New paper out: Care preferences of older migrants and minority ethnic groups with various care needs: A scoping review.: Peters-Nehrenheim, Viktoria; Rommerskirch-Manietta, Mike; Tezcan-Güntekin, Hürrem; et al. PLOS ONE Vol. 21, no. 1, p. e0341147 - | Thanks for sharing #dzne #papers

New paper out: Alpha-synuclein quantitative seed amplification assay predicts conversion to dementia.: Bräuer, Stefan; Sondermann, Verena; Schniewind, Inaki; et al. Alzheimer's and dementia Vol. 22, no. 1, p. e71167 | Thanks for sharing #dzne #papers

New paper out: From cigarettes to symptoms: the association between smoking and depression in the German National Cohort (NAKO).: Völker, Maja P; Callies, Carolin M; Frank, Josef; et al. BMC public health Vol. 26, no. 1, p. 301 | Thanks for sharing #dzne #papers

DZNE Munich: Change of Leadership. Mikael Simons New Site Speaker. 👉 www.dzne.de/en/im-fokus/...

New paper out: Intranasal blood-brain barrier bypass enables sequential mitochondria-targeted bioengineered nanolamellar system for ischemic stroke therapy.: Yin, Yue; Li, Zixuan; Shu, Weijie; et al. Nature Communications Vol. 17, no. 1, p. 760 | Thanks for sharing #dzne #papers

New paper out: Secondary obsessive-compulsive syndromes: a systematic literature review resulting in 228 suspected cases.: Runge, Kimon; Feige, Bernd; Schiele, Miriam A; et al. Molecular psychiatry Vol. 31, no. 2, p. 1121 - 1131 | Thanks for sharing #dzne #papers

📢 Our latest work is now in press at @natcomms.nature.com! A great collaboration with the Schultze lab @dzne.science & Denali Therapeutics, to identify molecular and functional changes associated with TREM2 signalling in microglia, with implications for TREM2 agonism.. www.nature.com/articles/s41...

New paper out: Brain volume trajectories in Down syndrome and autosomal dominant Alzheimer's disease.: Kennedy, James T; Wisch, Julie K; Boerwinkle, Anna H; et al. Alzheimer's and dementia Vol. 22, no. 1, p. e71103 | Thanks for sharing #dzne #papers

New paper out: Integrin-dependence of extramedullary erythropoiesis in the spleen of Jak2-V617F positive myeloproliferative neoplasm in mice.: Baldauf, Conny K; Poschmann, Linda; Edelmann-Stephan, Bärbel; et al. Experimental hematology Vol. 154, p. 105340 - | Thanks for sharing #dzne #papers

New paper out: [18F]FDG-PET/CT Imaging for Response Characterisation of Experimental Melanomas to Anti-PD-L1/Anti-CTLA-4 Immunotherapy.: Antons, Melissa J; Kloiber-Langhorst, Sandra; Hirner-Eppeneder, Heidrun; et al. Molecular imaging & biology Vol. 27, no. 6, p.… | Thanks for sharing #dzne #papers

New paper out: Association between polygenic risk for Major Depression and brain structure in a mega-analysis of 50,975 participants across 11 studies.: Shen, Xueyi; Toenders, Yara J; Han, Laura K M; et al. Molecular psychiatry Vol. 31, no. 2, p. 611 - 621 | Thanks for sharing #dzne #papers

New paper out: Genetisch informierte Therapie in der Psychiatrie: neue Dynamik durch APOE und Antikörpertherapie der Alzheimer-Krankheit | Genetically informed treatment in psychiatry: new dynamics through APOE and antibody treatment of Alzheimer's disease:… | Thanks for sharing #dzne #papers

New paper out: Clinical and Genotypic Spectrum of Twinkle-Related Disorders: Insights From a Multinational Cohort Study.: Lopriore, Piervito; Ünlütürk, Zeynep; Klopstock, Thomas; et al. Neurology Vol. 106, no. 3, p. e214401 | Thanks for sharing #dzne #papers

New paper out: Multivariate associations of motor performance, sleep quality, depressive symptoms, and grey matter volume in younger and mid-to-older adults.: Küppers, Vincent; Bi, Hanwen; Nicolaisen-Sobesky, Eliana; et al. Scientific reports Vol. 16, no. 1, p.… | Thanks for sharing #dzne #papers

New paper out: High‐Throughput 3D Glioblastoma Model in Glycosaminoglycan Hydrogels for Personalized Therapeutic Screening: Trautmann, Rajvinder Kaur; Dennison, Nicholas; McCortney, Kathleen; et al. Macromolecular bioscience Vol. 26, no. 1, p. e00394 | Thanks for sharing #dzne #papers

New paper out: Abnormal Amplitude-Integrated Electroencephalography and Acidosis as Key Criteria Initiating Therapeutic Hypothermia in Asphyxiated Newborns - Data From the German Hypothermia Registry.: Demir, Sebiha; Groteklaes, Anne; Dresbach, Till; et al. Acta… | Thanks for sharing #dzne #papers

New paper out: Immunotherapies in progressive multiple sclerosis.: Neziraj, Tradite; Kappos, Ludwig; Pröbstel, Anne-Katrin   | Thanks for sharing #dzne #papers

New paper out: Elenbecestat and Compound 89 Potently Inhibit BACE1 but Not BACE2 When Subchronically Dosed in Non-Human Primates.: Tschirner, Sarah K; Schmidt, Andree; Ito, Mana; et al. Proteomics Vol. 26, no. 1, p. 100 - 107 | Thanks for sharing #dzne #papers

New paper out: In-Source Fragmentation Annotation in Sterol Mass Spectrometry Imaging.: Sidorov, Iulia; Ogrinc, Nina; Spieth, Lena; et al. Analytical chemistry Vol. 98, no. 1, p. 509 - 518 | Thanks for sharing #dzne #papers

New paper out: Bildgebung neurologischer Nebenwirkungen unter Immuntherapien : Immuncheckpoint-Inhibitoren und CAR-T-Zellen | Imaging of neurological adverse events associated with immunotherapies : Immune checkpoint inhibitors and CAR-T cells: Neumann, Timotheus… | Thanks for sharing #dzne #papers

A DZNE-led project in Germany is testing an app for people with dementia living at home. It also supports family caregivers. The app connects users with memory-clinic professionals and practical resources. Goal is to reduce caregiver burden and stabilize home care. 👉 www.dzne.de/en/news/pres...

Proud to share that PD Dr. Patrick Öckl has been awarded the Hirnliga Research Prize 2025 for pioneering work on a blood biomarker to detect Alzheimer’s-related changes early. His research on beta-synuclein offers promising insights for minimally invasive diagnosis. 👉 www.dzne.de/en/im-fokus/...

New paper out: Whole-brain meso-vein imaging in living humans using fast 7-T MRI.: Gulban, Omer Faruk; Stirnberg, Rüdiger; Tse, Desmond Ho Yan; et al. Science advances Vol. 12, no. 2, p. eaea4540 | Thanks for sharing #dzne #papers

New paper out: International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative.: Dodich, Alessandra; Panzavolta, Andrea; Funghi, Giulia; et al. Alzheimer's… | Thanks for sharing #dzne #papers

New paper out: Fat Amount Rather Than Fatty Acid Composition Influences Postprandial Hunger, Satiety and Attention in Men and Women with a Risk Phenotype for Cardiometabolic Diseases: A Randomized Crossover Trial.: Diekmann, Christina; Schiemann, Tim B; Kienēs,… | Thanks for sharing #dzne #papers

New paper out: Review: Kutzleben, Milena Ageing and society Vol. 38, no. 1, p. 214 - 216 | Thanks for sharing #dzne #papers

New paper out: Key components of person‐centered care for people with dementia: A systematic review of interventions to design a patient preference study: Raedke, Anika; Afi, Adel; Edvardsson, David; et al. Alzheimer's and dementia Vol. 17, no. S7, p. e052134 | Thanks for sharing #dzne #papers

New paper out: Models in Inflammation and Immunopharmacology: Secchim Ribeiro, Lucas   | Thanks for sharing #dzne #papers

🧠🦠 New preprint out! Systemic inflammation fundamentally reshapes amyloid plaques — shifting them toward non-compacted, filamentous Aβ states that strongly predict neuritic damage across mouse models and human Alzheimer’s disease. #Alzheimers #Neuroimmunology #Microglia #Amyloid #PET #Inflammation

New paper out: Developing a Novel Reference Region for PI‐2620‐PET Imaging to Facilitate Assessment of 4‐Repeat Tauopathies: Frontzkowski, Lukas; Gross, Mattes; Roemer-Cassiano, Sebastian; et al. Alzheimer's and dementia Vol. 21, no. S2, p. e104777 | Thanks for sharing #dzne #papers

New paper out: Polygenic risk for psychiatric disorders and its association with neuropsychiatric symptoms in dementia.: Najar, Jenna; de Rojas, Itziar; Dalmasso, Maria Carolina; et al. International review of psychiatry Vol. 37, no. 8, p. 816 - 826 | Thanks for sharing #dzne #papers

New paper out: Supplementation with short-chain fatty acids and a prebiotic improves clinical outcome in Parkinson's disease: a randomized double-blind prospective study.: Hegelmaier, Tobias; Duscha, Alexander; Desel, Christiane; et al. Scientific reports Vol. 16,… | Thanks for sharing #dzne #papers

New paper out: Dementia with lewy bodies and Alzheimer´s Disease overlap syndrome with PSP-like phenotype caused by co-pathologies - a case report.: Häfner, Friederike; Bernhardt, Alexander; Goldschagg, Nicolina; et al. Journal of neurology Vol. 273, no. 1, p. 62 | Thanks for sharing #dzne #papers

New paper out: Plasma p ‐tau 217 as a suitable biomarker for monitoring cognitive changes in Alzheimer's disease: Biel, Davina; Steward, Anna; Dewenter, Anna; et al. Alzheimer's and dementia Vol. 21, no. S2, p. e104771 | Thanks for sharing #dzne #papers

New paper out: Multi‐tracer PET monitoring of an immunomodulatory therapy in 4R tauopathy: Evaluating a novel drug's impact on glial function and protein pathology: Bathe, Tim; Salomasova, Svetlana; Lalia, Manvir; et al. Alzheimer's and dementia Vol. 21, no. S2,… | Thanks for sharing #dzne #papers

New paper out: Integrating simulated and experimental data to identify mitochondrial bioenergetic defects in Parkinson's Disease models.: Chenna, Sandeep; Joselin, Alvin; Theurey, Pierre; et al. PLOS ONE Vol. 21, no. 1, p. e0339326 - | Thanks for sharing #dzne #papers

New paper out: AI Superresolution: Converting T1‐weighted MRI from 3T to 7T resolution toward enhanced imaging biomarkers for Alzheimer's disease: Gicquel, Malo; Flood, Gabrielle; Zhao, Ruoyi; et al. Alzheimer's and dementia Vol. 21, no. S2, p. e106600 | Thanks for sharing #dzne #papers

New paper out: Nucleus Basalis of Meynert: Functional Connectivity and Morphometry in Alzheimer's Disease and Frontotemporal Dementia: Kindler, Christine; Gillis, Grace; Bhalerao, Gaurav V; et al. Alzheimer's and dementia Vol. 21, no. S2, p. e105620 | Thanks for sharing #dzne #papers

New paper out: Early changes in basal forebrain volume and cognitive function in preclinical autosomal dominant Alzheimer's disease: He, Bing; Ospina, Paula; Espinosa, Alejandro; et al. Alzheimer's and dementia Vol. 21, no. S2, p. e105027 | Thanks for sharing #dzne #papers

🔬 As part of the World Brain Health Forum 2026, the second session of the day explored emerging perspectives in neuroscience through the insights of early-career researchers. #WBHF2026

For its 15th anniversary, the Brain Institute is hosting the World Brain Health Forum in Paris on Jan 14–15, 2026. Experts worldwide will discuss brain health challenges and turning science into solutions. 👉 Registration is mandatory. Program & info: https://2026.worldbrainhealthforum.org/en/

DZNE is part of the European research initiative ACCESS-AD, receiving ~€1M to improve Alzheimer’s diagnosis and care. The project explores innovative tools like app-based cognitive tests to support earlier and better treatment. 👉 www.dzne.de/en/im-fokus/...

New paper out: Axon initial segment dynamics during associative fear learning: Benoit, Chloé Maëlle; Ganea, Dan Alin; Paricio-Montesinos, Ricardo; et al. Nature neuroscience  | Thanks for sharing #dzne #papers

New paper out: Changes in Task‐evoked Pupil Dilation during Emotional Memory as a Marker of Noradrenergic Function in Healthy Aging and MCI: Zhunussova, Alina; Loane, Clare; Kurt, Elif; et al. Alzheimer's and dementia Vol. 21, no. S7, p. e108410 | Thanks for sharing #dzne #papers

New paper out: Cognitive training–related volumetric changes in the A36 perirhinal area are associated with mnemonic discrimination gains in older adults: a 7T MRI study: Iliopoulos, Panagiotis; Gellersen, Helena M.; Rong, Boyan; et al. Alzheimer's and dementia… | Thanks for sharing #dzne #papers

New paper out: Anti‐oligomeric PRI‐002 does not cause ARIA‐E in an ongoing Phase 2 trial: Peters, Oliver; Jürgens, Dagmar; Tischler, Gerhard; et al. Alzheimer's and dementia Vol. 21, no. S7, p. e108724 | Thanks for sharing #dzne #papers

New paper out: Long‐Read Sequencing Reveals Ancestral intragenic APOE Haplotypes with Distinct Roles in Alzheimer’s Disease: Ruiz, Agustin; García-González, Pablo; Puerta, Raquel; et al. Alzheimer's and dementia Vol. 21, no. S7, p. e108005 | Thanks for sharing #dzne #papers

Happy to share that our #JOSS paper on MotilA is now published 😊 #OpenSource #Python pipeline for reproducible, batch-scale analysis of #microglia fine-process motility in 3D/4D in vivo multiphoton imaging: 📄 doi.org/10.21105/jos... 💻 github.com/FabrizioMusa... #Neuroscience 🧪 #OpenScience

New paper out: Risk of Epilepsy and Factors Associated With Time to Seizure Remission in Anti-LGI1 Encephalitis: Long-Term Outcome in 236 Patients.: Baumgartner, Tobias; Freyberg, Moritz; Campetella, Lucia; et al. Neurology: Neuroimmunology & Neuroinflammation ;… | Thanks for sharing #dzne #papers

New paper out: CSF Biomarkers of Neuroinflammation in Prediction of Brain Atrophy: Özlü, Serap; Grazia, Alice; Dyrba, Martin; et al. Alzheimer's and dementia Vol. 21, no. S7, p. e108159 | Thanks for sharing #dzne #papers