Tuesday 25.11 13:00 CET we are happy to host Prof. Leon Schulte (rna-lab.org) @schultelab.bsky.social join us for an exciting talk "Multi-omic Dissection of Regulatory lncRNA-Protein Networks in Innate Immunity" thanks @rnasociety.bsky.social @imbb-forth.bsky.social us02web.zoom.us/meeting/regi...

Our latest study is now out in @narjournal.bsky.social‬: we identify a post-transcriptional bottleneck in interferon gamma signaling that hinges on proper maturation of JAK2 mRNA. Paper: academic.oup.com/nar/article/...

How do long noncoding RNAs help macrophages fight bacteria? We built a whole atlas to explore this question — and it’s now published in Nature Communications! 🔗 rdcu.be/em7aM #lncRNA #macrophage #immunology

We also built SMyLR, a searchable online resource for the immune-lncRNA community: Explore pathway dependencies, subcellular localization, and protein interactors of hundreds of lncRNAs in macrophages: 🔍 rna-lab.org/smylr/ More info in our paper: 🔗 rdcu.be/em7aM #lncRNA #openscience #macrophage

Meet GRADR: our new approach to chart lncRNA–protein interactions transcriptome-wide. By combining gradient profiling and RNA-binding proteomics, GRADR reveals which lncRNAs engage which protein machineries. 📘 Step-by-step protocol included in: 🔗 www.nature.com/articles/s41... #lncRNA #methods

We’re now on Bluesky! This space will share updates from our lab, covering RNA biology, macrophage immunology, and long noncoding RNAs. Follow along for papers, resources & insights from the bench. #lncRNA #macrophage #immunology #RNA #biomed #openscience