Thrilled to introduce our next act 🎭 in @cp-molcell.bsky.social sciencedirect.com/science/arti... led by @glangin.bsky.social We uncover how proteotoxic stress is integrated across compartments, controlling proteasome activation ⚖️ vs photosynthesis repression 🌱 🧵(1/6) #proteostasis

Congratulations @glangin.bsky.social & @suaybuestuen.bsky.social lab!!! You guys are on 🔥 🔥 🔥

Online Now: Proteotoxic stress response is governed by ER-associated sorting of proteasome transcriptional activators Online now:

Thrilled to see my main PhD project finally online @MolCell !! 🥳🌱🧬 If you want to know how the plant proteasome activators are sorted in a proteasome-dependent manner and how they coordinate transcriptional response during proteotoxic stress, please have a read ! 🤓 www.cell.com/molecular-ce...

Looking forward to hearing more about this nice story next week at @ibmp-cnrs.bsky.social!

New post on our homepage ✍️🌱 The story behind our P-body paper in 𝘚𝘤𝘪𝘦𝘯𝘤𝘦 𝘈𝘥𝘷𝘢𝘯𝘤𝘦𝘴 🦠 www.science.org/doi/10.1126/... A ~9-year journey—from “just try it” to uncovering how pathogens hijack translation • hidden gems 💎: 𝘗-𝘣𝘰𝘥𝘺 𝘢𝘶𝘵𝘰𝘱𝘩𝘢𝘨𝘺 𝘳𝘦𝘤𝘦𝘱𝘵𝘰𝘳, 𝘛𝘖𝘙 𝘪𝘯𝘢𝘤𝘵𝘪𝘷𝘢𝘵𝘪𝘰𝘯 𝘣𝘺 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 & 𝘌𝘙 𝘴𝘵𝘳𝘦𝘴𝘴 ✨

Here’s the press release by @ruhr-uni-bochum.de for our newest publication 🧬✨ “Bacteria use P-body condensates to attenuate host translation during infection” How pathogens rewire host translation via condensates 🔄🌱 #plantscience #proteostasis www.science.org/doi/10.1126/...

And if you want to quickly know more about it, here's a small thread we wrote when it was first preprinted 🧵

Who would have thought, five years ago when I first looked at P-bodies under the microscope, that this journey would lead here. 🔬 Very happy to see this work finally out in #ScienceAdvances. Proud of this collaborative effort and grateful to everyone involved. 👏🏻🎉

Bakterien tricksen das Immunsystem von Pflanzen aus, um sie zu infizieren. Dieses Wissen könnte helfen, resistentere Pflanzen zu entwickeln.

🚨 Paper out now in #ScienceAdvances @science.org 🌱🦠 Pathogens don’t just target protein degradation—they also hijack host translation. "Bacteria use P-body condensates to attenuate host translation during infection" ⚖️♻️ led by @manuelgonzalezfuen.bsky.social www.science.org/doi/10.1126/...

Come to Bochum 🌱 — we’d love to host all #plantscience peeps! From biotic interactions 🦠 to #proteostasis ♻️ and development 🌿, there’s something for everyone. Looking forward to inspiring science & great conversations ✨ More info here: botanik-tagung.de

Autophagy acts as a spatial organizer of cell-type-specific plant immunity theustunlab.com/2026/04/12/a... www.biorxiv.org/content/10.6... #proteostasis #plantscience #plantimmunity #theustunlab

Autophagy acts as a spatial organizer of cell-type-specific plant immunity theustunlab.com/2026/04/12/a... www.biorxiv.org/content/10.6... #proteostasis #plantscience #plantimmunity #theustunlab

Preprint alert 🚨 (1/10) 🧵 𝘈𝘶𝘵𝘰𝘱𝘩𝘢𝘨𝘺 𝘪𝘴 𝘢 𝘱𝘢𝘳𝘢𝘥𝘰𝘹 𝘪𝘯 𝘱𝘭𝘢𝘯𝘵 𝘪𝘮𝘮𝘶𝘯𝘪𝘵𝘺: It can promote resistance, susceptibility, or restrict cell death 🤯 So what is its actual role? We show it acts as a spatial organizer of immunity across cell types 🌱🦠 #proteostasis www.biorxiv.org/content/10.6...

So excited to finally share this😃

It will be the first title - as it seems to inspire everybody 😊 #preprint submission ongoing 🤩

It took me an entire day but was worth it - get back to your old hobbies, it‘s amazing 💚

Perfect easter weekend occupation #sciart

yesterday we kicked off the celebrations (hopefully many more to come☺️) with our favorite lab drink - espresso martini - my alternative career plan was approved by @shanshuo.bsky.social 😅

When you cannot decide between two titles...excited for our #preprint 🥳 #teaser

Registration now open! 2026 #EMBO #Ubiquitin Workshop set in stunning Monopoli, Puglia 🇮🇹 Cutting edge science, great speakers, short talk opportunities, travel awards Limited spaces. Dont miss out - register early! Registration & more info: meetings.embo.org/event/26-ubi...

The feeling of getting super excited because you’re about to finish — and soon preprint — a paper you’ve been working with @shanshuo.bsky.social on for 5 years… indescribable 🥳. #preprint 🌱 #PlantScience #autophagy ♻️ #immunity #proteostasis #ERCStG #theustunlab

Spring in full swing in Germany 🌱🌸 …and in our minds too—new ideas, fresh energy, exciting science ahead and soon a new #preprint from @theustunlab.bsky.social #SpringVibes #PlantScience #theustunlab

Who wants some fantastic #proteostasis cookies (made by our bachelor student Nea)? So great to celebrate recent accepted papers in the group - hope we can continue celebrating our own little achievements 🤗 #theustunlab

Manuel González-Fuente from the Ruhr-Universität Bochum will tell us how bacteria exploit plant P-bodies to attenuate host translation during infection #MBP2026

Check out Manuel's work on P-bodies and biotic stress www.biorxiv.org/content/10.1... #MBP2026

Now our very own @manuelgonzalezfuen.bsky.social from @theustunlab.bsky.social who will talk about his exciting findings on how bacteria exploit P-body condensates to attenuate immune-related protein translation (see also our preprint below 👇) #MBP2026 #proteostasis www.biorxiv.org/content/10.1...

The #MBP2026 in Hennef is about to start! We have three days filled with exciting science #plantsci

On our way to the #MBP2026 meeting @theustunlab.bsky.social member @manuelgonzalezfuen.bsky.social will talk about P-bodies/immunity & @seedbarrett.bsky.social will present his project on P-bodies/ABA - since we all 💚 P-body condensates they also made it on our updated logo 😅 theustunlab.com

We just updated our lab homepage „Plant #Proteostasis and its role in stress adaptation“ Check it out: theustunlab.com

My new favorite word : "pre-accept" - more to come soon here 🥳

We recently celebrated the 7th anniversary of @theustunlab.bsky.social with a barbecue! Our journey began in Tübingen in September 2018 and has continued in Bochum since 2022. Excited to see what the coming years will bring!

7 years ago,I sat outside @zmbp-tuebingen.bsky.social,gathering the courage to begin a new chapter as a group leader. Now in Bochum, I still need that courage to face challenges—both inside & outside the lab—but after all I’m grateful that I still find joy in what I do. #happybirthday #theustunlab

Job alert 📣 Our faculty looks for a Junior Professor W1 with tt to W2 in Membrane Biology! We are looking for #ECRs working on membrane biogenesis,contact sites,composition & other aspects of membranes in 🌱 and other organisms! DM me if you need more details! jobs.ruhr-uni-bochum.de/jobposting/f...

We (@manuelgonzalezfuen.bsky.social @margotraffeiner.bsky.social @shanshuo.bsky.social) had a fantastic #2025ISMPMI in Cologne with lots of amazing science and great networking meeting old friends and new ones. Hope to see you all next time in Jeju/South Korea #2027ISMPMI

Next in the concurrent session “spatial and temporal session” is @type3lab.bsky.social who will talk about their amazing findings on distinct pseudomonas subpopulations that cooperate to colonize plants #2025ISMPMI

Last day of #2025ISMPMI, last poster session: dont miss @shanshuo.bsky.social fantastic poster about how we used a combination of scRNAseq and cell-type specific approaches to reveal the role of autophagy in stomatal & mesophyll immunity during Pseudomonas infection - more info ➡️ P-432 #proteostasis

Last day of #2025ISMPMI, last poster session: dont miss @shanshuo.bsky.social fantastic poster about how we used a combination of scRNAseq and cell-type specific approaches to reveal the role of autophagy in stomatal & mesophyll immunity during Pseudomonas infection - more info ➡️ P-432 #proteostasis

Happy to meet you at poster no. P-405 and to talk about my project at #2025ISMPMI this afternoon! 🌿

If you wanna dive into the world of #proteostasis and its role in plant immunity, visit @margotraffeiner.bsky.social poster (P-405) today. She discovered a novel proteotoxicity regulator (a protease with ubiquitin binding capacities) that plays a role in biotic and abiotic stresses! #2025ISMPMI

Enjoying the free afternoon in Cologne at #2025ISMPMI with @manuelgonzalezfuen.bsky.social @margotraffeiner.bsky.social and Christa 🥂

Now @manuelgonzalezfuen.bsky.social is on stage presenting his exciting project on p-bodies, and how bacteria utilize them to attenuate host translation #proteostasis #2025ISMPMI

@manuelgonzalezfuen.bsky.social explains that eukaryote P bodies contain translationally inactive RNAs. Do pathogens induce the formation of these? Yes! How? Effectors!… that repress ER stress response. Why? Make plants susceptible by reducing translation of immunity genes. #2025ISMPMI

If you want to hear about our latest work at @suaybuestuen.bsky.social's lab on pathogen manipulation of host translation and P-bodies at #2025ISMPMI, pass by my presentation today at 12:20 in the concurrent session "Effector interference mechanism" (Room M+N).

We start with the concurrent session: @lauramepul.bsky.social from @geminiteamlab.bsky.social is introducing the plant-virus interactions session - looking forward to some exciting talks #2025ISMPMI

Next in the plenary session of #ISMPMI is @geminiteamlab.bsky.social who will take us in the virus world 🤩 Looking forward to a fantastic talk!

@manuelgonzalezfuen.bsky.social will talk about how bacteria exploit P-bodies to attenuate host translation @margotraffeiner.bsky.social presents a novel proteotoxicity regulator and its role in plant immunty @shanshuo.bsky.social will emphasize the role of autophagy in stomatal immunity

If you’re interested in the role of #proteostasis in plant immunity and how pathogens manipulate it visit our contributions at #2025ISMPMI @manuelgonzalezfuen.bsky.social will talk on Tuesday in the effector interference session @shanshuo.bsky.social (P-432) @margotraffeiner.bsky.social (P-405)