How does rapid, transparent sharing accelerate #Parkinsons research? 🧪 Kicking off our #OpenScienceWeek highlights, Cole Sitron, PhD (@pelletfraction.bsky.social) of CRN Team Harper, explains how Open Science lays the foundation for faster, more equitable discovery ⬇️ #ScienceForAll

Why are α-synuclein aggregates in Parkinson’s disease (PD) toxic at the cell biological level? Our new study shows that α-syn fibrils hijack the ESCRT membrane repair system, triggering a feedback loop that worsens aggregation. You can find it at: authors.elsevier.com/sd/article/S...

A new preprint from CRN Team Harper found that the depletion of ESCRT-III weakens membranes, allowing alpha-synuclein aggregates to spread and cause damage. Authors: @harperlabhms.bsky.social @harvardcellbio.bsky.social @pelletfraction.bsky.social 🔗 Check out the full #preprint: shorturl.at/69Ha6