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Unique opportunity to engage in cutting-edge laboratory research, receive guidance from an exceptional mentor, and join a vibrant Institute!

I’m happy to share that our work, “BUB1B monoallelic germline variants contribute to prostate cancer predisposition by triggering chromosomal instability,” has been selected for the Portuguese Society of Human #cancergenetics #prostatecancer

Former supervisors to well succeeded international postdocs returning to Portugal applying for senior postdoctoral (not PI positions) 🇵🇹

There's not long left for you to submit your abstract for our Overactivation of Oncogenic Signalling as a Potential Cancer Treatment Strategy conference! If your research falls into any of these categories, don't miss your opportunity to be included in this conference: eacr.org/conference/o...

Thinking of applying to join us as a new Group Leader? Check out this video: @sylvaindelaunay.bsky.social & @giampazolias.bsky.social, two of our current Group Leaders, in conversation with our Director @turajliclab.bsky.social 🗓️ Apply by 2nd Nov Visit - www.cruk.manchester.ac.uk/career/new-g...

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

Applying for fellowships/grants: You( left) and the other candidates (right).

If there were ways to quantify the impact of making negative results (or “incomplete stories”) available, I believe we’d be amazed at how much more efficient scientific research could become!

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Yep… pretty much it! Backpacking well past socially acceptable deadline for financial and professional stability.

🚨 New Blog Post 🚨 @luisa86ferreira.bsky.social was one of 5 Conference Correspondents for @helloeacr.bsky.social at #EACR2025 She shares her reflections from the conference & spotted some familiar #Manchester #CancerResearch faces amongst the attendees 👇 www.cruk.manchester.ac.uk/news/researc...

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An enormous honour! Thank you @embo.org and @helloeacr.bsky.social! This talk was only possible because of the amazing talent of @caldaslab.bsky.social and past #Caldasians!

More familiar faces showcasing their work at #EACR2025! #ipoporto #i3S

Familiar faces showcasing their work at the #EACR2025 #CRUKMI

Symposium: ecDNA Andreas Ventura showed that normal primary cells can propagate ecDNAs, and that ecDNAs can promote transformation and tumorigenesis in vivo, using elegant in vitro and in vivo models of ecDNA. Fantastic work! #EACR2025

Symposium: EC DNA Fantastic talk by Paul Mischel highlighting the multitude of mechanisms by which ecDNAs drive tumour heterogeneity and resistance to therapy! #ESCR2025

Fantastic talk by Samra Turajlić on tumour evolution in ccRCC! We could not be prouder at Cancer Research UK Manchester Institute of our new director after such an outstanding presentation! 👏🏻👏🏻👏🏻 #EACR2025 #CRUKMI -

Beatriz Monteverde presented her proffered paper on Integrative multi-omic approach to identify patterns of immune selection in primary breast tumours! #EACR2025

Paola Scaffidi, PhD shared with us how disruption of the epigenetic regulatory network increases the tolerance of cancer cells and how these "transcriptionally numb" cells increasing the chance of long-term adaptation! - Epigenetic dysregulation and cancer evolution! #EACR2025

Clare Isacke shared fascinating research on how the aged microenvironment promotes relapse in ER+ breast cancer, with a spotlight on the role of PDGF-C. A powerful link between ageing and metastasis! #EACR2025

A truly "out of the box" talk on cockle transmissible cancers, horizontal gene transfer, and instability of mitogenomes by Alicia L. Bruzos, PhD! 🌊🦪 Challenging paradigms and expanding our understanding of cancer beyond humans! #EACR2025

Ivaska Johanna shared powerful insights into how dynamic regulation of integrin β1 phosphorylation supports breast cancer cell invasion. Fundamental biology at the heart of cancer research! #EACR2025

Sam Au introduced us to the SHEAROSOME—tumour cells shedding at capillary bifurcations—and its key role in driving metastasis. A fascinating look into the physical forces behind cancer spread! #EARC2025

Amazing talk by Sheila Stewart on how senescent fibroblasts drive breast cancer progression! #EACR2025

Full house to attend to Eileen White keynote lecture on Cancer Metabolism with special focus on cancer cachexia! #EACR2025

Jan H. Hoeijmakers shared mindblowing insights on how caloric restriction impact on DNA damage response, cancer, and ageing! Also unexpected effects of carbohydrate and fat vs protein intake. (Less) food for thought —literally! #EACR2025

An exciting cohort of top Portuguese scientists leading the way in cancer research! 🇵🇹 Proud to witness such excellence and innovation driving the future of oncology. #EACR2025 Chairs: Alberto Bardelli Carmen Jeronimo (#ipoporto)

ASPIC - Joint Symposium at EACR 2025 Congress - Lisbon Carla Oliveira has shown us today a real tour of force on hereditary gastric cancer and the necessity to shift focus towards prevention in asymptomatic carriers of cancer-predisposing variants! #Preventable #EACR2025 #i3S

ASPIC - Joint Symposium at EACR 2025 Congress - Lisbon João Taborda Barata presented us today with how IL7/IL-7R subvert lymphoid development towards leukemia. Fascinating insights into the mechanisms behind leukemia initiation! #EACR #GIMM

ASPIC - Joint Symposium at EACR 2025 Congress - Lisbon Rita Fior presented the powerful Zebrafish Avatar-test for forecasting clinical response! Excited to see the outcomes of the ongoing multicentric clinical trial using this innovative model. Exciting science! #EACR2025 #Champalimaud

ASPIC - Joint Symposium at EACR 2025 Congress - Lisbon Amazing talk by Bruno Santos Silva ( #GIMM ) on the role of γδ T cells in cancer immunotherapy and how these unique immune cells could transform cancer treatment! #EACR2025

Registration is open for our Signalling Circuits in Cancer virtual conference! We're welcoming researchers from around the world to explore the dynamic signalling pathways that drive cancer development and progression. Submit your abstract and register: eacr.org/conference/s...

🌟 Exciting insights! Our group leaders and PIs from @uom-dcs.bsky.social, at various career stages, reflected on key decisions and the challenges of transitioning to independent researchers. Special thanks to @luisa86ferreira.bsky.social and Nasir Haider for revitalizing our STAy Committee! 🙌

Luminescence! Fireflies — one of scientists’ best friends — lighting up the countryside! 🤩

Also featured in News & Views! 🤩 www.nature.com/articles/s41...

Pretty impressive work! 👍🏻