As part of our 2025 “Rising Stars in #Vaccinology and #Immunity to #Microbes” seminar series, we spoke with Dr. Daniel Wrapp @wrapplab.bsky.social who uses structure-based design to develop new #antiviral therapies. cvimp.podbean.com/e/episode-13...

Our latest preprint is now available doi.org/10.1101/2025...! Led by my postdoc, Luqiang Guo @luqiang.bsky.social, we determined a ~2.4 A resolution structure of the hantavirus glycoprotein tetramer on the surface of VLPs. Also determined structures of dimers of tetramers and Fab-bound tetramers.

Design, Structure, and Immunogenicity of a Soluble Prefusion-stabilized EBV gB Antigen www.biorxiv.org/content/10.1101/2025.05.19.654955v1 #cryoem

Very excited to share our latest preprint describing the isolation and characterization of neutralizing HCoV-229E-directed antibodies from a human donor! Great collaboration between DHVI and the Baric and Sheahan (@timothysheahan.bsky.social) labs at UNC. www.biorxiv.org/content/10.1...