Our study with @melnicklab on the discovery of a transient and tightly-regulated, plastic state of mature B cells during physiological immune response and potential links to aggressive lymphomas now out at NCB.👇Detailed threat by the amazing lead author @lscourzic.bsky.social!. .

Epigenetics Update - Postmitotic transcription and 3D regulation show locus-specific and differentiation-specific sensitivity to cohesin depletion go.nature.com/48ISkLD UkJin Lee and @efapostolou29.bsky.social at @weillcornell.bsky.social #Epigenetics #Chromatin --- epigenometech.com

🚀 My lab 3d-chrom.iit.it is recruiting a PhD student within the INT2ACT Marie Curie Network 🌍🧬 If you want to work with epigenetic/epitranscriptomic tools + 3D chromatin assays to study how ncRNAs shape genome organization and gene expression apply to DC12 by Jan 31st int2act.eu/open-positio...

🧬We’re hiring a Senior Bioinformatician @IIT in Genova 🇮🇹 Join our lab 👉 3d-chrom.iit.it to explore how non-coding RNAs shape 3D genome architecture ⏰ Deadline Nov 16th- only a few days left to apply! app.ncoreplat.com/jobposition/...

🚨For chromatin, epigenetics and non-coding RNA lovers: only two more weeks left to apply! Check out our lab page and if interested don't hesitate to apply 3d-chrom.iit.it Research Technician app.ncoreplat.com/jobposition/... Senior Researcher-Technologist app.ncoreplat.com/jobposition/...

🎯 Our lab at the Italian Institute of Technology 3d-chrom.iit.it has a technician position available If you are a scientist, interested in chromatin 🧬 epigenetics and non-coding RNAs and you are looking to work in a stimulating environment don’t hesitate to apply 👇 app.ncoreplat.com/jobposition/...

🚨 Last Call for Applications! 🚨 If you're passionate about chromatin 🧬 and non-coding RNAs, you have only a few days left to apply: Three fully-funded positions in my lab to study the cross-talk between epigenetics and 3D chromatin architecture. Application links are available in the post below 👇

I am so happy to see this work finally out 🎉 authors.elsevier.com/c/1kqIJ_Oylr... Thanks to all the authors for the incredible teamwork!!!

To all chromatin and RNA enthusiasts 🧬 🧬 🧬 Our lab 3d-chrom.iit.it has several openings! Looking for a well-paid position in a stimulating environment? Apply here 👇 Senior Bioinformatician iit.taleo.net/careersectio... Senior Molecular Biology Researcher iit.taleo.net/careersectio...

Here is the peer-reviewed version of our study showing how some TAD borders are essential for gene regulation and development. Loss of a single CTCF motif is sufficient to cause embryonic lethality. www.sciencedirect.com/science/arti...

New preprint from the lab investigating the role of cohesin in the establishment of chromatin loops and transcriptional programs after cell division or during cell fate transitions. Study led by @ukjinlee.bsky.social. Grateful to the whole team and NIH for support!

Together with @smandrup.bsky.social and Minna Kaikkonen we are happy to announce the 3rd Edition of the EMBO Workshop on #Enhancers and #Enhanceropathies. This time we will meet during the beautiful Danish summer (June 16-21). Book the dates and register soon!!! meetings.embo.org/event/25-enh...

Very cool collaboration with @andersshansen.bsky.social's lab on how to calibrate Micro-C using our labs' previous live-cell estimates of looping probability!

We are happy to share our enhancer scramble story, a strategy to create hundreds of stochastic deletions, inversions, and duplications within mammalian gene regulatory regions and associate these new architectures with gene expression levels 🧵 www.biorxiv.org/content/10.1...