🔥It's #MetalFriday and I have a new entry in my AOTY list! 🇫🇷 Blut Aus Nord - Ethereal Horizons 🎶Avant-garde Black Metal A clear departure from previous opuses, more melodic and atmospheric, most definitely ethereal #MetalHeads ##MetalSky

🎤 Dr Wenjia Bai (@imperialcollegeldn.bsky.social) 🫀 Look into your heart: From image to mesh 🎤 Dr Matthew Blackledge (@icr.ac.uk) 📷 Combining Bayesian Methods and AI for Improved Heterogeneous Imaging Biomarker Estimation in Whole-Body MRI of Advanced #ProstateCancer

💜Nov is #PancreaticCancerAwarenessMonth. #PancreaticCancer remains hard to detect & treat, with slow improvements in survival.🙏Thank you to those who supported this video, highlighting that progress relies on multistakeholder action to accelerate the adoption of early-detection tests. bit.ly/4rGiln1

🔥I haven't done that in a long while and missed #MetalFriday, but here is my current top 5 metal albums of 2025 as 🎄is upon us. #1 🇺🇸 Deafheaven - Lonely People With Power 🎶 Backgaze #MetalHeads #MetalSky

A study led by our Scientific Director Prof Axel Behrens, found that blocking protein SPP1 can boost survival & stop the spread of #PancreaticCancer in mice. A breakthrough that could pave the way for new targeted treatments. 👉 bit.ly/4gTvG6q @icr.ac.uk @imperialsandc.bsky.social @nature.com

How does one go about electing a new Prince of Darkness? Or does what the Darkness giveth the Darkness taketh away and leaderless Metal will stay?

🚨 New cross-institutional study from researchers at @imperialcollegeldn.bsky.social, @icr.ac.uk & @cruk-mi.bsky.social use microfluidic “vessel-on-chip” technology to reveal how circulating tumour cells release “shearosomes” and promote metastasis. 👉 bit.ly/3Ib6paq #Cancer #ConvergenceScience

Published today @natmed.nature.com www.nature.com/articles/s41... Thank you to all patients, families and research staff. @icr.ac.uk @icrdduiit.bsky.social‬ ‪@icr-ctsu.bsky.social @royalmarsden.org @ecmc-uk.bsky.social‬ @nihr.bsky.social @crukconvergence.bsky.social @cancerresearchuk.org ‪

Now online! Microtubules in Asgard archaea

Metabolic engineering to facilitate anti-tumor immunity www.cell.com/cancer-cell/...

👀 Intrinsic electrical activity drives small-cell lung cancer progression www.nature.com/articles/s41...

Protein codes promote selective subcellular compartmentalization | Science www.science.org/doi/10.1126/...

Engineered commensals for targeted nose-to-brain drug delivery: Cell www.cell.com/cell/fulltex...

📰High-resolution spatially resolved proteomics of complex tissues based on microfluidics and transfer learning www.cell.com/cell/fulltex...

Immune evasion through mitochondrial transfer in the tumour microenvironmenthttps:// www.nature.com/articles/s41586-024-08439-0

Rapid and scalable personalized ASO screening in patient-derived organoids www.nature.com/articles/s41...

Congratulations to Jenna Whalen on her Nature Cancer paper out today-a distinct take on nicks and their toxicity! rdcu.be/d60Td

🧠 How can we safely target structures deep inside the brain linked to disease? Imperial researchers hope to find out, thanks to ARIA funding! The project will develop minimally invasive brain stimulation methods to target regions and influence their activity 🔽 www.imperial.ac.uk/news/260073/...

Deciphering functional tumor-immune crosstalk through highly multiplexed imaging and deep visual proteomics www.cell.com/molecular-ce...

Therapeutic ultrasound is a prime example of convergence science - using the physics behind high frequency waves and applying it to biological systems to better diagnose, monitor and even target specific tumour sites. We support research that harnesses the power of ultrasound technologies. 1/3

🔥It's #MetalFriday! Time for my #AOTY 2024! Great millesime for \m/ music Starting at: *10 🇫🇷 #Alcest - Les Chants De L'Aurore (Blackgaze) *9 🇵🇹 #Gaerea - Coma (Black Metal) *8 🇮🇸 #ÁrstíðirLífsins - Aldrlok (Black/Folk Metal) *7 🇫🇮 #Wintersun - Time II (Ext. Power Metal) #MetalHeads #MetalSky

📰Transplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cells www.cell.com/cell/abstrac...

☕This year, in our #CellDeath focus: Toshitaka Nakamura & Marcus Conrad reviewed the susceptibility of #tumors to #ferroptosis, which could be exploited to treat #cancer. 👉https://rdcu.be/d493Q www.nature.com/articles/s41...

Finally, I'm in possession of one of the greatest albums ever made... in giant format! 🇺🇸 #Agalloch - The Mantle (2002) ##MetalHeads #MetalSky

🔥It's #MetalFriday! Next week, I'll be dropping my top 20 LPs of 2024. This week, my top 10 EPs! Starting at: *10: 🇺🇸 #Meanstreak - Blood Moon *9: 🇬🇧 #ColdInBerlin - The Body Is The Wound *8: 🇺🇸 #NokturnalFrost - Cold Grim Dead *7: 🇺🇸 #Enforced - A Leap Into The Dark #MetalHeads #MetalSky 👇*6 to *3

#EveryCellIsAnImmuneCell!💥Thrilled for the final version of our paper @cp-cell.bsky.social! We show that type III #interferons control ZBP1 activation driving gasdermin C cleavage & delaying gut repair by inducing #pyroptosis in intestinal epithelial cells! 1/n www.cell.com/cell/abstrac...

📰Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes www.cell.com/cell/fulltex...

Our work on cellular RNA interactions with MAVS that promote antiviral signaling is finally live. So grateful to our indispensable collaborators as well as reviewers who helped to strengthen our work. #RNA #innateimmunity #virology @ramlabuw.bsky.social www.science.org/doi/10.1126/...

🔥It's #MetalFriday! Here are recent highlights: 💀Best album: 🇩🇪 #Grundeis - Every Second An Ocean 🤘Hon. mentions: 🇦🇺 #Mesarthim - Anthropic Bias / Departure 🇦🇺 #AtraVetosus - Undying Splendour Only 1 \m/ Friday left! I'll drop my top EP 2024 before my top LP after new year. #MetalHeads #MetalSky

Our publication "A woman walking" following the reviewers' suggestions

🧪1/ 🚨New paper on ecDNAs from our lab! We reveal a strategy to engineer extrachromosomal DNA (ecDNA) amplifications in cells & mice. Let's dive in! Let’s dive in! 🧵👇 www.nature.com/articles/s41...

📰Early downmodulation of tumor glycolysis predicts response to fasting-mimicking diet in triple-negative breast cancer patients www.cell.com/cell-metabol...

"At the Heart of Winter" is my kind of Christmas album #Immortal #MetalSky

🔥It's #MetalFriday! I'll delay this week highlights to next week, so here are good albums I missed in previous months: 💀Best album: 🇫🇷 #Septaria - A* 🤘Hon. mentions: 🇷🇴 #PaenilEra - Idle Cage 🇺🇸 #Anarchÿ - The Spectrum Of Human Emotion 🇬🇷 #TheUsurper - Hell Breaks Loose #MetalHeads #MetalSky

👋We're looking for a #Software #Engineer to join our Centre, to develop and maintain a patient app platform as part of a collaborative project. Check out the job listing for more information jobs.icr.ac.uk/vacancies/10... @icrlondon.bsky.social

📢APPLY NOW for our Data Science #PhD training programme! We're providing 4 year PhD studentships with StatML to train the future academic leaders in #CancerResearch and statistical #MachineLearning. Deadline is 8th Jan. 🖱️ bit.ly/4fb0mNU @imperialcollegeldn.bsky.social @icrlondon.bsky.social

New peptide-driven proton sponge nano-assembly invented by the Jokerst lab @ucsd induces cancer cell death via the lysosome rupturing-regulated pyroptosis and necroptosis. Thanks for including us in this amazing study!

📰How NINJ1 mediates plasma membrane rupture and why NINJ2 cannot www.cell.com/cell/abstrac...

📰Discovery and engineering of the antibody response to a prominent skin commensal www.nature.com/articles/s41...

📰Sacrificial capillary pumps to engineer multiscalar biological forms www.nature.com/articles/s41...

Want a #PhD that uses #ChemicalBiology to address unmet needs in #CancerResearch? 📢APPLY NOW for our non-clinical PhD training programme with The Institute of Chemical Biology #ICB and learn from world leading experts from @imperialcollegeldn.bsky.social and @icrlondon.bsky.social bit.ly/3BpAz6U

📰Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells #CellCompetion #CanSky www.nature.com/articles/s41...

📰Simple and effective embedding model for single-cell biology built from ChatGPT www.nature.com/articles/s41...

I am so excited to share the biggest (and best) part of my #PhD in @maxreichertmd.bsky.social lab We show how inter/intra-tumoral #heterogeneity impacts plasticity and treatment resistance by using #PDAC #organoids @natureportfolio.bsky.social www.nature.com/articles/s41...

📰A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control www.cell.com/immunity/abs...

📰A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor #CanSky #OncoSky www.cell.com/cell/fulltex...

This deserves an update to keep up with the youth #celldeath #pyroptosis #apoptosis #CanSky

Still missing Dimebag very much... 20 years without any like him! #MetalSky youtu.be/aDACorIaxNw?...

📰Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing www.cell.com/cell/fulltex...

🔥It's #MetalFriday! As I go through this week's releases, last week's highlights: 💀Best album: 🇮🇹 #Bedsore - Dreaming The Strife For Love 🤘Hon. mentions: 🇬🇧 #HiddenMothers - Erosion / Avulsion 🇺🇸 #Painkiller - Samsara 🇪🇸 #VidresALaSang - Virtut Del Desencís + 🇳🇴Ulver 🇬🇷Dizziness #MetalHeads #MetalSky