@drmichelleboyle.bsky.social
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reposted by
Science Magazine
about 1 month ago
The approved medication ruxolitinib dampens inflammatory responses to malaria and can enhance immune memory to the parasite in infected volunteers, supporting its potential as an adjunctive therapy to improve outcomes.
#ScienceTranslationalMedicine
https://scim.ag/44tu6TB
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Adjunctive ruxolitinib attenuates inflammation and enhances immunity in volunteers experimentally infected with Plasmodium falciparum
Adjunctive ruxolitinib reduces inflammatory response after experimental malaria challenge and enhances immune memory responses to reinfection.
https://scim.ag/44tu6TB
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reposted by
Science Magazine
about 2 months ago
This week's issue of
#ScienceTranslationalMedicine
has arrived! A transcriptional signature could inform smarter antibiotic use in newborns with sepsis, an approved medication boosts anti-malaria immunity in volunteers, and more.
https://scim.ag/43PsmE6
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So pleased to share our study of a host-directed therapy to boost malaria immunity. Adjunctive ruxolitinib attenuates inflammation and enhances immunity in volunteers experimentally infected with Plasmodium falciparum | Science Translational Medicine
www.science.org/doi/10.1126/...
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Adjunctive ruxolitinib attenuates inflammation and enhances immunity in volunteers experimentally infected with Plasmodium falciparum
Adjunctive ruxolitinib reduces inflammatory response after experimental malaria challenge and enhances immune memory responses to reinfection.
https://www.science.org/doi/10.1126/scitranslmed.aea2531
about 2 months ago
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reposted by
Joanna Groom
8 months ago
Excited to have our latest research published in
@jem.org
this week and also highlighted by
@natrevimmunol.nature.com
@wehi-research.bsky.social
@benjbroom.bsky.social
add a skeleton here at some point
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