Congratulations to Dr. Adam Marc, the latest minted PhD from Jefferson Neuroscience! He did lovely work in the Hahn and Borgmann-Winter labs on proteomics and schizophrenia and marvelously defended his thesis today!

A podcast I did previewing my Plenary talk at this years World Parkinsons Congress was just released. The podcast is called Hear! Here! Parkinson’s and originated in Norway. It us co hosted by Eli Pollard and Edgar Valdmanis. It can be heard at www.podbean.com/ew/pb-sdvz8-....

All ready for 3 days of exciting talks and discussions with our colleagues from Rome and Tel Aviv on topics ranging from Parkinson’s disease, ALS, stroke, epilepsy and immunology.

I just had the great honor of speaking with George Ackerman whose advocacy for Parkinson's disease has been tremendous. Our conversation about the role of viruses and PD on his TogetherFor Sharon podcast is available on Spotify. open.spotify.com/episode/4ZSJ...

@raskin.house.gov giving a great and inspirational speech at Philadelphia’s No Kings rally. People from Independence Hall to the Constitution Center.

Appropriate place to end the Philadelphia No Kings march

Our paper discussing templating of alpha-synuclein and how over expression of monomeric (normal) forms of this protein can induce misfolding and induce SNpc DA neuron death was just published in Scientific Reports. nam10.safelinks.protection.outlook.com?url=https%3A...

Very honored to have given this Rising Star interview, where I could talk a bit about myself, my research, my passion for microscopy, and my dream to help find a cure for #LongCovid one day 💔 Link for the full interview: short-link.me/123uR Press release: www.eurekalert.org/news-release...

On this Flag day, let’s remember that this country, founded by immigrants, is made great by the rainbow of people and opinions that strive for a more perfect union. Patriotism is not owned by one group and despite efforts at this small blip in time never will be.

Congratulations to 4 of our @ParkinsonDotOrg Center of Excellence movement disorder physicians, Drs Tsao-Wei Liang, Daniel Kremens and Jeffrey Ratliff (neurology) and Ashwini Sharon (neurosurgery) on being named 2025 top docs by Philadelphia magazine.

Congratulations Jefferson JCLS Class of 2025! Proud of all our Neuroscience graduates and their accomplishments on the road to their PHD, MD, and MS degrees! What a wonderful group of new scholars!! Mazel Tov!

Congratulations to the 2025 Department of Neuroscience graduating class. From L to R: Richard Smeyne, PhD, Professor and Chair, Hanni Jafri, MD, PhD (class of 2025, Dalva lab), Matthew Dalva, PhD (currently, Professor, Tulane University),

Jeffery Taubenberger, who gained fame for unearthing samples of the 1918 flu virus, and ultimately sequencing its entire genome, has been named acting director of the NIAID, Science has learned. scim.ag/3EzzUBo

Our paper examining the role of SARS-CoV-2 infection and its link to the development of Parkinson's disease has been published online in npj Parkinsons's disease. The article is open access. rdcu.be/ei1I6.

We are excited to announce the next Journal of Virology seminar series will be live streamed on March 28 at 11 am Central Time. The paper to be presented is journals.asm.org/doi/10.1128/... by Dr. Christine Marizzi and her group asm.org/Biographies/...

I don’t normally post about politics and I say this as an older white male. We need to get rid of this older generation of Dems. We need new vigor to fight for our beliefs. The current admin will keep winning because Crazy has a lot of Energy.

Congratulations to our labs latest PhD graduate, Debotri Chatterjee who successfully defended her thesis entitled “Induction of Parkinsonism Pathology by Different Strains of SARS-CoV-2 in mice”. Now onto the final 2 years of medical school.

Intracranial electrode bending is underrecognized but not random—it correlates with brain stiffness interfaces. Our study shows MR elastography can predict deviations, challenging the idea that bending is inevitable. 🔗 Read the full article here: journals.lww.com/onsonline/ab... #DBS #stereotaxy

Using your wealth for the betterment of mankind. www.forbes.com/sites/phoebe...

Updated flyer for the Philly Friday March 7 @standupforscience.bsky.social science protest, now w/ alt text & a slightly earlier time. Pls mark those calendars, make those signs & share widely #ScienceIsForEveryone #RestThenResist #CallYourRepresentatives #GoBirds #FlyScienceFly

Listening to Super Bowl champion and leader in community activism Malcolm Jenkins at Jefferson’s Salutes Martin Luther King Jr’s vision.

Nothing else needs to be said.

Our lab is looking for a self motivated postdoc to examine the role of infections in the brain, with a particular focus on induction and progression of parkinsonian pathology. The ideal candidate will have experience in immunology/virology. Although a background in neuroscience will be helpful.

I’m 65 years old and still Get excited when I look up In the sky and can see Mars, Saturn and Jupiter.

Fly Eagles Fly. E-A-G-L-E-S. Great for the city. Broad Street by Jefferson is a sea of happy humanity.

Had a delightful in person reunion with @ssclabquips.bsky.social in Philly for her seminar examining risk factors for influenza infection. Discussions will hopefully lead to a new collaboration on neuro effects of astrovirus.

Had a valuable zoom talk with @daniellebeckman.bsky.social on future collaborations examine the role of viruses in the etiology and progression of Parkinson’s disease. Lots of good ideas bantered back and forth. Hopefully will lead to new and exciting research.

So you want to be a scientist? Advice to the young from pioneering astrophysicist Cecilia Payne-Gaposchkin, who discovered that stars were made primarily of hydrogen, illuminating for the first time the chemical composition of the cosmos. 🧪

Today is the first Philadelphia Flyers game for my Granddaughter Sofia.

Day 2 Session 6 on #genes x #metabolism #environment with Kiran Thakur Keenan Walker Badri Vardarajan Caghan Kizil & Guo Luo

Day 2 Session 5 #TCB2025 #innovative approached to Antigen-Specific T cell #discovery for #nextgen #immunotherapies with Ning (Jenny) Jiang Giacomo Oliveira Moshen Khosravi Maharlooei & Suna

Day 2 Session 7 #ImmuneDynamics at #BarrierTissues #gut_brain in #neurodegeneration with Michal Schwartz Soyong Hong Sandro Da Mesquita Elizabeth Bradshaw & Ryan Hobson

hair @WassimElyaman wants you to get ready for this Industry Round-Table at #TCB2025 livestream on WassimElyaman on X @Merck, @SanofiUS, @MontaiHealth, @LeahSibener, @mekapk_kennedy discussing drug discovery & immunotherapy in 🧠✨ #NeuroImmunology #TCB2025Live

Session 3 #peripheralImmune in #neurodegeneration with @rransohoff @MatheoudD @UFHealth Catherine Flores @YaleMed Le Zhang @DallinDressman

Session 2 #TCB2025 #peripheralimmune #mechanisms in #neurodegeneration with @SaligramaLab @HarmsLab Ronald Libiau & @malutansey.bsky.social

Kicking off 2025 with #TCB2025 tcellsbrain.org today in #NYC @Columbia 🤓💪🏼 🧠 🩸

Great morning session at T-Cells in the brain conference at Columbia University. Love these small intense meetings with lots of interactions.

Session 1 #TCB2025 #immunedysregulation in #neurodegeneration w David Hafler Rani Sarkis Wassim Elyaman & Maria Mittelbrunn

On my way to NYC for T-Cells in the Brain symposium at Columbia University. Let’s just combine the complexities of the nervous system with the immune system for 2 days of fun.

I am giving a talk at our translational research retreat for our Farber Neurological Institute this afternoon on the role of viruses in Parkinson’s disease. Historically I link to the 1918 flu pandemic. Regarding mitigation, nothing has changed (look at dates on slide).

Two papers accepted with moderate revisions this week. An early holiday present was that the reviewers of both papers gave insightful and helpful comments that will in the end make them better. Usually I complain (b**tch) about the comments but spent our holiday lunch complementing their comments.

If an #H5N1 pandemic starts tomorrow or in three months, there will be little mystery as to how it happened. The conditions are all there. They have been for a while. So in some ways the more interesting question to me at the moment is: Why aren’t we in a pandemic yet? Story here, 🧵 to come: 🧪#IDSky

Our preprint discussing the parkinsonian impact of two strains of COVID, how this is affected by vaccination and how carrying a LRRK2 mutation worsens pathology and escapes vaccine protection has just posted. The implications of this on public health are significant. biorxiv.org/cgi/content/...

Heads up for our preprint of our studies showing effects of alpha and omicron strains of SARS-CoV-2 on the basal ganglia and how the immune response to this infection is dysregulated in mice carrying the G2919S LRRK2. Also LRRK2 mice do not fully respond to mRNA vaccine but do to a protein vaccine.

Hockey fights cancer night across the NHL. Here @philadelphiaflyers.bsky.social vs Las Vegas Golden knights.

Had a nice reunion with Dr Cory Abate-Shen from Columbia University for her lecture on prostate cancer biology. We were postdocs together at the Roche Institute for Molecular Biology in 1990. Haven’t aged a day.

Now more than ever the world should learn about the life and impact of @stanfordmedicine.bsky.social neuroscientist Ben Barres, the movie is underway! @atqmovie.bsky.social

Gritty @philadelphiaflyers.bsky.social hanging out in the rafters of Wells Fargo Center dropping stuff on unsuspecting fans

With COVID still soaring, flu season in progress and a potential series of mutations making transmission of H5N1 more likely why am I (and maybe 5%of others) still the only ones masking on public transit. I just am perplexed.

What is scary is how quickly our lab’s papers on the neurological effects of the H5N1 virus are starting to be rediscovered. The A/VN/1203/04 strain was bad. Mammalian brains with this strain seem to be worse off based on some slides I have seen.