An efficient and mild dibromination of aromatics using Fe(NO₃)₃·9H₂O/FeBr₃ at room temperature. This protocol delivers good to excellent yields, avoids hazardous Br₂, and is scalable to gram scale. 🧪 🔗 Read here: bit.ly/4riD0gk #ChemSky #OrganicSynthesis #Halogenation #GreenChemistry

🌱 Polar organometallic reagents can thrive in #sustainable solvents! This graphical review highlights how organolithium, #Grignard, and related #reagents operate in water and deep eutectic solvents, redefining classical reactivity through #GreenChemistry. 🔗 Read now: bit.ly/4qVloXj #ChemSky

🧩 Sterically controlled, template-assisted macrocyclization enables hemisquaraine #rotaxanes with enhanced #fluorescence and stability. By combining #SupramolecularChemistry, photophysics, and DFT, this study reveals how steric effects control rotaxane formation. 🔗 Read here: bit.ly/3ZE8UaF

Asymmetric synthesis of 2-arylethylamines, key motifs in bioactive compounds and #MedicinalChemistry. This graphical review highlights 2025 advances in metal-free and metal-catalyzed methods, including #Organocatalysis, #Photocatalysis and #Biocatalysis. 🧪 🔗 Read here: bit.ly/3LORTHq #ChemSky

⚡ Turning alcohols into aldehydes with electricity. New open-access graphical review on electrochemical oxidations in @synopenjournal.bsky.social by @Conchem.bsky.social because chemists love schemes more than words 🤣 www.thieme-connect.com/products/ejo... #Electrosynthesis #Aldehydes #ChemSky

Discover how [2.2]paracyclophanes (PCPs) are functionalized using transition #metals and applied as planar #chiral ligands and catalysts. This graphical review offers a overview of C–H activation strategies and their impact on #stereoselective synthesis. 🔬📘 🔗 Read here: bit.ly/4qwWRb7 #ChemSky

An iodine-doped TiO₂ #photocatalyst shows efficient degradation of toxic dyes under UV and visible light, with enhanced activity and good reusability. A promising approach for sustainable #WaterTreatment. 🌱💧 🔗 Read the full article: bit.ly/4r2zgit #OpenAccess #ChemSky #SustainableChemistry

We’re live! Introducing Therapeutics NOW – Thieme’s new Gold Open Access journal driving breakthroughs in translational therapeutic research. ✅ Interdisciplinary by design ✅ Broad scope & impactful article formats ✅ Ultra-fast peer review via Select Crowd Review 🔗 www.thieme.com/en-us/thieme...

⚡🔬 Can #ElectricFields direct #ChemicalReactivity? This graphical review by Prof. Thomas Wirth & team (🇬🇧) shows how oriented external electric fields can control reaction pathways, enhance selectivity, and reduce energy input in #OrganicSynthesis. A must-read! 🔗 bit.ly/453gvCT #ChemSky #OpenAccess

✨ 2025 highlights ✨ 🥇 #1 Most Downloaded Paper of 2025 “Sodium Nitrite (NaNO₂): An Impressive and Efficient Nitrating/Nitrosating #Reagent in #OrganicSynthesis” Graphical review by Lamark, Barbosa & Jordão 🔗 Read now: bit.ly/4b9Di3x #ChemSky #Chemistry #OpenAccess

✨ 2025 highlights ✨ 📊 Top 5 most downloaded papers of 2025 ✅ #2 A convenient #synthesis of CHF₂O-containing #pyrrolidines and related compounds — Perspective building blocks for #DrugDiscovery by K. Levchenko et al. 🔗 Read here: bit.ly/498FiGQ #ChemSky #OrganicChemistry

✨ 2025 highlights ✨ 📊 Top 5 most downloaded papers of 2025 ✅ #3 “Synthesis, In Vitro and In Silico Molecular #Docking Studies of Novel Phthalimide–Pyrimidine Hybrid Analogues to #Thalidomide as Potent #Antitubercular Agents” by S. Youssif & team 🔗 Read now: bit.ly/49cOqKG #ChemSky

✨ 2025 highlights ✨ 📊 We’re closing the year with the Top 5 most downloaded papers of 2025. ✅ #4 “Recent #Catalytic Applications of #Porphyrin and Phthalocyanine-Based Nanocomposites in #Organic Transformations” by P. Kumari & co-workers 🔗 Read now: bit.ly/48URmwu #ChemSky

✨️ 2025 highlights ✨️ 📊 Our final posts of the year highlight the Top 5 most downloaded papers of 2025. ✅ #5 “Development of a Novel Horner–Wadsworth–Emmons Reagent for the Facile Preparation of Mixed Phosphonoacetates" by Shigeki Sano & team. 🔗 Read it here: bit.ly/3YcSdT2 #ChemSky #Chemistry

✨ 2025 highlights ✨ A year of global connections and great #science for the Syn journals community: 10 events across 8 countries! 🇨🇭 🇰🇷 🇪🇸 🇬🇧 🇨🇳 🇯🇵 🇵🇹 🇮🇹 Thank you to everyone who made these meetings unforgettable! Special thanks to @rohitbhatia10.bsky.social 🇮🇳 for representing us at so many conferences!

🎄 2025 highlights! 🎄 The SynOpen Best Paper Award 2024 to Ben Stokes & co-workers (Santa Clara University, 🇺🇸) for their publication "Pd-Catalyzed Transfer Hydrogenation of Alkenes Using Tetrahydroxydiboron as the Sole Hydrogen Donor" 👀 Revisit the paper: bit.ly/3MSJsuR #Throwback #ChemSky

🎄 As 2025 comes to a close, we at @thieme-gruppe.bsky.social look back at our #Cheminar series! From Chemical Synthesis & #Catalysts to Medicinal #Chemistry, plus special sessions and Best Paper Awardees. Thanks to all chairs, speakers, and attendees. 👀 More Cheminars in 2026. Stay tuned!

📢 Last call for our Thieme #Cheminar! Dive into the world of Small #Molecules in Medicinal Chemistry. Session with Profs. Arlene G. Corrêa (🇧🇷) & Kelvin Billingsley (🇺🇸), chaired by Debabrata Maiti (🇮🇳). 📅 Dec 10, 2025 ⏰ 5 PM (CET) 🔗 Register now: bit.ly/4aDJWie #ChemSky

📢 Cheminar Alert! Our next Thieme #Cheminar is coming up: “Small Molecules in #MedicinalChemistry” 📅 Dec 10, 5:00 PM (CET) Featuring Prof. Arlene Corrêa and Prof. Kelvin Billingsley, with Prof. Debabrata Maiti (EiC of @synlettjournal.bsky.social) chairing. 🔗 Register now: bit.ly/4aDJWie #ChemSky

🧬 New #anticancer candidates from functionalized oxazoles! M. V. Kachaeva & team report 5-S-substituted 1,3-oxazolylphosphonates and 1,3-oxazole-4-carbonitriles, with several compounds showing high potency against multiple #cancer cell lines! 📄 Read here: bit.ly/4pmeAl4 #ChemSky #MedChem #Synthesis

🔬 Prof. Ying Xia and colleagues highlight recent advances in the #synthesis of axially #chiral cycloalkanes, covering key strategies such as asymmetric allylic substitution, #alkene insertion, #carbene cross-coupling, [2+2] #cycloadditions, and #deracemization. 🔗 Read now: bit.ly/4pCRhTy #ChemSky

Potential new type of #herbicides! 🌱 In this paper, J. Frackenpohl & team report the design, #synthesis, and #biological evaluation of substituted azetidinyl carboxamides, developed through scaffold hopping and #bioisosteric strategies. 🔗 Read the full article: bit.ly/4iplJyn #ChemSky #SAR

Prof. Michael P. Doyle & L. De Angelis (UTSA) highlight how 1,2,3-triazine 1-oxides provide a powerful platform for constructing diverse #heterocycles. From nucleophilic substitution & #deoxygenation to Diels–Alder #reactions and more! 🔗 Read the graphical review: bit.ly/48qm7Jg #ChemSky #Synthesis

✨ New Graphical Review! A. V. Dobrydnev presents overview of synthetic strategies for building endocyclic sulfoximines. They possess unique #physicochemical and structural features, including #chirality and thermal stability. 🔗 Read more: bit.ly/482WRr7 #ChemSky #OrganicChemistry #Heterocycles

⚡ In this review, J. Yang & team highlight recent advances in metal-enabled #electrophotocatalysis, integrating photo-, electro-, and metal-catalyzed processes to develop #sustainable routes for C–H activation, #decarboxylation, and cross-coupling under mild conditions. 🔗 Read now: bit.ly/43vqgZH

M. V. Kachaeva & team designed and synthesized novel oxazolo[4,5-d]pyrimidine derivatives showing strong activity against glioblastoma and lung #cancer cell lines. 🔍 #MachineLearning, #QSAR modeling, and #docking revealed carbonic anhydrase XII as a potential target. 👉 Read more: bit.ly/47NQt75

🚀 Countdown to SCNOW Virtual Summit, 6–7 Nov! 🌱♻️ Join top experts in sustainable & circular chemistry from #academia, #industry & #policy. Connect, exchange ideas & drive impact. 💻 Register NOW: cassyni.com/s/scnow-virt... #SCNOWVirtualSummit #SCNOWPosterSession #Sustainability

⚗️ A mild and #metal-free route to 2-hydroxy diarylureas! This PIFA-mediated ring-opening/coupling of benzoxazoles gives valuable #urea scaffolds with high yields and broad substrate scope. 🔗 Read the full article by M. Yang & team: bit.ly/47rBv81 #ChemSky #OrganicChemistry

🌱 From the Virtual Collection: #ClickChemistry and #DrugDiscovery A simple, metal-free, and eco-friendly approach using chitosan·HCl enables rapid hydrazone #synthesis under mild conditions, delivering high yields and promising #antimycobacterial activity. 🔗 Read here: bit.ly/3WZ09Xl #ChemSky

🧩 From the Virtual Collection: #ClickChemistry and #DrugDiscovery An efficient click-type formal [2+2] cycloaddition enables the formation of complex #chromophores with remarkable nonlinear optical (NLO) properties. 🔗 Read the full paper: bit.ly/4qpq87O #ChemSky #OrganicChemistry #OpenAccess

⚗️ From Virtual Collection: #ClickChemistry and #DrugDiscovery N. Jahan & I. Ansary present a review on the synthesis of bioactive macrocycles using ring-closing metathesis, a powerful strategy enabling access to structures with promising #biological activities. 👉 Read here: bit.ly/4hjC3jv #ChemSky

​🚨 LAST CALL! The Thieme #Cheminar starts TODAY. ​Join the session, chaired by our EiC, Prof. Thierry Ollevier. ​Plus: Hear from the SynOpen Most Innovative Paper Award 2024 Winner, Prof. Benjamin Stokes! ⏰️ Starts 3:00 PM (CET). 🔗 Register now: bit.ly/48sqMLq #ChemSky #Chemistry #Boron

Join the next Thieme #Cheminar focusing on the role of boron in #OrganicSynthesis! ​Chaired by our SynOpen Editor-in-Chief, Prof. Thierry Ollevier. ​📅 Oct 16, 3 pm (CEST) ​Don't miss the opportunity to connect with leaders in the field! ​🔗 Secure your spot: bit.ly/48sqMLq #ChemSky #Chemistry

The Nobel Prize in Chemistry 2025 was awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi "for the development of metal-organic frameworks." Congratulations! 🎉 ​Full details: www.nobelprize.org/prizes/chemi... #ChemNobel #ChemSky #Nobel #Science

🧩 From the Virtual Collection: #ClickChemistry and #DrugDiscovery Vinod K. Tiwari & team report a modular and efficient click approach for the synthesis of calix[4]arene-based glycodendrimers bearing lactose (G1) and galactose (G2) units. 👉 Read now: bit.ly/46Vjb5I #ChemSky

✨ From Graphical Reviews Virtual Collection Liu & Szostak highlight breakthroughs in #amide N–C bond #activation, covering: ⚡ Acyl & decarbonylative coupling ⚡ Nucleophilic acyl addition ⚡ Key mechanistic insights Read here: www.thieme-connect.com/products/ejo... #ChemSky #Catalysis #Chemistry

🏆 Big news from SynOpen! The Most Innovative Paper #Award 2024 goes to Benjamin Stokes & team (Santa Clara University, USA) for their breakthrough in Pd-catalyzed transfer #hydrogenation. Congratulations! 🎉 👏 👉 Read more in the full press release + article: www.thieme.de/en/thieme-ch...

⚡ From Graphical Reviews Virtual Collection #Electrochemistry offers sustainable C–Se bond formation! Explore selenylation, difunctionalization, #cyclization & cross-coupling in this graphical review by Hasimujiang & Ruan. 🔍 Read now: www.thieme-connect.com/products/ejo... #ChemSky

✨ #PeerReviewWeek2025 highlights the future of peer review in the AI era. At SynOpen Journal, we recognize the potential of AI to assist reviewers and strengthen integrity, but also the need for transparency, safeguards, and a continued focus on human expertise. #AI #PeerReview #OpenAccess #Thieme

✨ From Graphical Reviews Collection #Chemical transformations of indole #alkaloids provide rapid access to novel scaffolds for #DrugDiscovery. Ring distortion strategies re-engineer natural products into diverse bioactive compounds. 🔍 Read now: www.thieme-connect.com/products/ejo... #ChemSky

✨ From Graphical Reviews Virtual Collection Frustrated Lewis Pairs (FLPs) go beyond H₂ #activation, enabling hydroaminations, #oxidations, cycloisomerizations, and C–C/C–N bond formations. 🔍 Read the graphical #review by Zhou, Tavandashti & Paradies: www.thieme-connect.com/products/ejo... #ChemSky

🔬 Donor–acceptor azulenes with absorption in the 380–600 nm range & intense blue photoluminescence open new paths for functional materials in organic optoelectronics. 📖 Explore the article by Merkhatuly et al.: www.thieme-connect.com/products/ejo... #ChemSky #Science

⚗️ Vicarious Nucleophilic Substitution (VNS) opens new doors in porphyrin #chemistry! VNS reaction enables the synthesis of functionalized #porphyrin derivatives with wide synthetic potential. 📖 Explore the graphical review by Ostrowski & Mikus: www.thieme-connect.com/products/ejo...

@lcsolab.bsky.social delegation at #ISySyCat2025 www.linkedin.com/feed/update/... Congrats Adriana for the SynOpen Poster Prize!

🧪 Explore the latest in #chlorination #science with the graphical review by Vogel, Pinto & Candeias. From green methods to novel reagents, discover sustainable strategies shaping #OrganicSynthesis! 🔗 Read here: www.thieme-connect.com/products/ejo... #OpenAccess #Chemistry

🔬 Explore the synthetic versatility of Woollins’ Reagent (W.R.)! From heterocycle formation to selenoic acid #synthesis, discover its wide-ranging applications! Check out the graphical review by da Silva, Chipoline & Ferreira for more. 🔗 Read here: www.thieme-connect.com/products/ejo...

🚀 Big news from SynOpen! We’ve reached an Impact Factor of 2.1 in the 2024 JCR, placing us in Q3 of ESCI! 🌟 💙 Thanks to our authors, reviewers, board & readers. Submit your manuscript and join our growing community in #ChemicalSynthesis. Let’s advance #science together—fast, fair & open!

✨Our August Thieme #Cheminar dedicated to prof. Carreira was a big success with 406 attendees at peak!✨ Thanks to everyone who joined the discussions, our speakers for the excellent presentations👏, and our EiC @marklautens.bsky.social for chairing the session! Watch later👉 buff.ly/K2XxagR

📢 Happening Today! Last chance to register for the #ThiemeCheminar honoring Prof. Erick Carreira. Don’t miss outstanding talks from our fantastic speakers! ⏰ Today, August 14 – 3 PM (CET) 👉 Register here: cassyni.com/events/YCqA8...

Explore the world of #Deuteration! 🧪🔬 This graphical review dives into transition-metal-catalyzed H/D exchange, unraveling #mechanisms, diverse #catalysts, and applications in precise deuterium labeling. Don't miss it! 🔗 Read now: www.thieme-connect.com/products/ejo... #Chemistry #OpenAccess