hi everybody, asmita here back at it again with another preprint for your attention. excited to share our new fluorogenic speed probes that enable whole cell 3D imaging! 🔬

Please check out our newest work on fluorogenic speed imager probes, in which we combine the strengths of speed-optimized imagers and fluorogenic imagers. #SuperResolution #DNAPAINT #microscopy www.biorxiv.org/content/10.6...

I had a lot of fun putting this together with @suminkim.bsky.social and @andersshansen.bsky.social! Glad to have had the chance to work on it!

Thanks also to @lucagiorgetti.bsky.social and @djost-physbiol.bsky.social for the invitation and for putting together a very interesting themed issue - the other reviews in the issue can be found here www.sciencedirect.com/special-issu...

Happy to share our new review on Polycomb-mediated 3D chromatin interactions! Thanks to @mileshuseyin.bsky.social and @andersshansen.bsky.social for great discussions throughout the process :)

Very cool!

The Sosa Lab is going to #SfN25 and actively recruiting ✨postdocs✨ with systems neuroscience experience! We study both fundamental memory processes and how memory changes during pregnancy and postpartum. If you are interested in meeting at SfN, please email me! www.sosaneurolab.com/join/postdoc...

❤️

Excited to be a part of this amazing community!

Excited to share my first preprint from the @andersshansen.bsky.social lab! It's got genomics, AI, and biology - all wrapped up in a great paper. Also very grateful to my amazing collaborator, Fan, for all his hard work. Please check it out and let me know what you think! tinyurl.com/bdfvtd6f

(1/n) New preprint from @claricehongky.bsky.social Fan Fang Varshini Ramanathan in collab w Jie Liu. Q: How do we get ultra-high-res 3D genome maps? A: New deep learning model, Cleopatra. Cleo trains on Micro-C, fine-tunes on RCMC, and predicts genome-wide 3D maps at ultra-high resolution.

(1/n) Thread @matteomazzocca.bsky.social @domenicnarducci.bsky.social Simon Grosse-Holz @jessematthias.bsky.social preprint Q: how does chromatin move? Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...

1/ Super excited to share my first preprint from @andersshansen.bsky.social Lab! We used MINFLUX to track chromatin (H2B-Halo and Fbn2 locus) at an unprecedented 200 μs, then combined it with SPT to span μs-minutes (H2B) or SPT & Super-Res Live-Cell Imaging (SRLCI) to span μs-hours (Fbn2)