they are available. I hope that by then, all the hostages (babies, children, women and men) held by the vile terror organization Hamas will be released.

Our paper on the role of CDKL5 in selective autophagy of viruses if now online. Congrats to all the authors. www.jci.org/articles/vie...

Celebrating the formal acceptance of Josephine’s paper in Journal of Clinical Investigation! In press proof to be released in two days!

Had a great time visiting Cornell University in Ithaca last Friday on a gorgeous and warm fall day. Thank you to Brian VanderVen for hosting my visit and for the campus tour.

Fantastic Levine Prize lecture yesterday by Noburo Mizushima from the University of Tokyo. He not only eulogized Dr. Beth Levine in the most elegant way possible, but also provided a great history of autophagy research & amazing cutting-edge & unpublished science.

Introduce yourself with some jobs you've done apart from what you do now: - Paperboy - Supermarket bagger - Circuit board assembler - Busboy/ice cream and waffle maker - Dish/pot washer - Lab technician - Medical moonlighter