Moss Powering the Next Drug Frontier Chinese hamster ovary (#CHO) cells have been the gold standard for producing biologic drugs. Now, an unlikely contender—#moss—is offering a new path forward. #pharma #biopharmaceutical #nextgeneration www.genengnews.com/topics/biopr...

Amazing to see one week regenerating P. patens transformed with big DNA carrying a mCherrry, can’t wait for the genotyping soon and full genome sequencing afterwards #plantsyntheticgenomics

Finally I had a look to my Phytobricks ecosystem that I have been building as part of my research on plant synthetic biology now genomics. Looks like I have some hubs, perhaps already some signs of scale free network? #plantsyngenomics #moss #synPACs #beyondrecoding

Technical thread on why Liu et al.'s Cell Reports doi.org/10.1016/j.ce... paper validates some of our Urquiza-Garcia et al 2025 model predictions published in Molecular Systems Biology doi.org/10.1038/s443... 🧵

Systemic and local regulation of root growth by vascular trehalose 6-phosphate is correlated with re-allocation of primary metabolites between shoots and roots https://www.biorxiv.org/content/10.1101/2025.11.13.688188v1

Our #cryoET of #plasmodesmata preprint is out! Will write more on it later. 🌿❄️

Bringing back to life some 10 year old constructs I did during my PhD CCA1pro:NanoLUC-PEST

🎊 We made it!! @dfg.de has just announced that we have been successful with our CEPLAS III proposal in the current funding round of the Excellence Strategy! Many thanks to all our supporters! @hhu.de @unicologne.bsky.social @mpipz.bsky.social @fz-juelich.de @leibnizipk.bsky.social

@ceplas.bsky.social continues!! Let’s continue delivering excellent plant research now SMARTe plants in dynamic environments!

Moose – Die Gamechanger der Medizin und Forschung! Mein Interview für #FrischeFische auf YouTube. #Exzellenzinitiative #Moose #Medizin #Evolution #Forschung #scicomm #wisskomm @cibss.bsky.social #livMatS @biologyunifreiburg.bsky.social www.youtube.com/watch?v=JzgL...

Finally! Im so excited to present to culmination of many years of work from the fantastic Defeng Shen and some great collaborators. For details, I have made a digested thread below, but if you are more interested feel free to reach out (and read the paper of course). www.science.org/doi/10.1126/...

After a lot of work, we are finally able to share this project about the cell cycle in Marchantia from the Haseloff lab. If you want to find out how cell division is controlled, you can’t miss out this one… #PlantScience #Synbio #EvoDevo www.biorxiv.org/content/10.1...

If you are looking for published plant genomes www.plabipd.de/pubplant_mai... might be useful where Rainer is tracking species with genomes for almost 10 years now... time flies. As he has added new useful views, we thought it is time to summarize this. www.biorxiv.org/content/10.1...

Our updated preprint now on bioRxiv: Production of human papillomavirus type 16 virus-like particles in #Physcomitrella photobioreactors www.biorxiv.org/content/10.1...

Laura Trimborn, [...] and Ute Hoecker CRY1 inhibits the activity of COP1 by competitively displacing substrates from COP1 pubmed.ncbi.nlm.nih.gov/40052249/

Our new review in @theplantjournal.bsky.social on synthetic gene circuits is out! I am super proud of this. I hope that it acts as a useful resource for people new to gene circuits. The switch-liker's guide to plant synthetic gene circuits onlinelibrary.wiley.com/doi/10.1111/...

I’m happy to share that I will join the LIT in Regensburg (lit.eu) as a Group Leader in Structural Biochemistry in May. We will combine synthetic biology and protein design to develop synthetic receptors and protein therapeutics to improve immunotherapy. Job openings will be available soon!

My first students in Plant Synthetic Genomics put together a nice tool for biodesign automation of random DNA fragments for synthetic genomics applications. "Gearing up Golden Braid assembly for plant synthetic genomics with RepTiles" @hhu.de @ceplas.bsky.social www.biorxiv.org/content/10.1...

Hey can y'all check to see if the NCBI blastn page is working? Genbank page seems down, too. Same on your end? TYIA www.ncbi.nlm.nih.gov/genbank/

Is it my imagination or #NCBI is down? cannot access it from Germany

Abundant clock proteins point to missing regulation in the plant circadian clock www.embopress.org/doi/full/10.... first experimental determination of the abundance of transcription factors in Plants and for the circadian clock. It was such a challenge but finally out after peer review !!!

After becoming the 2nd FRS to quit over Elon Musk, @andrewmillar.bsky.social explains why Musk's actions "are not compatible with the conduct required of a fellow...they undermine the purpose of the Royal Society" The @royalsociety.org has called fellows to a 3rd March meeting as the crisis grows

@andrewmillar.bsky.social has resigned from the #RoyalSociety I hope others follow

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

Insighful review from André Marques nph.onlinelibrary.wiley.com/share/5UPJFE...

#Tomorrow @uni-freiburg.de: panel discussion on the pros and cons of #GreenGeneTech. Join us for an exciting discussion! 👉 kurzlinks.de/twhu @friasunifreiburg.bsky.social@[email protected]@[email protected]@[email protected]

I wonder when will DNA be a commodity like electricity

Abundant clock proteins point to missing molecular regulation in the plant circadian clock. Urquiza-García et al 2024; study by @andrewmillar.bsky.social bioRxiv doi.org/10.1101/2024.09.03.609973 #preprintpeerreview by Review Commons eeb.embo.org/doi/10.1101/2024.09.03.609973.

A step by step protocol for absolute quantification of protein using Arabidopsis thaliana transgenic lines carrying NanoLUC-tagged genes www.protocols.io/view/a-step-...