Centre of Molecular Structure never sleeps - even during the quietest week of summer. With Jan Blaha, they collected high-quality X-ray diffraction data on our D8 Venture, aiming to resolve a protein structure at ~1.8 A. Looking forward to collecting data with you!

The symposium was chaired by @dmsabatini.bsky.social of IOCB Boston, whose work has significantly contributed to the understanding of the #mTOR signaling pathway, and Kateřina Rohlenová of @ibtcas.bsky.social, who investigates the metabolic relationships between cancer cells and healthy cells.

🧬 Cancer cells and immune cells may compete for mitochondria. A new Trends in Cancer article looks at horizontal mitochondrial transfer and its possible role in tumor progression, antitumor immunity and future therapies. Read more: www.sciencedirect.com/science/arti...

A new study in @natcomms.nature.com shows that mechanical properties of breast carcinoma tissue can be linked to priming anti-cancer immune responses. Research by Giorgio Scita (University of Milan), @ibtcas.bsky.social, et al. Study ➡️ www.nature.com/articles/s41...

Our colleagues Gabriela Pavlínková, Valerie Fabríciová, Romana Bohuslavová and Věra Slaninová attended the European Islet Study Group Conference 2026 in Barcelona. Our team presented two posters and joined discussions with the international islet research community.

10 years of BIOCEV. 🔬 A decade of collaboration across institutions, disciplines and people and an important part of Czech biomedical research with international reach. We are glad to be part of this project.

Towards Instruct Biennial conference in Brussels by example. @instruct-eric.bsky.social covers travel costs to the experiments up to 500€, up to 550€ when not flying. Pro tip: many European locations are accessible by night trains from Linz. See you in Brussels!

Droplet Digital PCR World on Tour 2026 has started at BIOCEV 🧬 Hosted by GeneCore in collaboration with Bio-Rad, the workshop combines ddPCR talks with hands-on work on the QX700 instrument in the GeneCore lab. Practical training continues tomorrow.

We hosted two student groups in our labs this April 🧬 One visited through Hejbni vědou!, organised by Asociace genové terapie, and the other came from Sunny Canadian School. A closer look at how research works in practice.

𝐒𝐭𝐫𝐮𝐜𝐭𝐮𝐫𝐚𝐥 𝐛𝐢𝐨𝐥𝐨𝐠𝐲 𝐢𝐧 𝐚𝐜𝐭𝐢𝐨𝐧 𝐚𝐭 𝐭𝐡𝐞 𝐂𝐂𝐏𝟒 𝐖𝐨𝐫𝐤𝐬𝐡𝐨𝐩 𝟐𝟎𝟐𝟔 𝐢𝐧 𝐍𝐨𝐯é 𝐇𝐫𝐚𝐝𝐲 🧬 ~30 students from across Europe and 20 tutors coming together to learn and share knowledge in crystallography and cryo-EM. Our colleagues Petr Kolenko and Jan Dohnálek contributed with lectures. @structbiocssb.bsky.social

🔬 Hands-on workshop alert! Learn nanoDSF, DLS & Spectral Shift methods - and try them on your own samples at the NanoTemper Technologies in CMS workshop. 📅 May 5–6, 2026 📍 BIOCEV, Vestec 👉 More info: 1url.cz/2eEKO

📢 Free webinar on MOSBRI project results Discover the eSPC software suite and the Molecular Biophysics Database (MBDB) - tools designed to support and streamline your research. 📅 April 8 | 13:00 CEST 👉 cassyni.com/events/WDEKq...

🧬 Next Cytoskeletal Brew is coming up! This time with Giampietro Schiavo talking about axonal transport and neurodegeneration. 📅 April 28 | 5:00 PM 📍 CAS building, Národní 3 A nice chance to connect with the local cytoskeleton community! 👉 sites.google.com/natur.cuni.c...

Great to see the structural biology community come together in Nové Hrady for the #XXIIDiscussions and CIISB User Meeting 🧬 👏 Congrats to all student awardees - especially our colleague Jiří Srogoň for the @structbiocssb.bsky.social poster prize!

📢You’re invited to a WiSe@IBT guest lecture at BIOCEV: 𝐌𝐚𝐫𝐜𝐢 𝐋𝐨𝐛𝐞𝐥, 𝐏𝐡𝐃 𝐓𝐡𝐞 𝐄𝐯𝐨𝐥𝐮𝐭𝐢𝐨𝐧 𝐨𝐟 𝐏𝐫𝐞𝐧𝐚𝐭𝐚𝐥 𝐒𝐭𝐫𝐞𝐬𝐬 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡: 𝐓𝐡𝐫𝐞𝐞 𝐃𝐞𝐜𝐚𝐝𝐞𝐬 𝐨𝐟 𝐃𝐢𝐬𝐜𝐨𝐯𝐞𝐫𝐢𝐞𝐬 📅 21 April 2026 | 10:00 a.m. 📍 BIOCEV Auditorium Don't miss out on this unique opportunity! 👉Register: 1url.cz/5eweM

Tau protein modifications emerging in early stages of Alzheimer’s disease disrupt cellular cytoskeleton protection and enable its degradation. ➡️ www.ibt.cas.cz/en/news/Tau-... @ibtcas.bsky.social @sciencecharles.bsky.social @cnrs.fr @iphys-cas.bsky.social

BIOCEV SEMINAR SERIES 📆 19. 3. 2026 🕒 3 p.m. 📍BIOCEV, Vestec

Two days with the EOSC NRP project team in the Vysočina region 🤝 A chance to step back from day-to-day tasks, share updates across teams, discuss open questions, and look at where the project is heading next. Great discussions and many useful exchanges across activities. #OpenScience #ResearchData

🧬 Our colleague Gabriela Pavlínková is serving as Guest Editor for the Scientific Reports collection “Advances in Embryonic Development.” Proud to see her shaping this exciting research area.

Join us for the next seminars from the BIOCEV Seminars Series! 📆 5. 3. 2026 🕒 3 p.m. 📍BIOCEV, Vestec

📢 𝐍𝐮𝐜𝐥𝐞𝐢𝐜 𝐀𝐜𝐢𝐝 𝐒𝐭𝐫𝐮𝐜𝐭𝐮𝐫𝐞 𝐀𝐧𝐧𝐨𝐭𝐚𝐭𝐢𝐨𝐧 & 𝐏𝐫𝐞𝐝𝐢𝐜𝐭𝐢𝐨𝐧 𝐇𝐚𝐜𝐤𝐚𝐭𝐡𝐨𝐧 𝟐𝟎𝟐𝟔 Over three days, participants will work on interoperable workflows, data standards, and benchmarking approaches with an emphasis on reproducibility and community reuse. Learn more 👉 1url.cz/ZeugF Register here 👉 1url.cz/neugR

🎉 Congratulations to Jana Campbell on receiving the 2025 PhD Thesis Award from the Czech Society for Structural Biology. Kudos also to her supervisor Cyril Barinka. 👏 👉 More: 1url.cz/Zezie

📢 We are hiring! • Postdoctoral Researcher in Molecular Transport Dynamics • PhD Positions in Quantitative Imaging of Ciliary Transport – Track A: Single-Molecule Imaging – Track B: Imaging Technology & Method Development 📍 BIOCEV, near Prague 👉 Details via QR codes

Little visitors, big curiosity 💛 Children from Vestec Kindergarten explored the laboratories of the Centre of Molecular Structure and discovered that science can be fun from a very young age. 🧪👀 Thank you for the visit! ✨

Carta Genum, founded by Lukáš Valihrach and Daniel Žucha, raised pre-seed funding from Czech Founders VC and joined the Sherpa accelerator. 🧬 They aim to make biological data analysis accessible — without black-box AI or coding barriers. 👉https://1url.cz/gJy66

✨ 𝐆𝐚𝐭𝐞𝐬 𝐨𝐟 𝐈𝐦𝐚𝐠𝐢𝐧𝐚𝐭𝐢𝐨𝐧 ✨ Mouse cerebellum captured through the lens of science and art. 🏆 December Picture of the Month 📸 Lenka Gmiterková

A new paper🧬Bacteria sense the antibiotic rifampicin through a widespread dual-promoter based alarm system Nucleic Acids Research (2026) Lab of Microbial Genetics and Gene Expression IMIC, @iocbprague.bsky.social @ibtcas.bsky.social @akademievedcr.bsky.social ➡️ academic.oup.com/nar/article/...

🧬 New Nucleic Acids Research paper: updated standards for validating RNA/DNA covalent geometry in PDB models. Introducing a 3-tier scheme: 🟢Preferred 🟡Allowed 🔴Of Concern — to reduce false alarms & improve future deposits. 🚀 doi.org/10.1093/nar/...

𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐧𝐞𝐰 𝐍𝐮𝐜𝐥𝐞𝐢𝐜 𝐀𝐜𝐢𝐝𝐬 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐩𝐚𝐩𝐞𝐫 🧬 DNATCO v5.0 is a browser-based platform for 3D nucleic acid structure annotation + validation - fast, interactive, privacy-friendly. 📄 doi.org/10.1093/nar/... 🌐 dnatco.datmos.org

Congratulations to Prof. Mikael Kubista, recognized as a 2025 ScholarGPS Highly Ranked Scholar™ (Lifetime) — placing him in the top 0.05% of scholars worldwide. #30 in PCR and #41 in Gene expression profiling.

Happy New Year 2026 from IBT CAS ✨ Thanks to everyone we collaborate with — wishing you health, inspiration and exciting discoveries in 2026 🔬🤝

📣We’re proud to announce the successful completion of our first Single-Cell RNA-seq course at the Institute of Molecular Genetics 📅 1–3 December 2025 🤝 In collaboration with ELIXIR CZ, @ibtcas.bsky.social and MetaCentrum

𝐆𝐫𝐞𝐚𝐭 𝐭𝐨 𝐬𝐞𝐞 𝐭𝐡𝐞 𝐉𝐮𝐧𝐢𝐨𝐫 𝐅𝐚𝐜𝐮𝐥𝐭𝐲 𝐢𝐧𝐢𝐭𝐢𝐚𝐭𝐢𝐯𝐞 𝐚𝐭 𝐂𝐡𝐚𝐫𝐥𝐞𝐬 𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲 𝐟𝐞𝐚𝐭𝐮𝐫𝐞𝐝 𝐢𝐧 𝐍𝐚𝐭𝐮𝐫𝐞 👉 1url.cz/eJc6z Proud that our colleague @katerinarohlena.bsky.social contributed to early discussions and ideas around the #PIForum, which helped inspire initiatives that are now gaining international attention. 🚀

🔬 Our new study shows that mitochondrial respiration is essential for early tumour growth. Cancer cells can import mitochondria from nearby cells to restore pyrimidine synthesis and proliferate. A key vulnerability: DHODH — its loss fully blocks tumour growth. 📄 Cancer Research | 1url.cz/wJOxT

Naše kolegyně Aditi Chatterjee získala Pamětní grant Martiny Roeselové 2026! 🎉 Velká gratulace a díky @nf-iocbtech.bsky.social za podporu mladých vědců-rodičů. ❤️

🔬 𝐗𝐗𝐕𝐈𝐈𝐈. 𝐁𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐃𝐚𝐲𝐬 opened with excellent talks and lively discussions. Congratulations to Prof. Jaroslav Petr on the Babák Medal. 👉 Join us again tomorrow. 1url.cz/gJOWh

Kateřina Rohlenová @katerinarohlena.bsky.social z @ibtcas.bsky.social je uznávanou vědkyní v oblasti nádorové biologie. V roce 2023 získala podporu grantu MIT-Czech Republic IOCB Tech Foundation Seed Fund, díky němuž navázala spolupráci s MIT a nyní dokončuje přelomový článek o nádorových buňkách. ⤵️

🧬 The 4th Prague Symposium on Cancer Metabolism brought together experts to discuss new insights in tumor metabolism. We’re proud that two of our PhD students — 🏆 Pavel Jakoubě and 🏆 Mariia Hrysiuk — received a Best Poster Prize (2 of only 3 awarded). 👏 Congratulations!

🧫 Rychlá regenerace jater pod lupou vědců Více ⬇️ www.avcr.cz/cs/pro-media/tiskove-zpravy/Jatra-pri-regeneraci-pretvareji-toxicky-amoniak-na-latku-podporujici-rust/

💚 𝐓𝐰𝐨 𝐝𝐚𝐲𝐬 𝐟𝐮𝐥𝐥 𝐨𝐟 𝐜𝐮𝐫𝐢𝐨𝐬𝐢𝐭𝐲, 𝐬𝐜𝐢𝐞𝐧𝐜𝐞 𝐚𝐧𝐝 𝐠𝐫𝐞𝐚𝐭 𝐞𝐧𝐞𝐫𝐠𝐲! Almost 200 students explored our labs 🔬 Maybe some of them will be future scientists — or Nobel Prize winners. 😉

🏆 𝗧𝘄𝗼 𝗼𝗳 𝗼𝘂𝗿 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁𝘀 𝗵𝗮𝘃𝗲 𝗯𝗲𝗲𝗻 𝗮𝘄𝗮𝗿𝗱𝗲𝗱 𝗯𝘆 𝘁𝗵𝗲 @akademievedcr.bsky.social 🔬 Prof. Jiří Neužil – 𝗣𝗿𝗮𝗲𝗺𝗶𝘂𝗺 𝗔𝗰𝗮𝗱𝗲𝗺𝗶𝗮𝗲 𝟮𝟬𝟮𝟱 🧫 Dr. Aniruddha Mitra – 𝗟𝘂𝗺𝗶𝗻𝗮 𝗤𝘂𝗮𝗲𝗿𝘂𝗻𝘁𝘂𝗿 𝟮𝟬𝟮𝟱 💚 Congratulations on this exceptional success and recognition of their work! Read more 👉https://1url.cz/NJIjr

RNA is still waiting for its “AlphaFold moment.” 🔬✨ At IBT CAS we’re tackling this challenge head-on. Read more 👉 1url.cz/YJhsw

Don’t miss the opportunity!

🆕𝐍𝐞𝐰 𝐫𝐞𝐯𝐢𝐞𝐰 𝐟𝐫𝐨𝐦 𝐨𝐮𝐫 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐨𝐟 𝐋𝐢𝐠𝐚𝐧𝐝 𝐄𝐧𝐠𝐢𝐧𝐞𝐞𝐫𝐢𝐧𝐠! Colleagues explored key drivers of metastatic non-small cell lung cancer (mNSCLC): 🔹 tumor heterogeneity 🔹 oncogenic drivers & resistance 🔹 immunosuppressive TME 📖 biosignaling.biomedcentral.com/articles/10....

🚨 New paper out! We built fiSPR, a platform combining SPR biosensing + light 💡 to study light-responsive proteins. 🔹 Blue light → EL222 dimerization + DNA binding 🔹 UV light → interleukin–receptor interactions 📖 doi.org/10.1016/j.bi...

🎉Congratulations to our colleague Daniel Žucha on receiving the 𝙔𝙤𝙪𝙣𝙜 𝙉𝙚𝙪𝙧𝙤𝙨𝙘𝙞𝙚𝙣𝙩𝙞𝙨𝙩𝙨 𝘼𝙬𝙖𝙧𝙙 𝙛𝙤𝙧 𝙊𝙪𝙩𝙨𝙩𝙖𝙣𝙙𝙞𝙣𝙜 𝙒𝙤𝙧𝙠 (𝟮𝟬𝟮𝟯–𝟮𝟬𝟮𝟰) 🧠✨ The prize was awarded by the Czech Neuroscience Society at the biannual #CNS2025 meeting for his work published in PNAS 👉pnas.org/doi/10.1073/pn… 👏

At @eisg2025 in Malmö 🇸🇪: 🎤Valeria Fabríciová gave a talk on sex differences in ISL1-deficient diabetic mouse model 📸Věra Slaninová presented her poster on ISL1 and epigenetic regulation in pancreatic endocrine development Great discussions, and inspiration for future research. Proud of our team! 💡

𝙋𝙤𝙡𝙞𝙨𝙝 🇵🇱 𝙖𝙣𝙙 𝘾𝙯𝙚𝙘𝙝 🇨🇿 𝙍𝙚𝙨𝙚𝙖𝙧𝙘𝙝 𝙏𝙚𝙖𝙢𝙨 𝙈𝙚𝙚𝙩 𝙞𝙣 𝙋𝙤𝙯𝙣𝙖𝙣 📅From Aug 25–29, IBT CAS (Prof. Bohdan Schneider) met with IBCH PAS (Prof. Marta Szachniuk) in Poznań. 🔬 Joint project: AI & graph-based tools for RNA 3D models 🌍 Goal: open-access solutions for computational structural biology.

🧠Don’t miss two outstanding neuroscience lectures! 📅Sept 5, 2025 13:00 Prof. Marcela Pekna – “𝙄𝙢𝙥𝙧𝙤𝙫𝙞𝙣𝙜 𝙨𝙩𝙧𝙤𝙠𝙚 𝙧𝙚𝙘𝙤𝙫𝙚𝙧𝙮 – 𝙛𝙧𝙤𝙢 𝙩𝙧𝙖𝙣𝙨𝙘𝙧𝙞𝙥𝙩𝙤𝙢𝙞𝙘𝙨 𝙩𝙤 𝙣𝙚𝙬 𝙩𝙧𝙚𝙖𝙩𝙢𝙚𝙣𝙩 𝙨𝙩𝙧𝙖𝙩𝙚𝙜𝙞𝙚𝙨” 14:00 Prof. Milos Pekny – “𝘼𝙨𝙩𝙧𝙤𝙘𝙮𝙩𝙚𝙨 𝙖𝙨 𝙢𝙖𝙟𝙤𝙧 𝙥𝙡𝙖𝙮𝙚𝙧𝙨 𝙞𝙣 𝘾𝙉𝙎 𝙙𝙞𝙨𝙚𝙖𝙨𝙚𝙨” 📍 IBT, BIOCEV campus, Vestec

🚀Věda, která mění životy! Naše kolegyně Kateřina Komrsková patří mezi světovou špičku v oblasti reprodukční biologie. 🔬✨ V rozhovoru mluví nejen o mužské neplodnosti, ale i o objevech, které mohou pomoci zachránit ohrožené druhy. 🌍💚 👉https://1url.cz/dJVGl