Tamal Das
@tamaldastifrh.bsky.social
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Associate Professor at TIFR Hyderabad; Exploring the collective dynamics of cells in biology.
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We study what organelles do - beyond their "textbook" functions - during development and wound healing. Here is a story on how ER morphology shapes cells' response to wound curvature 👇
add a skeleton here at some point
10 months ago
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reposted by
Tamal Das
Nature Cell Biology
10 months ago
☕🍰Interested in reading more about the study? Here is the N&Vs article written by Roberto Mayor. 👉https://rdcu.be/eJqR1
bit.ly/3IEA38F
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Forcing cell fate - Nature Cell Biology
The transition of a pluripotent stem cell into a differentiated lineage is one of the most complex yet precisely orchestrated events in developmental biology. A study now reveals that mechanical and osmotic forces, long considered background players in guiding this transition, are essential regulators of chromatin accessibility and cell fate decisions.
https://bit.ly/3IEA38F
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reposted by
Tamal Das
Nature Cell Biology
9 months ago
🎃Our October issue's out! Cover: mechanoresponsive
#microtubules
👉🏼Reviews:
#CellularStress
;
#NuclearPoreComplex
&
#mechanobiology
🔬
#StemCells
#senescence
#cancer
#EndoplasmicReticulum
#phagocytosis
#pyroptosis
#autophagy
#PhaseSeparation
#AMPK
#chromatin
& more!
www.nature.com/ncb/volumes/...
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reposted by
Tamal Das
Fabian Spill
10 months ago
Thanks Craig Blackstone for the news & views
@natcellbio.nature.com
about our article thats shows how ER shape and mechanics determine the mode of cell migration. Collaboration with Simran, Pradeep and
@tamaldastifrh.bsky.social
.
rdcu.be/eJZWf
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ER shaping closes the gap in wound healing
Nature Cell Biology - During wound healing, epithelial gaps trigger curvature-dependent ER remodelling. Tubules form at convex cell edges and promote lamellipodial crawling, whereas ER sheets at...
https://rdcu.be/eJZWf
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reposted by
Tamal Das
Sarah Cohen
10 months ago
Wonderful to see our paper on the
#organelle
signatures of
#neurons
and
#astrocytes
out in final form - congratulations, Shannon Rhoads and team!🎉
t.co/BPxKlbU6Ou
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reposted by
Tamal Das
Fabian Spill
11 months ago
Great collaboration on uncovering how ER organisation, curvature and mechanics are regulating collective cell migration. Experiments by Simran, Tamal and collaborators and a model by Pradeep.
add a skeleton here at some point
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We study what organelles do - beyond their "textbook" functions - during development and wound healing. Here is a story on how ER morphology shapes cells' response to wound curvature 👇
add a skeleton here at some point
10 months ago
0
1
0
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