🎉Just appeared online in #JCTC @pubs.acs.org "Improving Conformational Ensembles of Folded #Proteins in #GōMartini" @maksimkalutskii.bsky.social @maxotubule.bsky.social @carterjwilson.bsky.social pubs.acs.org/doi/10.1021/...

BioEmu is now on @science.org ! The revised version includes an upgraded model and makes a lot of MD simulation data internally generated at MSR available to the public. This took a lot of firepower from us in the last two years. www.science.org/doi/10.1126/...

New publication out on the evolution of protein-RNA interactions. Put together with Klára Hlouchová (@sciencecharles.bsky.social) during a lovely Czech spring. www.sciencedirect.com/science/arti...

📌Carter @carterjwilson.bsky.social‬ is presenting (P-2.44) "A Tale of Two #Aquaporins: Structural Mechanisms of Gating and Inhibition in Aqp3 and Aqp7" and + 📌Florian will explain (P-2.196) "How Loop #Dynamics Control Activity and Selectivity of a Short Chain #Reductase" Happy discussions! 👥

Have a great D2@ #EBSA2025 in Rome🫠! Here are the posters of today's session: 📌Maksim @maksimkalutskii.bsky.social is presenting (P-2.195) his project addressing #Microtubule Dynamics Are Defined by Conformations and Stability of Clustered #Protofilaments 📜🔗 www.pnas.org/doi/10.1073/...

🚨 JOB ALERT 🚨 We're hiring a Research Assistant – no PhD needed! Join us to explore the molecular mechanisms of receptor sorting in endosomes. Experience in protein expression/purification, cloning & cell culture desired 🧫🔬 Apply now 👉 www.nature.com/naturecareer... #STEMCareers #ResearchJobs

the magic growing/shrinking GTP/GDP switch lies in the differential ability to bend out of plane and hold on neighbours. Alone you go faster, together we go further.

Happy to contribute to this fantastic work by @maksimkalutskii.bsky.social and @maxotubule.bsky.social! www.pnas.org/doi/abs/10.1...

( #TubulinTuesday! )

UK immigration policy is destabilising international academics’ careers. The effort of staying compliant with fluctuating regulations diminishes the mental space for teaching, research and building belonging, say Zahra Sharifonnasabu et al www.timeshighereducation.com/opinion/uk-i...

📜 Great work by Maksim and Co-authors! Congratulations to this latest #microtubule #publication in @pnas.org 🍾 @maxotubule.bsky.social @maksimkalutskii.bsky.social @vladimirvolkov.bsky.social

Excited to share our latest work in @pnas.org! Combining simulations and cryo-ET, we reveal how microtubules decide between growth and shortening. doi.org/10.1073/pnas... @maksimkalutskii.bsky.social @vladimirvolkov.bsky.social @compbiophys.bsky.social @mpi-nat.bsky.social @qmul.ac.uk @dundee.ac.uk.

Our joint paper with Wonpil Im lab is now available as a preprint: "Dynamic Architecture of Mycobacterial Outer Membranes Revealed by All-Atom Simulations" www.biorxiv.org/content/10.1...

Excited to share our latest work in @pnas.org! Combining simulations and cryo-ET, we reveal how microtubules decide between growth and shortening. doi.org/10.1073/pnas... @maksimkalutskii.bsky.social @vladimirvolkov.bsky.social @compbiophys.bsky.social @mpi-nat.bsky.social @qmul.ac.uk @dundee.ac.uk.

🚀 First Bluesky Post! 🎉 VMD 2.0 Alpha is here! Released today at BPS 2025, this is the biggest update in 30 years—new UI, real-time ray tracing, fast surfaces, UHD & touchscreen support. Monthly updates coming in 2025! Try it now! #VMD #BPS2025 #MolecularVisualization www.ks.uiuc.edu/Research/vmd...

Yean Ming Chew and I wrote doi.org/10.1042/BST2... about MT lattice switching. We discuss evidence that protofilament-level structural switching is ancient and fundamental and conserved; and that tubulation creates new allosteric interfaces that operate on essentially the same structural switch.

The regular registration for on-site participation has been closed. However, it is still possible to join our workshop online! You find the link to the according registration on our workshop website 🔗https://www.mpinat.mpg.de/workshop/huenfeld #TheoryHünfeld2025 #biophysics

We have a PhD position in Molecular chemical physics at UCT Prague, Czechia. It is closely related to our research of the evolution of #protein-RNA interactions. A pre-PhD #internship available from January 2025. Apply directly by email to [email protected].

The inside of a cell is incredibly crowded! With advancing computing power and smart algorithms, this complex world is becoming more accessible through simulations. This review summarizes the current state of modeling macromolecular crowding: pubs.acs.org/doi/10.1021/... #CompChem

🎉 I'm starting my own lab at EMBL-EBI (Cambridge, UK; June 2025) 🎉 We will focus on identifying and characterizing chemical hazards to humans and ecosystems using computational biology methods. I am beginning the search for two postdocs now - stay tuned for more details! ewaldlab.org

Do not miss our latest #cryoET work! 🕵️ Xing et al. present the dynamic architecture of TRiC in human cells! The study of this protein-folding chaperonin opens the door to understanding its dysfunction in diseases like cancer and neurodegeneration 🧠🧪 #teamTOMO @becklab.bsky.social

Want to engage with the #mechanobiology community? Why not join this group? Just drop me a DM and I´ll add you. go.bsky.app/G5cQqYT

Couldn't find one so made a quick physics of life list, enjoy! go.bsky.app/EA2VsDN

In this work, we use all-atom MD simulations to elucidate why human and rhesus macaque TRIM5α differ in their ability to restrict HIV. See our manuscript by Liam Haas-Neill, Deniz Meneksedag-Erol & Ibraheem Andeejani --

Extended until the 17th of Dec

Friends don't let friends make bad graphs repo has been updated! Friends don't let friends use boxplot for binomial (bimodal) data. Is your box plot hiding something from you? #DataVisualization github.com/cxli233/Frie...

🚨 PLEASE REPOST 🚨 We're still looking for an enthusiastic PhD student 😉 Here are some potential projects: - mechanical stability of microtubules probed by computational force spectroscopy - mechanism of microtubule assembly studied by coarse-grained modeling www.mpinat.mpg.de/28-24?c=2501...

The Spring School in Computational Chemistry 2025 is open for registration 🗓️ 23-25 April 2025 🌐 Espoo, Finland Further info and registration ➡️ bit.ly/41phwUJ #compchem #hpc #Training #moleculardynamics #machinelearning Organised together with CSC - IT Center for Science and @eurocc.bsky.social

Bluesky feels like the biggest speed dating event at a conference ever.

One week left to apply for this job!! I'm looking for a research tech to come and work on Alzheimers and ApoE! If you love cell culture, astrocytes, APOE or just fun science with fun people then come do science with us in beautiful Dundee! tinyurl.com/a33kjn49 Seriously the sunsets are on point!

Very happy to receive a Wellcome CDA! The award will fund my lab for a whopping 8 years, allowing us to dissect force-sensing at the kinetochore-microtubule interface in depth using structural methods. We are currently looking for a postdoc: qmul-jobs.tal.net/vx/candidate... Please apply or repost

📢 It's our great pleasure to invite you all to our upcoming #Workshop on "Computer Simulation and #Theory of Macromolecules" in #Hünfeld on March 7-8, 2025 in #hybrid format! See you online or on-site! More details are provided here: www.mpinat.mpg.de/workshop/hue... #TheoryHünfeld2025 #biophysics

🚨 PLEASE REPOST 🚨 We're still looking for an enthusiastic PhD student 😉 Here are some potential projects: - mechanical stability of microtubules probed by computational force spectroscopy - mechanism of microtubule assembly studied by coarse-grained modeling www.mpinat.mpg.de/28-24?c=2501...

BTW we‘ve recently released an improved version of our manuscript uncovering the assembly mechanism of microtubules via intermediate clusters of protofilaments! @maksimkalutskii.bsky.social @vladimirvolkov.bsky.social @compbiophys.bsky.social 👇👇👇 doi.org/10.1101/2024...

What is the difference between a growing and shortening microtubule end? I thought I knew the answer until I started talking to Maxim Igaev and Maksim Kalutskiy. Turns out the key are protofilament clusters - check out our new preprint for details www.biorxiv.org/content/10.1...

Open up and dance 🕺🏻

BTW we‘ve recently released an improved version of our manuscript uncovering the assembly mechanism of microtubules via intermediate clusters of protofilaments! @maksimkalutskii.bsky.social @vladimirvolkov.bsky.social @compbiophys.bsky.social 👇👇👇 doi.org/10.1101/2024...