Anna Cusco
@annacusco.bsky.social
📤 746
📥 791
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Microbiome scientist | Metagenomics | Long-read sequencing Postdoc at Big Data Biology Lab
pinned post!
Finally, the results of my postdoc at the
@bigdatabiology.bsky.social
lab in Shanghai see the light! The work includes my three favorite things research-wise: 🦠 microbiome, 🧬 long-reads, and 🐶 dogs. See our new preprint:
www.biorxiv.org/content/10.1...
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Capturing global pet dog gut microbial diversity and hundreds of near-finished bacterial genomes by using long-read metagenomics in a Shanghai cohort
Pet dogs are considered part of the family, and understanding their gut microbiomes can provide insights into both animal and household health. Most comprehensive studies, however, relied on short-rea...
https://www.biorxiv.org/content/10.1101/2025.09.17.676595v1
4 months ago
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reposted by
Anna Cusco
Svetlana Ugarcina Perovic
3 months ago
New
#MicrobiomeDigest
is OUT
microbiomedigest.com/2025/10/02/o...
• Shanghai dog microbiome /
@annacusco.bsky.social
• microbetag /
@hariszaf.bsky.social
• invitation for the
#MVIF
42 /
@microbiomevif.bsky.social
& more.
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October 3, 2025
See you at the MVIF 42! Human gut microbiomeMicro-scale spatial metagenomics: revealing high-resolution spatial biogeography of gut microbiomes – Carlotta Pietroni – bioRxiv Animal microbiomeCaptur…
https://microbiomedigest.com/2025/10/02/october-3-2025/
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Anna Cusco
If you made it this far, thanks for reading. I hope you enjoyed it. I am currently looking for my next research adventure. If you have insights on the microbiome/microbial genomics job market in Europe (academia & industry), or want to chat about this work, please reach out.
4 months ago
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Anna Cusco
4 months ago
September 2025 updates! A focus on Anna's preprint, but several other updates too, including Faith Adegoke joining us to work on AMR and several other preprints
bigdatabiology.substack.com/p/bdb-lab-se...
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BDB-Lab September 2025 Updates
Dogs and other microbiomes
https://bigdatabiology.substack.com/p/bdb-lab-september-2025-updates
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Finally, the results of my postdoc at the
@bigdatabiology.bsky.social
lab in Shanghai see the light! The work includes my three favorite things research-wise: 🦠 microbiome, 🧬 long-reads, and 🐶 dogs. See our new preprint:
www.biorxiv.org/content/10.1...
loading . . .
Capturing global pet dog gut microbial diversity and hundreds of near-finished bacterial genomes by using long-read metagenomics in a Shanghai cohort
Pet dogs are considered part of the family, and understanding their gut microbiomes can provide insights into both animal and household health. Most comprehensive studies, however, relied on short-rea...
https://www.biorxiv.org/content/10.1101/2025.09.17.676595v1
4 months ago
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20
10
reposted by
Anna Cusco
Luis Pedro Coelho
4 months ago
Full thread will come later, but
@annacusco.bsky.social
's preprint on the dog pet gut microbiome is out! Using ONT+Illumina, we get better MAGs than to corresponding species representative in public databases
doi.org/10.1101/2025...
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Anna Cusco
bioRxiv Microbiology
4 months ago
Capturing global pet dog gut microbial diversity and hundreds of near-finished bacterial genomes by using long-read metagenomics in a Shanghai cohort
https://www.biorxiv.org/content/10.1101/2025.09.17.676595v1
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reposted by
Anna Cusco
Cameron Thrash
6 months ago
Genome-resolved long-read sequencing expands known microbial diversity across terrestrial habitats
www.nature.com/articles/s41...
#jcampubs
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Genome-resolved long-read sequencing expands known microbial diversity across terrestrial habitats - Nature Microbiology
Nanopore sequencing of Danish soils and sediments yields genomes from over 15,000 microbial species, expanding the phylogenetic diversity of prokaryotes by 8%.
https://www.nature.com/articles/s41564-025-02062-z
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Anna Cusco
Ben J Woodcroft
6 months ago
Out in
@natbiotech.nature.com
: Metagenome taxonomy profilers usually ignore unknown species. SingleM is an accurate profiler which doesn't, even detecting phyla with no MAGs. Profiles of 700,000 metagenomes at
sandpiper.qut.edu.au
. A 🧵
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Anna Cusco
Rossen Zhao
8 months ago
First code release of "SingleM for dsDNA phage"! Lyrebird scans metagenomic reads for marker genes to give a “phage community profile”. It detects many novel phages, many more than standard contig-centric methods.
@benjwoodcroft.bsky.social
@emerge-bii.bsky.social
wwood.github.io/singlem/Lyrebird
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Lyrebird (phage profiling)
Documentation for SingleM
https://wwood.github.io/singlem/Lyrebird
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reposted by
Anna Cusco
Svetlana Ugarcina Perovic
9 months ago
argNorm is published now
academic.oup.com/bioinformati...
add a skeleton here at some point
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reposted by
Anna Cusco
Guillaume Méric
9 months ago
Dominant taxa in microbiomes are obviously important but here's a discussion on low abundance taxa that are highly persisting/prevalent. We can see a lot of these in metagenomics, often obscured by a high false negative rate. 🔗
www.sciencedirect.com/science/arti...
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Anna Cusco
Microbiome Virtual International Forum
10 months ago
#MVIF.37
is LIVE in the Pacific time-zones! Let's talk about Microbiome! The speakers are will be live for Q&A. Join at:
cassyni.com/s/mvif-3
Today's backstage team:
@aroneys.bsky.social
@annacusco.bsky.social
@pamferretti.bsky.social
@azufre451.bsky.social
@kruthirao.bsky.social
@JoseCaparros
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Cassyni | Science starts with a seminar
Seamlessly organise, run and publish academic research seminars. Get started in minutes.
https://cassyni.com/s/mvif-37
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Anna Cusco
10 months ago
We are looking for PhD students! Fully funded studentships available to work on a range of topics, from small proteins to developing computational tools to study the global microbiome
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Anna Cusco
Pam Engelberts
about 1 year ago
Excited to share GenomeFISH: genome-based fluorescence in situ hybridisation for strain-level visualisation of microbial communities.
@sjmcilroy.bsky.social
,
@benjwoodcroft.bsky.social
,
@jamesvolmer.bsky.social
doi.org/10.21203/rs....
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GenomeFISH: genome-based fluorescence in situ hybridisation for strain-level visualisation of microbial communities
Fluorescence in situ hybridisation (FISH) is a powerful tool for visualising the spatial organisation of microbial communities. However, traditional FISH has several limitations, including limited p...
https://doi.org/10.21203/rs.3.rs-5531216/v1
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reposted by
Anna Cusco
Microbiome Virtual International Forum
about 1 year ago
It's Wednesday! ...and
#MVIF
34 program is out! 🤩 ⭐️MicroTalks: 🇹🇼 Ha T. Doan 🇦🇺 Vedanth Ramji ⭐️ Keynote: 🇺🇸 Sean Gibbons
@gibbological.bsky.social
⭐️Selected talks: 🇯🇵 Yuya Kiguchi 🇦🇺 Kurtis Budden 🇨🇭 Amit Halkhoree (#Roche) Registration:
cassyni.com/s/mvif-34
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reposted by
Anna Cusco
Jan Claesen
about 1 year ago
Wow, Bluesky really took off in the last couple of days! The first microbiome starter pack is full now and I started a second one with non-overlapping profiles. Check out these people below and please let me know if you would like to be included!
go.bsky.app/6vPBEty
add a skeleton here at some point
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Anna Cusco
Jan Claesen
about 1 year ago
Hi everyone, I tried assembling a Microbiome & friends starter pack. 🦠🧫🔬 Still learning to use bluesky and might have missed you, let me know if you would like to be included.
go.bsky.app/Fq36egy
add a skeleton here at some point
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Anna Cusco
Binning Singletons
over 1 year ago
I made a starter pack to help recent emigrees from Twitter If you're on it and don't want to be I will happily remove you
go.bsky.app/H5k2p2g
add a skeleton here at some point
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reposted by
Anna Cusco
Luis Pedro Coelho
over 1 year ago
Why are bioinformatics results so full of false positives? I've been thinking about this for a few years: the incentives in the field are to produce false positives
luispedro.substack.com/p/why-are-bi...
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Why are bioinformatics results so full of false positives?
It's what the incentives
https://luispedro.substack.com/p/why-are-bioinformatics-results-so
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reposted by
Anna Cusco
Svetlana Ugarcina Perovic
about 1 year ago
Hey
#AMR
people, the argNorm preprint is now available on
#QUT
ePrints:
eprints.qut.edu.au/252448
We* designed a tool for normalizing ARG annotations across currently popular tools & dbs. *@svetlanaup.bsky.social Vedanth Ramji Hui Chong Yiqian Duan Finlay Maguire
@luispedrocoelho.bsky.social
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reposted by
Anna Cusco
Roland Hatzenpichler
almost 2 years ago
Please share: Are you a data creator/user in
#metagenomics
or other
#omics
? We’re working on standards for fair data reuse and would like your feedback. We welcome contributions by scientists from all career stages. 5-min anonymous survey here:
tinyurl.com/y5kwytpd
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Survey: “A roadmap for fair reuse of public microbiome data”
This survey will inform a manuscript titled “A roadmap for fair reuse of public microbiome data”, the abstract of which and core figure (Figure 1) are included below. The manuscript in its current...
http://tinyurl.com/y5kwytpd
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reposted by
Anna Cusco
Luis Pedro Coelho
almost 2 years ago
New experiment: I will work on a project (starting question: what antibiotic resistance genes co-occur in genomes/metagenomes and does it matter?) completely in the open Everyone is welcome!
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Extremely Open Science Part 1 : introduction
#science #presentationLuis Pedro Coelho introduces the Extremely Open Science Project for 2024Links:- https://www.big-data-biology.org/extremely-open-science...
https://youtu.be/0aX6b9z5uNo
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reposted by
Anna Cusco
Luis Pedro Coelho
about 2 years ago
New preprint: A catalogue of small proteins from the global microbiome! As part of our ongoing efforts to understand small proteins in prokaryotes, we catalogued almost 1 billion sequences!
www.biorxiv.org/content/10.1...
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A catalogue of small proteins from the global microbiome
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
https://www.biorxiv.org/content/10.1101/2023.12.27.573469v1
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Anna Cusco
Ran Blekhman
about 2 years ago
More diverse microbiome communities provide protection against infection, but how? New paper in Science shows this is achieved by nutrient blocking -- diverse communities will consume all the nutrients an incoming pathogen needs to colonize
www.science.org/doi/10.1126/...
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Anna Cusco
Luis Pedro Coelho
about 2 years ago
New release of argNorm This is a little tool to map ARG (antibiotic resistance gene) annotations from different tools to the same common ontology (ARO from CARD)
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GitHub - BigDataBiology/argNorm: ARG normalization by mapping to the ARO ontology.
ARG normalization by mapping to the ARO ontology. Contribute to BigDataBiology/argNorm development by creating an account on GitHub.
https://github.com/BigDataBiology/argNorm/
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