Álvaro Acosta Serrano
@aacostaserrano.bsky.social
📤 207
📥 293
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Professor of Vector Biology and Parasitology at the University of Notre Dame, USA
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Álvaro Acosta Serrano
Dr Joanne Power
about 2 months ago
Save the dates!!
@bspparasitology.bsky.social
Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026! Keep an eye on the BSP website for registration and abstract submission! Logo by
@shannaraeilean.bsky.social
! 🦟
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Zachary Stavrou - Dowd
3 months ago
Marvel hasn’t called yet, but “Mosquito Slayer: Origin” has a nice ring to it..... Thank you for covering our work
@aacostaserrano.bsky.social
@lstmnews.bsky.social
@notredame.bsky.social
doi.org/10.1186/s130...
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Ana Flores-Mireles
3 months ago
Check out this awesome study from our Notre Dame colleagues,
@aacostaserrano.bsky.social
and Lee Haines!! Nitisinone kills insecticide-resistant mosquitoes through cuticular uptake
parasitesandvectors.biomedcentral.com/articles/10....
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The β-triketone, nitisinone, kills insecticide-resistant mosquitoes through cuticular uptake - Parasites & Vectors
Background Insecticide resistance in disease-transmitting arthropods of agricultural, veterinary, and public health significance poses a significant threat to vector control programs worldwide. Previo...
https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-025-06939-0
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Zachary Stavrou - Dowd
3 months ago
Just out: LSTM’s blog post on our latest paper exploring how nitisinone kills malaria mosquitoes, even the resistant ones, through tarsal contact. From rare disease drug to vector control tool.
@aacostaserrano.bsky.social
📄 Paper:
doi.org/10.1186/s130...
#malaria
#vectorcontrol
#entomology
#HPPD
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Here we show that
#nitisinone
kills insecticide-resistant mosquitoes via cuticular uptake. Great work Zach Stavrou-Dowd, Lee Haines, & LITE. Thanks
@gatesfoundation.bsky.social
& @RoseTrees Trust
@notredame.bsky.social
@lstmnews.bsky.social
parasitesandvectors.biomedcentral.com/articles/10....
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The β-triketone, nitisinone, kills insecticide-resistant mosquitoes through cuticular uptake - Parasites & Vectors
Background Insecticide resistance in disease-transmitting arthropods of agricultural, veterinary, and public health significance poses a significant threat to vector control programs worldwide. Previo...
https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-025-06939-0
3 months ago
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Kristin Michel
6 months ago
New paper from the lab: Bianca Morejon defines the regulatory protease network that governs
#mosquito
#immunity
www.pnas.org/doi/10.1073/...
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The expanded immunoregulatory protease network in mosquitoes is governed by gene coexpression | PNAS
Serine protease cascades regulate key innate immune responses. Their activation cleaves a series of inactive protease zymogens, which then activate...
https://www.pnas.org/doi/10.1073/pnas.2425863122
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theconversation.com/ivermectina-...
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Ivermectina y nitisinona: las dos últimas armas antimosquitos para luchar contra la malaria
La creciente resistencia de los plasmodios y de sus mosquitos vectores frente a fármacos e insecticidas está incentivando la elaboración de nuevas herramientas terapéuticas contra la malaria.
https://theconversation.com/ivermectina-y-nitisinona-las-dos-ultimas-armas-antimosquitos-para-luchar-contra-la-malaria-254081
7 months ago
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www.thenakedscientists.com/articles/int...
Many thanks to Chris Smith and the @NakeScientists for the short podcast about our recent publication on
#Nitisinone
&
#Anopheles
#mosquitoes
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Safe human drug can poison mosquitoes
Another potential mitigation for malaria...
https://www.thenakedscientists.com/articles/interviews/safe-human-drug-can-poison-mosquitoes
7 months ago
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Heather Ferguson
7 months ago
Good news - after 76 yrs with no new drug for rhodiensese Human African Trypanosomiasis,
@who.int
has faciliated research, development & now delivery ofmore effective fexinidazole to replace suramin & melarsoprol. Huge benefit given harsh side effects of the latter.
www.who.int/news/item/07...
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WHO delivers fexinidazole to Malawi and Zimbabwe – a long-awaited safer treatment for rhodesiense human African trypanosomiasis
In a major breakthrough for rhodesiense human African trypanosomiasis (r-HAT) treatment, in August 2024 WHO recommended fexinidazole to replace suramin and melarsoprol as the first-line treatment for ...
https://www.who.int/news/item/07-02-2025-who-delivers-fexinidazole-to-malawi-and-zimbabwe---a-long-awaited-safer-treatment-for-rhodesiense-human-african-trypanosomiasis
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Thanks Jason Bittle & National Geographic
@hgl7.bsky.social
4 the nice piece
www.nationalgeographic.com/science/arti...
about our recent paper on nitisinone & malaria control
www.science.org/doi/10.1126/...
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To fight malaria, scientists want to poison mosquitoes—with human blood
Low doses of a drug already approved for treating rare genetic conditions in humans kills mosquitoes dead. Scientists say it could be a valuable new tool in the fight against disease.
https://www.nationalgeographic.com/science/article/mosquito-human-blood-poison-drug-malaria?loggedin=true&rnd=1743199492046
8 months ago
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Thanks
@freddyfrischknecht.bsky.social
it has been a long road, as usual…
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8 months ago
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Antonio Martínez Ron
8 months ago
Un grupo de investigadores descubre que la nitisinona, que ya se emplea como fármaco contra enfermedades raras, es más eficaz contra los mosquitos que la ivermectina y podría ser una alternativa en la lucha contra la malaria
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Un nuevo compuesto prometedor contra la malaria: convierte tu sangre en veneno para los mosquitos
Un grupo de investigadores descubre que la nitisinona, que ya se emplea como fármaco contra enfermedades raras, es más eficaz contra los mosquitos que la ivermectina y podría ser una alternativa en la...
https://www.eldiario.es/1_b9a656?utm_campaign=botonera-share&utm_medium=social&utm_source=bluesky
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A team effort!
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8 months ago
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Muchas gracias
@elenagomez-diaz.bsky.social
y Carlos!
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8 months ago
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Antonio Martínez Ron
8 months ago
Ya para socios: Un nuevo compuesto prometedor contra la malaria: convierte tu sangre en veneno para los mosquitos
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Un nuevo compuesto prometedor contra la malaria: convierte tu sangre en veneno para los mosquitos
Un grupo de investigadores descubre que la nitisinona, que ya se emplea como fármaco contra enfermedades raras, es más eficaz contra los mosquitos que la ivermectina y podría ser una alternativa en la...
https://www.eldiario.es/1_b9a656?utm_campaign=botonera-share&utm_medium=social&utm_source=bluesky
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Glad this is finally out. Using pharmacokinetic modeling we show that
#nitisinone
, an FDA-approved drug 4
#Tyrosinemia
&
#Alkaptonuria
, kills
#Anopheles
mosquitoes, outperforming
#Ivermectin
. Grateful to all primary author’s & fantastic collaborators!
www.science.org/doi/10.1126/...
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Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone
Nitisinone reduces survival of the malaria-transmitting mosquito Anopheles gambiae by blocking tyrosine catabolism.
https://www.science.org/doi/10.1126/scitranslmed.adr4827
8 months ago
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mara lawniczak
9 months ago
globally, there are ~3500 described mosquito species in the Culicidae family and many of these are important vectors of disease but only a small percentage have genomic resources. we are launching a pilot project to generate high quality reference genomes for 100 important mosquito species [1/3]
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PLOS Biology
9 months ago
PLOS has issued a statement on recent US Executive Orders and scientific integrity. We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry.
plos.io/3D4O8cH
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PLOS statement on recent US Executive Orders and scientific integrity - The Official PLOS Blog
Since its founding over twenty five years ago PLOS has been dedicated to advancing open science, ensuring that knowledge is accessible to…
https://plos.io/3D4O8cH
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Heather Ferguson
9 months ago
'I log on & am bombarded by pictures of things happening outside of Burundi..A non-elected billionaire is answering qs in the Oval Office. He is well-fed & cost of his clothing alone could probably sustain the children in my hospital for a yr. I wonder how we will feed the malnourished babies 2mrw'
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Science Magazine
9 months ago
Breaking news: 22 states are suing to block NIH’s cutting of indirect costs. See our updated story on the Friday night news and its aftermath.
scim.ag/4hTJQ6v
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NIH slashes overhead payments for research, sparking outrage and lawsuit
Move to cut indirect cost rate to 15% could cost universities billions of dollars
https://scim.ag/4hTJQ6v
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Felipe H Santiago-Tirado
9 months ago
Hey
#fungal
people - the applications for this years MOMY course are open! Wonderful course in a wonderful place with wonderful people. Check it out here:
www.mbl.edu/education/ad...
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Ryan Smith
9 months ago
🚨 We are recruiting for two post-doc positions!🚨 1) Development of genetic tools to study mosquito immune cells
isu.wd1.myworkdayjobs.com/IowaStateJob...
2) Role of mosquito immune cells in immune recognition and priming
isu.wd1.myworkdayjobs.com/IowaStateJob...
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Siegel Lab
10 months ago
I’m very much looking forward to attending the symposium and to celebrate the career of Mark Carrington.
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