Our new preprint on #SARSCoV2 nsp14 #exonuclease function in replication fidelity and fitness. ExoN- viruses are attenuated in vitro and in vivo but w/o #interferon signaling replication is largely restored! Suggests nsp14 plays a role in innate antagonism in vivo www.biorxiv.org/content/10.6...

Human coronavirus 229E antibodies and Spike structure function paper is finally out for real. Led by @wrapplab.bsky.social (wrappers delight) and @mlicc1701.bsky.social (MFL) #lovevirology #229E #antibodies www.nature.com/articles/s42...

New #coronavirus #postacute lung pathogenesis paper from my friend Dr. John Powers is up at @asm.org JVI. journals.asm.org/doi/10.1128/... Confusing as to why this link shows a rotund blue bird. #PASC #SARSCoV2 #Omicron #LoveVirology #JVI #ASM #virology

Grant writing w ballet rehearsal on the side. #coronavirus #exonuclease is cool shit. Guides replication fidelity and we think masterminds control of the host response. Oh my. If only my 12 pages were done? #grantwriting #acadreamia #nih #coronavirus

New paper about ACE2 using Merbecovirus. Hot stuff. So hot but you can't Letko. @fviromics.bsky.social and Nick Catanzaro. www.nature.com/articles/s41... #ACE2 #emergingviruses #bats #batman #MERS #HKU5

@mattfrieman.bsky.social taped this to my lab notebook almost 20 years ago. It’s not untrue 🤣Vestiges of simpler times. #lovevirology #virology #lablife #sars #laboratory #science #biology #academia

So nice to be teamed up with @wrapplab.bsky.social on this mAb project! It's been a delight. Some may say a Wrapper's Delight? #antibodies #virology #lovevirology #229E #coronavirus #therapeutics #vaccination #emergingviruses

Having a hard time processing this. HHMI is pausing all competitions. Very demoralizing for early career scientists like me @hhmi.org

How much federal research funding has been axed so far in the new administration? An early estimate is $1.8B, but that's likely an underestimate, @aniloza.bsky.social reports. www.statnews.com/2025/05/08/t...

How does one determine EC50 w a curve like this? #antivirals #coronavirus #cell www.sciencedirect.com/science/arti...

Thank you @holdenthorp.bsky.social for being a voice which eventually we can hopefully build into a chorus. It's hard to not fall into a daily bleakness black hole (DBBH).

NIH has rescinded its scientific integrity policy. Hard to see this as anything other than clearing the way for shoddy research on things like vaccines. Regardless of the rationale, it's bad news for public health. grants.nih.gov/grants/guide...

"Angry, disappointed, frustrated"--Scientists were making progress on vaccines and antivirals for the next pandemic--until this week, when the Trump administration abruptly told them to stop. Here's my story with @apoorvanyt.bsky.social Gift link: nyti.ms/43Xz77q

The damage being done to the biomedical community will probably not be appreciated for years

I just covered this for @thetransmitter.bsky.social — will keep following! www.thetransmitter.org/funding/fede...

Saved from death in the paper grave yard! Started in 2016. MERS-CoV infects epithelial cells, they die, pathology is wicked bad. Adaptive immune cells both control replication and drive pathogenesis. #coronavirus #MERSCoV #pathogenesis #LoveVirology #viruses #virus journals.asm.org/eprint/ZZEIT...

Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring www.science.org/content/arti...

Just when you though Apple’s #Siri was the most annoying and egregiously offensive Siri…https://www.nytimes.com/2024/12/13/health/aaron-siri-rfk-jr-vaccines.html?smid=nytcore-ios-share&referringSource=articleShare&sgrp=c-cb

Excited for my first bluesky post announcing TWO openings for tenure track positions in virology! I am chair of the search committee and with a new department head Mike Gale we are in an exciting building phase. Please share with anyone who might be interested: hr.myu.umn.edu/jobs/ext/365...

Firing forgotten neurons teaching my 12 year old daughter how to plate bacteria and calculate colony forming units! #stem #scienceolympiad #SciOly #cfu #ecoli #lablife #microbiology

Remember #coronaviruses? We need broad antivirals for #emergingviruses. Cool collab w Jim Sacchettini @ Texas A&M on a protease inhibitor #antiviral. HTS, structure guided med chem, in vitro, in vivo assays. www.cell.com/cell-reports...

#Cookie mitosis! Every year I make cookies for the #lab using my kid’s #Halloween haul. Too much damn candy. #lablife #lovevirology #biology #labculture #baking #bakingtherapy

Following in Charlie's footsteps on the snack front because the science = hard 😭. As a #ricelab postdoc @ #rockefeller 10+ years ago there were always snacks to fuel #virology. Now I try to do small things like this for my people to brighten their day. #lablife #traderjoes #charlierice #labculture