HöbartnerLab UniWue
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Nucleic Acid Chemistry Lab
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HöbartnerLab UniWue
Nature Chemical Biology
9 months ago
A new paper from the Hoebartner Lab @UniWue
@chlab.bsky.social
reports the crystal structures of the ribozyme SAMURI, revealing the mechanism of its methyltransferase activity and site-selectivity
www.nature.com/articles/s41...
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Structure and catalytic activity of the SAM-utilizing ribozyme SAMURI - Nature Chemical Biology
Crystal structures of the ribozyme SAMURI reveal the alkyltransferase mechanism and show N3-modified adenosine and dealkylated cofactor in the active site, allowing for a comparison with riboswitches ...
https://www.nature.com/articles/s41589-024-01808-w
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