Sabrina Schmied
@sabrinaschmied.bsky.social
📤 19
📥 29
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Ph.D. student in Protein Chemistry
@univie.ac.at
in the Becker Lab
reposted by
Sabrina Schmied
Christian A. Olsen
10 months ago
I am extremely happy to share this new
@biorxivpreprint.bsky.social
, which after a long wait updates our previous preprint. Thanks to main drivers
@bgless.bsky.social
and
@benjaminsb.bsky.social
as well as all involved colleagues and collaborators!
www.biorxiv.org/content/10.1...
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reposted by
Sabrina Schmied
Christian A. Olsen
11 months ago
I am delighted to share that this paper is now published as an Editor's Choice article in JACS Au
@pubs.acs.org
pubs.acs.org/doi/10.1021/...
add a skeleton here at some point
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reposted by
Sabrina Schmied
Bengt Gless
11 months ago
I'm excited to share our latest paper reporting an interesting thioester-to-imide acyl transfer reaction of S-acylcysteine. It was great working with
@sabrinaschmied.bsky.social
and
@christianaolsen.bsky.social
#chemsky
#chembio
pubs.acs.org/doi/10.1021/...
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Peptide Backbone Cleavage and Transamidation via Thioester-to-Imide Acyl Transfer
Cysteine thioesters are involved in a myriad of central biological transformations due to their unique reactivity. Despite their well-studied properties, we discovered an unexpected transamidation rea...
https://pubs.acs.org/doi/10.1021/jacsau.4c01143?articleRef=test
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reposted by
Sabrina Schmied
Christian A. Olsen
12 months ago
In a new preprint
@chemrxiv.bsky.social
, work from
@bgless.bsky.social
and Sabrina Schmied investigate the mechanism of a rearrangement that can lead to peptide/protein backbone cleavage. Thanks to
#LEOFondet
for funding the project that led to this discovery.
chemrxiv.org/engage/chemr...
loading . . .
Peptide Backbone Cleavage and trans-Amidation via Thioester-to-Imide Acyl Transfer
Cysteine thioesters are involved in a myriad of cen-tral biological transformations because of their unique reactivity. Despite their well-studied proper-ties, we discovered an unexpected trans-amidat...
https://chemrxiv.org/engage/chemrxiv/article-details/6750257a5a82cea2faf0c9bf
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