Tamal Das
@tamaldastifrh.bsky.social
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Associate Professor at TIFR Hyderabad; Exploring the collective dynamics of cells in biology.
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We study what organelles do - beyond their "textbook" functions - during development and wound healing. Here is a story on how ER morphology shapes cells' response to wound curvature 👇
add a skeleton here at some point
4 months ago
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reposted by
Tamal Das
Nature Cell Biology
3 months ago
☕🍰Interested in reading more about the study? Here is the N&Vs article written by Roberto Mayor. 👉https://rdcu.be/eJqR1
bit.ly/3IEA38F
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Forcing cell fate - Nature Cell Biology
The transition of a pluripotent stem cell into a differentiated lineage is one of the most complex yet precisely orchestrated events in developmental biology. A study now reveals that mechanical and osmotic forces, long considered background players in guiding this transition, are essential regulators of chromatin accessibility and cell fate decisions.
https://bit.ly/3IEA38F
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reposted by
Tamal Das
Nature Cell Biology
3 months ago
🎃Our October issue's out! Cover: mechanoresponsive
#microtubules
👉🏼Reviews:
#CellularStress
;
#NuclearPoreComplex
&
#mechanobiology
🔬
#StemCells
#senescence
#cancer
#EndoplasmicReticulum
#phagocytosis
#pyroptosis
#autophagy
#PhaseSeparation
#AMPK
#chromatin
& more!
www.nature.com/ncb/volumes/...
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reposted by
Tamal Das
Fabian Spill
3 months ago
Thanks Craig Blackstone for the news & views
@natcellbio.nature.com
about our article thats shows how ER shape and mechanics determine the mode of cell migration. Collaboration with Simran, Pradeep and
@tamaldastifrh.bsky.social
.
rdcu.be/eJZWf
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ER shaping closes the gap in wound healing
Nature Cell Biology - During wound healing, epithelial gaps trigger curvature-dependent ER remodelling. Tubules form at convex cell edges and promote lamellipodial crawling, whereas ER sheets at...
https://rdcu.be/eJZWf
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reposted by
Tamal Das
Sarah Cohen
4 months ago
Wonderful to see our paper on the
#organelle
signatures of
#neurons
and
#astrocytes
out in final form - congratulations, Shannon Rhoads and team!🎉
t.co/BPxKlbU6Ou
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reposted by
Tamal Das
Fabian Spill
4 months ago
Great collaboration on uncovering how ER organisation, curvature and mechanics are regulating collective cell migration. Experiments by Simran, Tamal and collaborators and a model by Pradeep.
add a skeleton here at some point
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We study what organelles do - beyond their "textbook" functions - during development and wound healing. Here is a story on how ER morphology shapes cells' response to wound curvature 👇
add a skeleton here at some point
4 months ago
0
1
0
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