Claire McCarthy
@clairem402.bsky.social
📤 2921
📥 4864
📝 782
scientist with a PhD in toxicology | views are my own
#1song2Versions
2️⃣✖️
#MusicChallenge
🎶
@suoradellanotte.bsky.social
🗣 Bob Dylan 🔊 All Along the Watchtower 🗣 Jimi Hendrix 🔊 All Along the Watchtower
add a skeleton here at some point
about 1 hour ago
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Choose your top 25 favorite comic book adaptations (live action or animated). One per day for 25 days, in no particular order. No explanations, no reviews. Day 2: The Dark Knight
add a skeleton here at some point
about 1 hour ago
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Choose 31 of your favorite songs from animated films, one per day in no particular order. Day 10: Almost There
youtu.be/ThMwHKfzz1I
add a skeleton here at some point
about 1 hour ago
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Claire McCarthy
Alice Ting
3 days ago
Can we design mutations that bias proteins towards desired conformational states? Today in
@science.org
, we introduce Conformational Biasing (CB), a simple and scalable computational method that uses contrastive scoring by inverse folding models to identify conformation-biasing mutations.
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Computational design of conformation-biasing mutations to alter protein functions
Conformational biasing (CB) is a rapid and streamlined computational method that uses contrastive scoring by inverse folding models to predict protein variants biased toward desired conformational sta...
https://www.science.org/doi/10.1126/science.adv7953
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Claire McCarthy
Nature
1 day ago
Researchers are targeting dormant tumour cells that might explain why some cancers reappear long after successful treatment
go.nature.com/4sxSygV
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Why cancer can come back years later — and how to stop it
Nature - Researchers are targeting dormant tumour cells that might explain why some cancers reappear long after successful treatment.
https://go.nature.com/4sxSygV
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Claire McCarthy
Nature
1 day ago
Neither jellyfish nor sea anemones have brains. But these animals sleep in ways strikingly similar to humans
go.nature.com/4juumIa
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Jellyfish sleep like humans — even though they don’t have brains
Nature - Studying ancient sea creatures’ snoozing habits could shed light on the origins of sleep.
https://go.nature.com/4juumIa
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Claire McCarthy
Nature
about 24 hours ago
This artificial skin, inspired by octopuses, can change its colour and surface texture on demand
go.nature.com/3YtuwGn
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Octopus-inspired ‘synthetic skin’ changes colour and texture on demand
Nature - A material that can switch its appearance, cephalopod-style, could have future applications in robotics or display technology.
https://go.nature.com/3YtuwGn
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Claire McCarthy
Carl Zimmer
about 2 hours ago
UCSF scientists build brain organoids at scale equipped with blood vessels, "leading to high fidelity neurodevelopment." Preprint:
www.biorxiv.org/content/10.6...
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Claire McCarthy
Museum of Science
about 24 hours ago
How does an LED light change when dipped in liquid nitrogen? 💡🧪 Museum Educator Adelaide plunges an LED into liquid nitrogen and watches its color shift from orange to yellow to green.
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Liquid Nitrogen LED Experiment: Watch the Color Change!
YouTube video by Museum of Science
https://youtube.com/watch?v=Yz7Qdt9jvqs
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Drop some BOWS!
add a skeleton here at some point
about 2 hours ago
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Claire McCarthy
Admirable Women
about 21 hours ago
Physicist/chemist Katharine Burr Blodgett invented non-reflective glass in 1938. It revolutionized optics & led to the coatings used today in everything from eyeglasses to phone screens. First woman to earn a PhD in
#physics
from Cambridge, 1926. She was born
#OTD
in 1898.
#WomenInSTEM
#inventor
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Drop some TABLES 🏓 🖤 🍽️
add a skeleton here at some point
about 2 hours ago
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Claire McCarthy
Compound Interest | Chemistry infographics
about 7 hours ago
Today is #NationalMilkDay 🥛 Why is milk white, and what makes it go sour over time? This graphic explains:
www.compoundchem.com/2018/06/02/milk
#NationalMilkDay
#ChemSky
🧪
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Claire McCarthy
Scientific American
about 2 hours ago
The number 2026 is, mathematically, more interesting than it appears
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Why 2026 Is a Mathematically Special Number
Neither a square nor prime number, 2026 is still intriguing
https://www.scientificamerican.com/article/why-2026-is-a-mathematically-special-number/
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Choose your top 25 favorite comic book adaptations (live action or animated). One per day for 25 days, in no particular order. No explanations, no reviews. Day 1: Wonder Woman
add a skeleton here at some point
1 day ago
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Choose 31 of your favorite songs from animated films, one per day in no particular order. Day 9: You’ve Got a Friend in Me
youtu.be/1MPZRcyTrcU
add a skeleton here at some point
1 day ago
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Claire McCarthy
Admirable Women
1 day ago
Rachel Carson's book 𝘚𝘪𝘭𝘦𝘯𝘵 𝘚𝘱𝘳𝘪𝘯𝘨 (1962) documented how DDT led to thin eggshells & reproductive failure in predatory birds like bald eagles. It led to the 1972 US DDT ban, sparked environmental awareness & helped bald eagles recover from near-extinction.
#WomenInSTEM
It's Save the Eagles Day!
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Drop some WHEELS 🚙 🏎️ 🖤 🚛
add a skeleton here at some point
1 day ago
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Claire McCarthy
The Atlantic
1 day ago
In its second season, “The Pitt” refuses to both-sides issues that it considers straightforward.
@sophiegilbert.bsky.social
on the rarity of moral clarity in recent TV:
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‘The Pitt’ Is a Brilliant Portrait of American Failure
The HBO Max show has a moral clarity that’s hard to find of late on television.
https://bit.ly/4ptIXoJ
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Claire McCarthy
Compound Interest | Chemistry infographics
1 day ago
January is #InternationalBloodDonorMonth. What makes blood types different and which are compatible with which? Learn more with this graphic:
www.compoundchem.com/2018/01/12/b...
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Choose 31 of your favorite songs from animated films, one per day in no particular order. Day 8: You’re Welcome
youtu.be/79DijItQXMM
add a skeleton here at some point
2 days ago
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Claire McCarthy
Carolyn Bertozzi
2 days ago
Exciting new work from
@aliceyting.bsky.social
and coworkers
@stanfordbiosci.bsky.social
@stanfordmedicine.bsky.social
www.science.org/doi/10.1126/...
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Computational design of conformation-biasing mutations to alter protein functions
Conformational biasing (CB) is a rapid and streamlined computational method that uses contrastive scoring by inverse folding models to predict protein variants biased toward desired conformational sta...
https://www.science.org/doi/10.1126/science.adv7953
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Claire McCarthy
The Washington Post
2 days ago
Review: HBO’s “The Pitt” deservedly emerged as an Emmy darling this past year. And the second season proves that the show understands its strengths — and its limits.
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Review | ‘The Pitt’ takes a deep breath and nails its second act
Rather than compete with the high drama of the first season, the Emmy-winning medical series starring Noah Wyle refocuses on everyday crises.
https://wapo.st/4sLHTj4
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Claire McCarthy
Michael Greshko
4 days ago
🧪 EXCLUSIVE 🧪 from
@science.org
: Scientists have swabbed a 500-year-old drawing attributed to Leonardo da Vinci—and may have found a piece of his DNA.
www.science.org/content/arti...
Yes, really. A quick thread:
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Exclusive: Have scientists found Leonardo da Vinci’s DNA?
Inside the decadeslong quest to reveal the genes of a genius—and revolutionize art authentication
https://www.science.org/content/article/have-scientists-found-leonardo-da-vinci-s-dna?utm_campaign=Science+Magazine&utm_medium=ownedSocial&utm_source=linkedin
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Claire McCarthy
Science Magazine
3 days ago
You don’t need a brain to benefit from a good night of sleep. Despite lacking a central nervous system, jellyfish and sea anemones have sleep patterns remarkably similar to those of humans, researchers report. Learn more:
https://scim.ag/3NgeAEQ
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Claire McCarthy
Nature Portfolio
5 days ago
Nature Medicine asks leading researchers to name their top clinical trial for 2026, from vaccines for infectious diseases to new treatments for advanced cancers and long COVID.
#medsky
🧪
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Eleven clinical trials that will shape medicine in 2026 - Nature Medicine
Nature Medicine asks leading researchers to name their top clinical trial for 2026, from long-awaited vaccines for infectious diseases to new treatments for advanced cancers and long COVID.
https://go.nature.com/3MEpbt0
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Claire McCarthy
Cancer Cell
3 days ago
Online Now: The ADAPT learning cancer treatment system: ARPA-H’s initiative to revolutionize cancer therapy
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The ADAPT learning cancer treatment system: ARPA-H’s initiative to revolutionize cancer therapy
ADAPT is a nationwide initiative to transform cancer care by detecting and responding to tumor evolution in real time. Integrating multimodal data, interpretable AI, and an evolutionary clinical trial platform, ADAPT predicts emerging resistance traits and guides treatment adjustments as tumors change. A unified national infrastructure enables continuous learning across patients, linking discovery directly to care. By making therapy responsive to tumor changes, ADAPT delivers a scalable model designed to improve outcomes in precision oncology.
http://dlvr.it/TQDqZd
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Claire McCarthy
Nature
4 days ago
This artificial skin, inspired by octopuses, can change its colour and surface texture on demand
go.nature.com/44WUbuD
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Octopus-inspired ‘synthetic skin’ changes colour and texture on demand
A material that can switch its appearance, cephalopod-style, could have future applications in robotics or display technology.
https://go.nature.com/44WUbuD
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Claire McCarthy
Nature
3 days ago
Nature research paper: Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit
go.nature.com/45m7t4b
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Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit - Nature
Integrated single-cell and spatial data analysis, combined with bidirectional CRISPR screens, identify the transcription factor GLIS3 as a key driver of chronic inflammation and fibrosis and a potential marker of disease severity in patients with ulcerative colitis.
https://go.nature.com/45m7t4b
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Choose 31 of your favorite songs from animated films, one per day in no particular order. Day 7: A Whole New World
youtu.be/EXTLJmYsaUQ
add a skeleton here at some point
3 days ago
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Claire McCarthy
Nature Methods
3 days ago
iGluSnFR4f and iGluSnFR4s are the latest generation of genetically encoded glutamate sensors, for tracking rapid dynamics and for recording from large populations of synapses.
www.nature.com/articles/s41...
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Claire McCarthy
Fabian Theis
3 days ago
🔬 pertpy: a unified, scalable framework for single-cell perturbation analysis, now out in Nature Methods Designed for modern perturbation data - CRISPR, drug screens, patient treatments - scaling to millions of cells and 1000s of conditions. 👉
www.nature.com/articles/s41...
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Share some walkie talkies, radios, stereos
add a skeleton here at some point
3 days ago
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Claire McCarthy
Scientific American
3 days ago
Sea anemones and jellyfish don’t have brains, but the way their neurons behave during sleep shows some surprising similarities to humans
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Scientists Catch Jellyfish and Sea Anemones Behaving in Surprisingly Human Ways
Sea anemones and jellyfish don’t have brains, but the way their neurons behave during sleep shows some surprising similarities to humans
https://www.scientificamerican.com/article/jellyfish-and-sea-anemones-sleep-just-like-us/
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C&EN (Chemical & Engineering News)
3 days ago
In a recent study, researchers used honey from native Brazilian bees as a solvent to extract bioactive compounds from cocoa bean shells, a waste product of making cocoa and its derivatives.
cen.acs.org/food/food-sc...
#chemsky
🧪
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Honey from Brazilian bees used as solvent for cocoa compounds
The flavorful 'chocolate honey' could also lead to more-sustainable natural products
https://cen.acs.org/food/food-science/honey-brazil-bees-solvent-chocolate/104/web/2026/01?sc=260108_sc_eng_bs_cen
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“When you get to know people who are different from you, you begin to learn more about yourself. You change. You grow.”
#StrangerThings
#WednesdayWisdom
4 days ago
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Choose 31 of your favorite songs from animated films, one per day in no particular order. Day 6: Be Our Guest
youtu.be/DtCEI9SDtqQ
add a skeleton here at some point
4 days ago
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Claire McCarthy
Waggoner Lab
5 days ago
Review
@natrevcancer.nature.com
Opportunities and challenges of targeting cGAS–STING in cancer
www.nature.com/articles/s41...
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Opportunities and challenges of targeting cGAS–STING in cancer - Nature Reviews Cancer
In this Review, Lu et al. discuss the dual role of the cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS)–stimulator of interferon genes (STING) pathway in cancer, emphasizing...
https://www.nature.com/articles/s41568-025-00894-9
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Claire McCarthy
Christian Zierhut
5 days ago
Excited to announce a new review article that Andreas Villunger
@villungerlab.bsky.social
, Dario Rizzotto (not on bsky) and I wrote. In this article, we discuss mitosis as a central cell cycle stage for integrating DNA damage, cell death and inflammatory responses.
www.nature.com/articles/s41...
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Mitotic errors as triggers of cell death and inflammation - Nature Cell Biology
Rizzotto et al. discuss the causes and consequences of deregulated mitosis that allow cells arrested in mitosis to escape to the next interphase, where they can initiate inflammatory signalling or und...
https://www.nature.com/articles/s41556-025-01785-9
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Claire McCarthy
Lucy Penrose
4 days ago
#Booksky
www.bbc.com/culture/arti...
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The 40 most exciting books to look forward to in 2026
From big-name authors Colson Whitehead, George Saunders and Maggie O'Farrell to debuts and non-fiction, these are the titles you'll want to add to your reading pile this year.
https://www.bbc.com/culture/article/20260106-the-40-most-exciting-books-to-look-forward-to-in-2026
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Claire McCarthy
Nature
6 days ago
Nuclear fusion. People on Mars. Artificial general intelligence. These are just some of the advances that could come by 2050
go.nature.com/4slEUO5
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Science in 2050: the future breakthroughs that will shape our world — and beyond
Nuclear fusion. People on Mars. Artificial general intelligence. These are just some of the advances that could come by the mid-century mark.
https://go.nature.com/4slEUO5
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Claire McCarthy
Nature
6 days ago
Book review 📚 These women helped to shape quantum mechanics — it’s time to recognize them
go.nature.com/3Ls2yYu
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These women helped to shape quantum mechanics — it’s time to recognize them
An astute book redresses our collective perception of a field that became known as ‘boys’ physics’.
https://go.nature.com/3Ls2yYu
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Claire McCarthy
Nature
5 days ago
Neither jellyfish nor sea anemones have brains. But these animals sleep in ways strikingly similar to humans
go.nature.com/4prixUM
loading . . .
Jellyfish sleep like humans — even though they don’t have brains
Studying ancient sea creatures’ snoozing habits could shed light on the origins of sleep.
https://go.nature.com/4prixUM
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Choose 31 of your favorite songs from animated films, one per day in no particular order. Day 5: A Dream is a Wish Your Heart Makes
youtu.be/cyOLHOcLdr4
add a skeleton here at some point
5 days ago
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Claire McCarthy
Elizabeth McKenna
5 days ago
Now online in Cancer Discovery
@aacrjournals.bsky.social
: LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture - by Michael Lee, Yuannyu Zhang, Jian Xu, and colleagues
doi.org/10.1158/2159...
@stjuderesearch.bsky.social
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Claire McCarthy
Stacey Ogden 🦔
5 days ago
Woo hoo! 🎉 Shout out to
@stjuderesearch.bsky.social
postdoc Christina Daly for her featured image on FocalPlane! ✅ the link for more about her research interests! 🧪 🔬 🤩 👩🔬🙌
#Microscopy
#DevBio
#Neurodevelopment
#Cytonemes
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Claire McCarthy
Amanda Heidt
5 days ago
🧪 I've been deep in the cancer space in recent months, including this feature, out in the most recent issue of
@nature.com
, on cancer dormancy and how it can lead to metastasis decades after a person has ostensibly been declared cancer-free.
www.nature.com/articles/d41...
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Why cancer can come back years later — and how to stop it
Researchers are targeting dormant tumour cells that might explain why some cancers reappear long after successful treatment.
https://www.nature.com/articles/d41586-025-04149-3
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“Sometimes your bravest journey is the first step.”
@charliemackesy1.bsky.social
#MondayMotivation
6 days ago
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Choose 31 of your favorite songs from animated films, one per day in no particular order. Day 4: Let It Go
youtu.be/YVVTZgwYwVo
add a skeleton here at some point
6 days ago
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Claire McCarthy
The Open Notebook
6 days ago
New year, new you? We recently published our writer’s guidelines as a resource for any writer or editor interested in improving their craft, from how to tackle common writing pitfalls to how to navigate fact-checking. Here they are, free for any journalist anywhere. 🧪
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The Open Notebook’s Writers’ Guidelines - The Open Notebook
Landing an assignment, especially a feature, is an exciting moment for any early-career journalist. But what happens next in the reporting, writing, and editing phases can sometimes be ambiguous. This...
https://www.theopennotebook.com/writers-guidelines/
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