As a final nod to 2025, #GeneOntology announces our latest paper in @narjournal.bsky.social! Updates include expanded #Ontology & annotations in #Metabolism, multi-org interactions, #chromatin remodeling, & more. Also ft. #Functionome v2 and 1500+ GO-CAM pathway models! 🧬🧪 doi.org/10.1093/nar/...

❄️ Gene Ontology Winter Break ❄️ Our resources will remain fully accessible through the holiday season: release.geneontology.org. Support requests will be addressed after we return on January 5th. Wishing our wonderful community a restful season and a well-annotated 2026! 🧬✨

👏 Congratulations 🎉 to PhD student Daiqing Chen for her #PosterAward at @amsocmatbio.bsky.social for "The MatriGO Project: Systematic Curation and Refinement of ECM-related Terms in #GeneOntology" #UIC #MatrixBiology #Science

From a farm in the north of England to the frontiers of bioinformatics, our Group Leader Sandra Orchard reflects on a career building the data foundations of modern biology: “AI is showing how vital data curation really is.” www.ebi.ac.uk/about/news/p... 🖥️🧬

Only a week until the next Alliance webinar, this month it will be on MicroPublications. Make sure you're registered now!

We identified many differentially expressed genes and found differences in gene ontology processes between groups. Genes involved in cell cycle regulation were enriched in miniature taxa, while genes associated with growth factors and tissue development were enriched in large-bodied gobies.

GONNECT: A Gene Ontology-guided Neural Network for Explainable Cancer Typing https://www.biorxiv.org/content/10.1101/2025.11.06.686983v1

#LiteratureNotice Patel & Kumar. Functional complexity of Parthenium beetle, #Zygogramma bicolorata (Pallister) under thermal-stress conditions: Insights from Gene Ontology. doi.org/10.1016/j.as... #Beetle #Beetles #Mexicanbeetles #Calligrapha

It's #InternationalSnowLeopardDay. Check out GO's new October release for Unica unica #GOannotations, as well as over 9.4 million other annotations for other organisms! More information about the release on the @alliancegenome.bsky.social Forums: community.alliancegenome.org/t/8546

Reminder to everyone that's attending our in-person meeting next month- registration fees are due! Make your dinner choices and pay your meeting fees now. Check your email for both links!!

For anyone out there that might be hiring, we have absolutely loved working with @drglam.bsky.social and everyone at the Harvard FB and can't recommend them enough! This is not only devastating to the staff directly affected, but also to the entire science community.

Did you register for the upcoming GOC meeting yet? Less than a month left to get the group rate on lodging! Details: community.alliancegenome.org/t/fall-2025-...

New GO data just out!! The July 2025 GO Release 2025-07-22 is now available. ➡️ current.geneontology.org ➡️ release.geneontology.org/2025-07-22 📓 DOI 10.5281/zenodo.16423886: doi.org/10.5281/zeno... 39,906 GO terms 9,417,935 annotations 1,602,275 gene products 5,497 species

Already bored of summer? Not to worry, a new GO Release is here! current.geneontology.org release.geneontology.org/2025-06-01 10.5281/zenodo.15611813 40,122 GO terms 9,395,247 annotations 1,602,165 gene products 5,495 species

It's started! If you're not in Geneva right now you're missing out on the 2025 Spring GOC Meeting! If you've registered to attend remotely, please check your emails for links. Recordings will be available to GOC members and registered guests shortly after the meeting.

Updated preprint by Agneesh Barua agneeshbarua.bsky.social on convergence and pleiotropy in teleost fish gene evolution, with lots of new results! www.biorxiv.org/content/10.1...

Last chance to register for the upcoming Spring GOC Meeting! To all Consortium members, if you're planning on coming in-person to the meeting next month in Geneva, remember to register today! Check your email for the registration link, agenda, and hotel info.

You know about the PAN-GO #Functionome, but have you explored the power of the Functional Category search? Learn how to find #humangenes of interest in just a few clicks, using the Functional Categories community.alliancegenome.org/t/8362 🧬🧪 #GOSlims ICYMI: community.alliancegenome.org/t/8343

The PAN-GO #Functionome was announced last week in @nature.com-but do you know how to use it? Here's how to find functions for a selected human #gene: ➡️ community.alliancegenome.org/t/8353 ICYMI, more on the PAN-GO Functionome: 💡 community.alliancegenome.org/t/8343 🧪🧬 #science #research #human

THE PAN-GO #FUNCTIONOME IS LIVE! Read our brand new #openaccess @nature.com paper and explore the PAN-GO Functionome, our most accurate and complete resource ever! Paper links, press release, how to contribute and more on the @alliancegenome.bsky.social Forums: community.alliancegenome.org/t/8343

Is that love in the air? Yes! You'll LOVE this news- the February 2024 GO Release [2025-02-06](release.geneontology.org/2025-02-06/i...) is now available! [http://release.geneontology.org/2025-02-06](release.geneontology.org/2025-02-06) [10.5281/zenodo.14861039](doi.org/10.5281/zeno...)

The Spring 2025 GOC Meeting will be May 6-8 in Geneva! Will you be there? Registration details were sent out to all GOC members, check your email!

Wishing everyone a safe and happy holiday season! Although our downloads and products should be available over the break, we will not have any staff available to address any enquiries until January 5th. We look forward to seeing you all when we return in January 2026!

It's time to start thinking about New Year's Resolutions. But what's one of the easiest ways to be healthier in the New Year? Why, by making sure your GO data is healthy! Read more on the @alliancegenome.bsky.social forum: community.alliancegenome.org/t/go-start-t...

It's getting chilly; a familiar scent is in the air- but it's not pumpkin spice, it's the smell of a fresh new GO Release! The Nov GO Release is out in the wild & ready to party! current.geneontology.org release.geneontology.org/2024-11-03 Full deets: community.alliancegenome.org/t/november-2...

Did you know there are different ontology files, and the relations (and tool compatibility) varies between them? Read more on the @alliancegenome.bsky.social Forums: community.alliancegenome.org/t/relations-...

GO traditionally focused on protein-coding genes, but a new publication by Antonazzo et al. highlights the recent expansion of ncRNA annotation. Definitely worth reading for both researchers and curators! community.alliancegenome.org/t/expansion-...

❓ GO puts the FUN in function, yes - but what is phenomenal for phenomics??? ➡️ uPheno! Read more about the fantastic Unified Phenotype Ontology here: community.alliancegenome.org/t/ever-neede...

Attention GO Consortium members: if you haven't yet registered or submitted topics of interest for the October GOC meeting, time is running out! Check your emails or the GO Wiki for links. GOC Fall 2024 Meeting is Tuesday, Oct 15th- Thursday, Oct 17th & will be virtual.

Welcome all new users! It's not just 🦋 that's rapidly gaining users-the @alliancegenome.bsky.social is too! The Alliance, of which GO is a founding member, will have a live webinar on September 19th: An Introduction to the Alliance". Register by Sep 18th! community.alliancegenome.org/t/webinar-an...

Ever see a #GeneOntology annotation that doesn't use a PMID as a reference, but instead has GO_REF: and a bunch of numbers? Find out what a GO_REF is & where to find full descriptions of them in this week's Alliance Forums post: community.alliancegenome.org/t/whats-a-go...

Do you work with chicken data? Do you know about GEGA, and how it combines GO with other database information? Read more at the @alliancegenome.bsky.social forums: community.alliancegenome.org/t/gega-gallu... Access GEGA at gega.sigenae.org

Lead contamination is a danger to us all. Even if you test your water, it can still be in the food you eat. Han et al. identify flavonoid metabolism as important in the response to lead stress in maize- more at @alliancegenome.bsky.social Forums: community.alliancegenome.org/t/go-and-lea...

Cancer research progresses every day. In a new paper from Huang et al, there is a novel prognostic signature that may help predict immunotherapy response- and they use GO to help their research: community.alliancegenome.org/t/go-and-lun...

Most #GeneOntology annotations propagate up the #ontology- but do you know how to identify ones that do NOT? Read more on the @alliancegenome.bsky.social Forum: community.alliancegenome.org/t/transitivi...

Do you use GO GPAD files? Although mostly used for internal purposes, if you use GPAD files please be aware the format is getting an update to GPAD 2.0 and this is a breaking change. Details at community.alliancegenome.org/t/go-file-fo...

Liquorice can be divisive-some love it, others hate it. However, it has known medicinal qualities. Ma et al. use #GO (and #omics) to evaluate the potential #medicinal value of a rare wild liquorice and show the importance of preserving #biodiversity 🧪 community.alliancegenome.org/t/go-and-rar...

Forgot to register for Quest for Orthologs 2024? Registration AND abstract submission dates have been extended to May 14!! Act now and join QFO8 in Montreal this July 17-18, right after ISCB's ISMB: event.fourwaves.com/qfo8/pages

Don't be the weak link! If you link to GO terms, GO_REFs, GO-CAMs, or the ontology, make sure you're using PURLs. Read more: community.alliancegenome.org/t/best-pract... 🧪

Best way to celebrate #itsgonnabemay? A bonus GO release to wrap up April! Details for the new, second April release (2024-04-24): 🧪 community.alliancegenome.org/t/second-apr...

Holy Pathways, Batman! Did you know you can find GO-powered Pathways on @alliancegenome.bsky.social pages? community.alliancegenome.org/t/go-cams-on...

Happy #DNADay2024! 🧬 Today's @alliancegenome.bsky.social forum post highlights some of the close ties between the Human Genome Project and the #GeneOntology: both Dr. David Botstein and Dr. Paul Thomas. community.alliancegenome.org/t/happy-dna-... 🧪

(GO) annotation, the Transporter Classification Database tcdb.org and publications. (we've reviewed and updated GO annotation to be more accurate and to provide better coverage). TRANSMEMBRANE TRANSPORTERS are divided into four major classes: @geneontology.bsky.social

Rice, wheat, bamboo, maize... the Poaceae family is immense. Read the new Nature Communications publication that looks at WGD in the massive grass family: #wholegenomeduplication 🧪 community.alliancegenome.org/t/go-and-who...

Ever try to look up a term in AmiGO, but the results included extra terms? That's a feature not a 🐞! Read about how we use closures to show you ontology search results- and how you can restrict this if needed 🧪 community.alliancegenome.org/t/tuesdaytip...

New GO release! 2024-04-18 is available now! current.geneontology.org release.geneontology.org/2024-04-18 10.5281/zenodo.10999780 🧪 42,271 GO terms 7,668,043 annotations 1,536,109 gene products 5,404 species More info & release notes: community.alliancegenome.org/t/april-2024...

It's now more crucial than ever to cite resources you wish to keep using- GO, @alliancegenome.bsky.social, etc. In addition to citing these references, GO asks users/tool devs/etc. to include the GO Release. Does GO really change that much?... Yes! 🧪 community.alliancegenome.org/t/archive-of...

Today's paper highlight: new Scientific Reports publication that uses #GeneOntology and could help advance research on liver cancer #CancerResearch 🧪 community.alliancegenome.org/t/go-and-hep...

#TuesdayTips: Did you know there's a free #OpenAccess GO Handbook? We're highlighting the first chapter, which is an overview of #ontologies in general: 🧪 community.alliancegenome.org/t/go-handboo...

Sugar: eating it is easy... studying the ~9Gb sugarcane genome, not so easy. Read how Bao et al. assembled the ultra-complex modern hybrid sugarcane genome, and how GO helped identify important genes community.alliancegenome.org/t/go-and-hyb... 🧪🌾