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🎙️ Today on Endpoints News Post-Hoc Live, we're talking about Sarepta. @drewsnews.bsky.social will be joined at 1:30pm ET by @jaredwhitlock.bsky.social and @leileiwu.bsky.social about the company's showdown with the FDA over its #duchennegenetherapy. Watch live here: endpoints.news/endpoints-li...

Join us at 1130am ET today for our latest Post-Hoc Live stream, to talk about Trump's "most favored nation" drug price plan. Executive editor @drewsnews.bsky.social and Nick Shipley talk about how the executive order works (or doesn't) and what happens next. www.youtube.com/live/7qGP5Ge...

I've been trying to do this chat for YEARS and am so glad we are finally making it happen. Come for the health policy, stay for the GameStop story.

If you are going to the FT Pharma and Biotech summit on Thursday, please come drop by my session where I'll be chatting with @drewsnews.bsky.social about my lil cancer, and some other fun things. uspharma.live.ft.com/agenda

Elon Musk said DOGE made a mistake by cutting USAID’s Ebola prevention but it had been “restored.” That’s not true, current and former officials told me and @johnphudson.bsky.social. “There have been no efforts to ‘turn on’” Ebola prevention, said Nidhi Bouri, who oversaw team until January.

Kudos to the @endpts.com team for not running away from this issue like everyone else.

Exclusive: Drugmakers plan Trump meeting next week amid Washington health shakeups, via @drewsnews.bsky.social endpts.com/drugmakers-p...

Well, as I said a couple of weeks ago, thank God I'm not a CEO and I don't have to do this sort of dirty work. Because let's not kid around: if it has to do with the intersection of business and the Trump administration as it's been running so far, it's going to end up being dirty.

Kennedy made promises that he'll be a moderate on vaccines, and then Trump blew them up. endpts.com/trump-underc...

🏈📺This Hims Super Bowl ad leans very hard into the "pharma bad" / MAHA angle. Looks like these guy are picking a fight (in part over compounding, but swinging bigger than that) with pharma: www.youtube.com/watch?v=l5l6...

We're a week out from Endpoints News at #JPM2025, and the agenda is fantastic! We'll talk through the Trump transition, AI's year ahead, John Carrol will lead chats on cancer and dealmaking, and more. If you don't have a ticket, I've got a discount 😉> JPM25_10 events.endpts.com/jpm25/697639...

Tirzepatide shortage is over, says FDA. That means compounding pharmacies making lots of copies of brand-name Zepbound and Mounjaro have to stop soon. endpts.com/in-blow-to-c...

⬆️⬇️ It's here! Biopharma's winners, losers, featuring a 🐴 endpts.com/endpoints-wi...

...Pain trials are hard (so is anything w/ patient self-scoring) ...And placebo problems are real ...But this is a result that could kill a program or even a company at little biotech. (Vertex has the $$ + rep for Ph3 to find out if they're right.) endpts.com/vertexs-non-...

The @endpts.com JPM agenda is LIVE. This is going to be next-level. We've got Jennifer Doudna, Scott Gottlieb, Hal Barron, Eric Tokat, Janet Woodcock, Steve Hahn and many, MANY more huge names... events.endpts.com/jpm25/agenda

PBM reform... it's happening? endpts.com/major-pbm-re...

If you're an @endpts.com subscriber, you may have recently seen a note in your inbox from @drewsnews.bsky.social. The TLDR is that many of us are here, on this site, giving you the biopharma and health care news you need. Give us a follow! Give us feedback! I always want to hear how we can improve.

Just finding us here? Endpoints News has a starter pack with our journalists so you can follow the team! go.bsky.app/NzDRUhL

I wrote about covering a shooting a 13 years ago, how the medium of the moment distorts violence in strange ways, and the strange, worrying moment we're in with the killing of an insurance executive. endpts.com/post-hoc-wha...

Scoop with @kylelahucik.bsky.social and @drewsnews.bsky.social: There's a changing of the guards atop a16z's health and biotech team. Vijay Pande is handing over the reins to Vineeta Agarwala as he prepares for a larger role involving AI in healthcare. endpts.com/vijay-pande-...

Good story from @drewsnews.bsky.social with JPM about a month away endpts.com/insurance-ex...

A great follow on rare disease, diagnostics and cool tech:

UnitedHealth has confirmed the shooting and death of insurance group head Brian Thompson in Manhattan this morning. They've (obviously) canceled investor day. Completely shocking. endpts.com/ceo-of-unite...

OMG -- $UNH exec Brian Thompson (leads insurance business) shot and killed in Manhattan, the Post is reporting. Citing police saying it may have been a targeted attack. Totally shocking. nypost.com/2024/12/04/u...

Lilly released it's head-to-head with Wegovy today and it appears to have a meaningful edge on long-term weight loss (handy chart from Liz Cairns)

And... we've got an Endpoints News starter pack! Join up! go.bsky.app/NzDRUhL

Interesting spot by @maxbayer.bsky.social -- Eli Lilly has dropped BMI from the label for its weight loss drug Zepbound. endpts.com/lilly-remove...

We're starting to compile this year's Endpoints 2024 Winners + Losers list.... Got ideas? DMs are open. Be clever, be brief. endpts.com/biotech-and-...

This is the furthest @scottgottliebmd.bsky.social tt (who ran the FDA during Trump 1.0) has gone in criticizing Trump's pick for HHS.

Former FDA Commissioner Scott Gottlieb opposed President-elect Donald Trump’s choice to lead the Department of Health and Human Services, saying RFK Jr.’s policies would lead to a resurgence of preventable diseases and cost lives, @drewsnews.bsky.social reports. endpts.com/former-fda-h...

🟨😎🟦 AAHAHAHHAHAHAHAHAHAHAHAHAHAHAHAH

Loved this Odd Lots from @tracyalloway.bsky.social + @weisenthal.bsky.social on Medicare fraud. A great primer for anyone interested in govt fraud/abuse, with a nice dose of DME, dialysis + ambulance shenanigans. podcasts.apple.com/us/podcast/h...

Little transition scooplet -- the Trump team asked **Warp Speed leader Moncef Slaoui** about running the NIH last week @andrewedunn.bsky.social reports. Slaoui said no. endpts.com/trump-team-a...

👀Warp speed mention in surgeon general announcement...

Breaking: Florida's top health official calls for an end to fluoride in state's drinking water. Joseph Ladapo, Florida's surgeon general who has been bidding for a spot in Trump admin, cites controversial studies about the risk of fluoride to developing brains. w @fenitn.bsky.social

NEW w/ @adamcancryn.bsky.social: At least 3 antivax activists are helping RFK Jr. recruit and vet candidates for top jobs at HHS. While the Trump transition argues they're not part of the official process, they're calling themselves the 'MAHA transition team.' www.politico.com/news/2024/11...

Really interesting story about how chemistry + law affect markets: Eli Lilly is trying to get its next weigth-loss drug classified as a biologic. Why? To avoid the threat of compounding pharmacies. The crux of the case is a single amino acid: endpts.com/drug-or-biol...

RFK and Elon Musk have said they'd like to ban DTC drug ads. The ads aren't popular, and are controversial. But many have tried, and almost all have failed, to force changes. endpts.com/could-trump-...

I for one am glad that every journalist who did their time writing the once-every-five-years RUC explainer might finally get their moment in the sun.

A starter pack of biotech founders curated by Jason Kelly— the co-founder and CEO of Ginkgo Bioworks #biosky

Hi new followers. I'm Drew Armstrong, the Executive Editor of Endpoints News (endpts.com). I post about biotech, pharma, VC, science, markets + healthcare policy.

It looks like Sage's last big neuro bet has failed. The company is now trading for less than the cash on its books. It has no other midstage or advanced programs in the works. endpts.com/sage-reports...

Dr Oz from the FOIA files, courtesy of @zacharybrennan.bsky.social endpts.com/internal-tru...

Dr Oz for CMS. Okay then!

Interesting piece from @scottgottliebmd.bsky.social on the GLP-1 compounding debate. I'm not sure how you put this back in the bottle -- big market, major cost debate. Feels like a one-way street...

My app for finding 🦋 accounts you may want to follow has had a make-over: it now displays names and bios, and allows adding an "app password" for direct follow buttons in the listing bsky-follow-finder.theo.io

Some very interesting names in this @politico.com report on possible Trump admin health picks: * The Means siblings in senior roles (Casey potential Surgeon Gen, Calley in a top deputy role -- but neither at FDA) * CDC, NIH possibles www.politico.com/news/2024/11...

Started creating a synthetic biology starter pack. Still missing many so reply here if I forgot you or someone else. go.bsky.app/SjfpxTK #synbio

📣This is always VERY interesting. If you're a biopharma CEO (public or private) and want to be included, DM me. We are working on a few exclusive benefits for respondents.