Valentina Boeva
@valboeva.bsky.social
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Computational Cancer Genomics Group
reposted by
Valentina Boeva
American Association for Cancer Research (AACR)
6 months ago
#AACRai25
cochairs Valentina Boeva and Benjamin Haibe-Kains adjourned the AACR Conference on AI and Machine Learning. We thank all of the chairs—including
@marzyehghassemi.bsky.social
and
@bowang87.bsky.social
—for developing an outstanding program.
@valboeva.bsky.social
@bhaibeka.bsky.social
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🔥A very cool piece from Alexander Theus and team is finally on arXiv:
arxiv.org/abs/2506.22712
Ever wondered if you can linearly interpolate between transformers and still get a working model? Now you know how. A breakthrough! 🚀
6 months ago
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🚨 New preprint out! We studied deep learning models for high-resolution DNA accessibility prediction from DNA sequence! Key takeaway: ConvNeXt V2 blocks consistently boost accuracy. 📖 Preprint:
biorxiv.org/content/10.1...
đź”—Code:
github.com/BoevaLab/ASAP
📦 pip install atac-asap
7 months ago
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reposted by
Valentina Boeva
Stein Aerts
8 months ago
Our new call for VIB.AI group leaders is online! Junior and senior positions available to develop innovative ML methods in biology. With professorship at CS or Medical Faculty. Deadline 14th June. DM for more info.
add a skeleton here at some point
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Valentina Boeva
Maxim Greenberg
9 months ago
The Americans are doing to Kseniia what the Russians did to Brittney Griner for having 0.7 grams of cannabis oil. Except no one is coming to negotiate her freedom and Harvard is sitting on their hands. I am so ashamed. Please share this story.
www.nytimes.com/2025/04/11/s...
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She Worked in a Harvard Lab to Reverse Aging, Until ICE Jailed Her (Gift Article)
President Trump’s immigration crackdown ensnared Kseniia Petrova, a scientist who fled Russia after protesting its invasion of Ukraine. She fears arrest if she is deported there.
https://www.nytimes.com/2025/04/11/science/russian-scientist-ice-detained-harvard.html?unlocked_article_code=1.-04.ksF9.FzoMjUpj3KeL&smid=url-share
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🥳🔥Our study is out in Genome Biology! Conventional filtering out high-mtRNA cells depletes key malignant populations in cancer single-cell studies. Read it here 👉
genomebiology.biomedcentral.com/articles/10....
Thanks to the dream team: Josephine Yates and Agneizska Kraft!
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Filtering cells with high mitochondrial content depletes viable metabolically altered malignant cell populations in cancer single-cell studies - Genome Biology
Background Single-cell transcriptomics has transformed our understanding of cellular diversity, yet noise from technical artifacts and low-quality cells can obscure key biological signals. A common pr...
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-025-03559-w
9 months ago
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Interested in cutting-edge ML and AI in cancer research? Join us at the AACR Special Conference on Artificial Intelligence and Machine Learning in Montreal, July 10–12, 2025: 🔗
www.aacr.org/meeting/aacr...
⏳ Submit your abstract by April 16, 2025 at 1 p.m. ET!
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AACR Special Conference in Cancer Research: Artificial Intelligence and Machine Learning
Overview for AACR Special Conference in Cancer Research: Artificial Intelligence and Machine Learning
https://www.aacr.org/meeting/aacr-special-conference-in-cancer-research-artificial-intelligence-and-machine-learning/
9 months ago
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reposted by
Valentina Boeva
SIB Swiss Institute of Bioinformatics
11 months ago
🎤 It is a pleasure to welcome Itay Tirosh from the Weizmann Institute at [BC]². Itay will present in the session 'Bioinformatics for cancer research'. 🔹Session chaired by
@valboeva.bsky.social
and
@carmonation.bsky.social
👉Interested? Submit your abstract before 27 Feb:
tinyurl.com/49w6wthj
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reposted by
Valentina Boeva
Samuel Kaski
11 months ago
I have big news:
@ellis.eu
has launched its 2nd major research center,
@ellisfinland.bsky.social
! I have agreed to start as founding director & the first call for PI positions is open. This is a major opportunity for outstanding researchers, join us!
ellisinstitute.fi/PI-recruit
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Principal Investigator positions at ELLIS Institute Finland | ELLIS Institute Finland
Now recruiting new PIs in artificial intelligence and machine learning
https://ellisinstitute.fi/PI-recruit
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Looking forward to meeting the Lausanne AI Center people and giving a talk on predicting enhancer-promoter interactions using our deep ensemble model this Wednesday!
memento.epfl.ch/event/ai-cen...
12 months ago
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Looking forward to presenting our recent (and yet unpublished) work at UNIL/CHUV next Thursday! If you're in Lausanne and would like to meet, ping me—I’ll be around from Tuesday to Friday!
12 months ago
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🌟If you are at
#NeurIPS2024
, stop by our poster on the first single-cell
#cancer
foundation model. Amazing work by
@flobarkmann.bsky.social
and Alex Theus 👇
add a skeleton here at some point
about 1 year ago
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đź“…Are you attending
#NeurIPS2024
and curious about the latest in self-supervised learning (SSL) for biology? - Stop by our poster on applying SSL on single-cell data: SSL workshop on Saturday! Work by amazing team of
@oovcharenko.bsky.social
, P. Toma, Imant D., J. Vogt and
@flobarkmann.bsky.social
add a skeleton here at some point
about 1 year ago
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reposted by
Valentina Boeva
bioRxiv Biophysics
about 1 year ago
A mathematical model clarifies the ABC Score formula used in enhancer-gene prediction https://www.biorxiv.org/content/10.1101/2024.11.29.626072v1
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A mathematical model clarifies the ABC Score formula used in enhancer-gene prediction https://www.biorxiv.org/content/10.1101/2024.11.29.626072v1
Enhancers are discrete DNA elements that regulate the expression of eukaryotic genes. They are impor
https://www.biorxiv.org/content/10.1101/2024.11.29.626072v1
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reposted by
Valentina Boeva
TomĂ s Montserrat Ayuso
about 1 year ago
Not checking nuclear markers like MALAT1 or intronic reads in your scRNA-seq data?🚨 We show their power to flag low-quality cells—even in top public datasets. It’s time to prioritize better QC for cleaner, more reliable genomics research! Read more:
bmcgenomics.biomedcentral.com/articles/10....
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High content of nuclei-free low-quality cells in reference single-cell atlases: a call for more stringent quality control using nuclear fraction - BMC Genomics
The advent of droplet-based single-cell RNA-sequencing (scRNA-seq) has dramatically increased data throughput, enabling the release of a diverse array of tissue cell atlases to the public. However, we...
https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-024-11015-5
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🚀 New preprint from our lab, Ekaterina Krymova, and
@fabiantheis.bsky.social
: UniversalEPI, an attention-based method to predict enhancer-promoter interactions from DNA sequence and ATAC-seq🌟 Read the full preprint:
www.biorxiv.org/content/10.1...
by
@aayushgrover.bsky.social
, L. Zhang & I.L. Ibarra
about 1 year ago
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Should now we start doing it for whole human tumors?!
add a skeleton here at some point
about 1 year ago
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reposted by
Valentina Boeva
Dominic GrĂĽn
about 1 year ago
Hiring! I'm looking for a postdoc in machine learning of spatial single-cell data. Exciting project to develop methods for modelling cellular circuits in disease and regeneration of heart, liver and bone marrow using Xenium data from our lab.
tinyurl.com/ymkvk7vn
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reposted by
Valentina Boeva
Sten Linnarsson
about 1 year ago
Before I go to bed let me post an amazing paper by Filipe Pereira’s group (Ervin Ascic et al) for your enjoyment. I think this is a likely fundamental breakthrough in cancer immunotherapy: personalized, yet generic and probably pan-cancer.
www.science.org/doi/10.1126/...
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In vivo dendritic cell reprogramming for cancer immunotherapy
Immunotherapy can lead to long-term survival for some cancer patients, yet generalized success has been hampered by insufficient antigen presentation and exclusion of immunogenic cells from the tumor ...
https://www.science.org/doi/10.1126/science.adn9083
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