Now online in Cancer Discovery @aacrjournals.bsky.social: Screening for Tumor Microtube-Targeting Drugs Identifies PKC Modulators as Multipotent Inhibitors of Glioblastoma Progression - by Daniel Azorín, Dirk Hoffmann, @winklerlab.bsky.social, and colleagues doi.org/10.1158/2159...

#Glioblastoma cells don’t just grow — they extend tumor microtubes that let them invade the brain 🧠 and link into multicellular networks that resist therapy ☢️. We developed a strategy to inhibit these TMs — and make these cells vulnerable to therapy ☠️. This study is now online @Cancer Discovery

As part of the call for applications below, the Heidelberg/Mannheim site is offering four clinician scientist/postdoc positions in the field of neuro-oncology in the departements of @wickwolfgang.bsky.social and @michael-platten.bsky.social. For applications use the link below.

The 2025 Nobel Prize in Physiology or Medicine was awarded jointly to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.” This Collection celebrates the award and recognizes the winners’ achievements. #medsky 🧪

Excited to share our latest work in Neuro-Oncology Advances! 🥳 After comparing several potential therapies, we identified lamotrigine as a promising therapy for NF1 optic glioma, showing both tumor reduction and vision protection. Check out the work of our great team!

The amazing Ms. Mary Stallings at @jazzstlouis.bsky.social. Absolutely wonderful!

Happy to share the review out in @cp-cellreports.bsky.social Thanks to amazing Sebastien Talbot and Alexander Birbrair www.sciencedirect.com/science/arti...

We are still welcoming submissions for our exciting special issue on #InVitroModels of #HumanDisease. We're looking forward to receiving your next paper by 3 November 2025. Editors: @vivianlilab.bsky.social, @ausmith.bsky.social & Joseph Wu #OpenAccess #DiseaseModelling #CallforPapers

Congrats to CSHL's @jborniger.bsky.social and team NEUROIMPACT on making the @cancergrand.bsky.social finals! Their research, showing how the nervous system detects and responds to cancer, could point to new ways of treating the deadly disease. #CancerNeuroscience www.cshl.edu/borniger-rea...

Music at the Intersection #MATI in St. Louis!

CSHL recently hosted its 4th annual tree-lighting to honor Pediatric Cancer Awareness Month. The tree-lighting is a reminder to our entire community that we remain stronger when we work together against childhood cancer.

🚨 Registration deadline for the EACR conference on #cancerneuroscience is September 15 ‼️ Please join us in beautiful Bilbao for exciting discussions on the dialogue between the nervous system and cancer 🔬🧠 See you soon!

📢 We are excited and honored to announce that Frank Winkler received #thebrainprize2025, together with @michellemonje.bsky.social, for pioneering the field of #cancerneuroscience. 💐 @brainprize.bsky.social #neuroscience #cancer brainprize.org

David Baltimore, giant of molecular biology, has died.

A Review by Frank Winkler & @matthiakarreman.bsky.social on how neural-cancer interactions shape metastasis and tumor evolution www.cell.com/neuron/fullt...

We are proud to present a Special Issue on Cancer Neuroscience, curated by editors Bennie Babayan & Ted Dobie. This issue offers a snapshot of the field through a collection of Perspectives, Reviews, and NeuroViews: cell.com/neuron/issue.... See below for details on the pieces:

Exciting news! Our new paper is out in Neuron! We discovered how neurons drive brain tumor growth through aberrant glutamate–tyrosine kinase signaling, uncovering novel mechanisms that shape tumor progression. Grateful to our team & collaborators for making this breakthrough possible! 🧠✨

Time traveled back to the 1920s at the Focal Point with T J. Muller and band.

Thank you for another amazing experience at the @newportjazzfest.bsky.social this year. Sunday was otherworldly!

We are so proud of Rasha and Rui's new paper! Their single cell reveals hidden diversity in CD8+ exhausted T cells across cancers, shedding light on why patients respond differently to immunotherapy and bringing us closer to more effective therapies. Don’t miss this exciting advance from our team!

We were thrilled to welcome Girl Scout Troop 222 to the lab this week! They explored science hands-on and got a glimpse of the work we do. Grateful for their curios minds and amazing energy—let’s keep inspiring the next generation of scientists! 🔬💫 #GirlsInSTEM #Troop222

This past weekend we celebrated the 3rd Annual NF Family Day - a special time to honor our patients and families, build community, and have fun! From shaved ice and giant slides to visits from the St. Louis Fire and Police Department, we’re grateful for the support and another year moving forward.

Today we celebrated two incredible members of the Gutmann lab. We'll miss Alex’s cooking tips and Talia’s humor, but we’re excited for all that lies ahead on their next adventures!

Happy July 4th weekend. #forestparkforever.

I could not be more fortunate and proud to work with such a great group of people.

Cholinergic neuronal activity promotes diffuse midline glioma growth through muscarinic signaling: Cell www.cell.com/cell/fulltex...

Music to my ears. #haroldlopeznussa @thenextset.bsky.social @jazzstlouis.bsky.social

Join us for a free informational webinar for medical students, graduate students, residents, fellows or postdocs to learn about exciting opportunities in the multidisciplinary field of neuro-oncology. Tuesday June 10, 2025, at 6:00 pm ET Register today! bit.ly/4jsVmX5

We will be attending #ISSCR2025. Visit the @biologists.bsky.social booth in the exhibition hall for giveaways and to learn about grants and events, and be sure to reach out to Dina Mikimoto with any questions you might have about publishing with us. @isscr.org

This week we have said, "See you later" (never goodbye) to an incredible lab member! Chloe has brought joy and amazing work to the lab since her undergrad for more than 4 years. We wish her the best in NYC and her journey to med school.

So appreciative to Children's Hospital of Atlanta and Emory University for inviting me to deliver a keynote talk at their Pediatrics symposium. Wonderful venue, stimulating discussions, and always great to see of friends.

The end of an era in @gutmannlab.bsky.social. Best wishes to the future Dr. Chloe Kernan.

Happy June 1st. Forest Park Forever.

Still hard to wrap ones brain around.

Russell Gunn & Blackhawk at @jazzstlouis.bsky.social. Amazing evening of quartet music.

RIP Norm. One of a kind. www.npr.org/2025/05/20/n...

Science, sport, and resilience come together on Nov 19. CSHL honors Chris Evert, Martina Navratilova, and Dr. Bob Langer at the Double Helix Medals dinner—our biggest night for research. www.cshl.edu/cshl-to-hono...

We are so happy to have our friends from Penny's Flight Foundation visit last week! It was wonderful sharing the exciting NF1 research currently happening in the lab. We're so grateful for their dedication to raising NF awareness, supporting patients, and championing research. #nf1 🦋

Hit by Trump tariffs, a rubber duck museum is migrating to Canada to stay afloat www.npr.org/2025/05/10/n...

Great evening at @jazzstl.bsky.social with Mr. James Carter.

Tonight at Jazz St. Louis The James Carter Organ Trio brings raw energy, soul, and virtuosity to JSL! Watch live on YouTube now: www.youtube.com/live/4SeWeIC... #JamesCarter #OrganTrio #JazzStLouis #FerringJazzBistro #LiveJazz #JazzOrgan #SoulJazz #ModernJazz #STLJazz #JazzOnline #YouTubeLive

#MusicSky #MayTheFourth

Vintage cars at the St. Louis Art Museum. Just off Route 66.

Gilbert Family Foundation for science. #NF1.

Susan Werner at the Sheldon in St. Louis tonight. Great concert.

Fantastic to have Dr. Erin Gibson from Stanford here at WashU. Super seminar today!

Today, we celebrate the journey of two amazing trainees in the lab. They have great things coming into their future, and we are equally sad and proud to see them go. Wherever their paths may take them, the Gutmann lab will always be their home. Good luck, Laura and Xuanwei!