We present a site‑saturation functional screens of missense variants in the high-risk breast cancer susceptibility gene PALB2. Damaging missense variants confer a high risk of breast cancer! Thanks to all co-authors and to KWF for financially supporting our work! www.nature.com/articles/s41...

Verry happy and thankful that the Dutch Cancer Society (KWF)/Alpe d'Huzes has decided to fund our research. We aim to determine how disabling Fanconi anemia proteins can kill BRCA1-deficient cancer, paving the the way for a new personalized treatment for BRCA1-patients. www.kwf.nl/nieuws/toeke...

Great response so far for the DNA Repair Meeting in April 2026 ! 🧬 A few poster spots are still available. ✨ Early-bird registration extended to February 28th ✨ New invited speakers added: check the site: dnarepairmeeting-egmond2026.com Don’t miss this outstanding meeting!

Registration is open!🧬 Join us at Egmond aan Zee (April 19–24, 2026) for the next DNA Repair Meeting. We have an amazing line-up of speakers. 📅 Deadline for early registration: Jan 10, 2026 🔗 dnarepairmeeting-egmond2026.com

A must for all DNA repair aficionados! Egmond DNA Repair Meeting → April 19–24, 2026 🇳🇱 ✔️ Confirmed top speakers ✔️ Ample opportunities for talks & posters Don’t miss it: dnarepairmeeting-egmond2026.com

We present Repli-ID, an approach to identify proteins affecting DNA replication. Lge1 and Rox1 are new regulators of this process. Great work by @sophievdhorst.bsky.social, @lleonie.bsky.social and co-authors in collaboration with @andreichabes.bsky.social. tinyurl.com/mvvcp3xe

Mark your calendar: the next Egmond DNA repair meeting will take place in 2026 from April 19 - 24! You can pre-register to receive announcement here: forms.lumc.nl/lumc2/Egmond Registration will open by June 2025.

Deadline approaching for the EMBO workshop "Chromatin dynamics and nuclear organisation in genome maintenance", June 17-20, 2024, Leiden, the Netherlands. Speaker slots available! Register before April 1, 2024! meetings.embo.org/event/24-chr...

The EMBO workshop "Chromatin dynamics and nuclear organisation in genome maintenance" will take place from June 17-20, 2024, in Leiden, the Netherlands. Check our fantastic list of speakers and register before April 1, 2024, at meetings.embo.org/event/24-chr.... Speaker slots available!

We are searching for a highly-motivated postdoc to study a newly-identified DNA repair protein, ZNF384, using state of the art functional genomics and biochemistry approaches. Interested in joining vanattikumlab.org? Apply via the link below: tinyurl.com/hedwn8nx