Laim Zizmare
@laimziz.bsky.social
📤 237
📥 188
📝 12
I’m all about metabolites, biomarkers, bioanalysis, and rocknroll.
reposted by
Laim Zizmare
Oded Rechavi
6 months ago
How your email finds me
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One last time, for now 👋🏼
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6 months ago
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Once an
@emn-metsoc.bsky.social
, always an EMN kind of a night 🙏🏼
#metabolomics2025
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7 months ago
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Catch up dinner with the membership committee of
@metsoc.bsky.social
and friends 🍻🇨🇿
#Metsoc2025
#Metabolomics2025
@emn-metsoc.bsky.social
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7 months ago
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Laim Zizmare
Justin J.J. van der Hooft
7 months ago
#metabolomics
is looking more popular than ever!
#MetSoc2025
Metabolomics Society 🙌
#CompMetabolomics
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Laim Zizmare
Nicholas Rattray
11 months ago
Delighted to see the Metabolomics Society now officially on
@bsky.app
@metsoc.bsky.social
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Look at this amazing work on
#Senescence
Cell Induction Methods with Diverse Metabolic Reprogramming & Underpinning Serine/Taurine Reductive
#Metabolic
Phenotype by the legends Domenica Berardi,
@carolinejohnson.bsky.social
,
@nikrat.bsky.social
in Aging Cell
onlinelibrary.wiley.com/doi/10.1111/...
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Senescence Cell Induction Methods Display Diverse Metabolic Reprogramming and Reveal an Underpinning Serine/Taurine Reductive Metabolic Phenotype
This study reveals that in vitro senescence induction methods significantly influence intracellular biomolecular profiles, showing both shared and unique metabolic responses. A novel bioanalytical pi....
https://onlinelibrary.wiley.com/doi/10.1111/acel.70127
7 months ago
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Laim Zizmare
Oded Rechavi
7 months ago
Your 7 coauthors who didn't contribute to the paper
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Prague, here we come
#Metabolomics2025
Looking forward to meet familiar faces and new friends!
@emn-metsoc.bsky.social
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7 months ago
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Laim Zizmare
EMN Metabolomics Society
8 months ago
Join us at Metabolomics 2025 for our workshop -> W10: EMN – MetaboMentors! Grow as a mentor or mentee through insights, tools & global perspectives. 📅 Monday, June 23rd, 8:15 - 10:15 in South Hall 2 🔗
www.metabolomics2025.org/workshops
🎤
#EMN
#MetaboMentors
#Mentorship
#Metabolomics2025
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Laim Zizmare
EMN Metabolomics Society
7 months ago
🧠 Don’t miss the EMN Mentoring workshop (June 23, 8:15 AM, Sth Hall 2) at
#Metabolomics2025
! Get inspired by top scientists who’ve been where you are now.
#Mentorship
#EMN
#MetabolomicsSociety
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Laim Zizmare
Werner Siemens Imaging Center
9 months ago
Team spirit in the Alps🏔️! We are grateful for inspiring discussions, fresh ideas, and amazing company at the WSIC annual department retreat in beautiful Obergurgl🇦🇹. A special thank you to our office team for all their planning efforts 🙌
#WSICRetreat
#ScienceInTheAlps
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Laim Zizmare
Feucht & Leibold Lab
10 months ago
We are
#hiring
!! 🤩 Are you a passionate researcher looking for a PhD or postdoc position in the field of CAR T cell therapies, gene editing and cancer-immune cell interactions? Then apply to join our amazing team in beautiful Tübingen! 📩☀️
www.feucht-leibold-labs.com/vacancies
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Vacancies | Feucht Leibold Lab Tübingen
We are hiring!
https://www.feucht-leibold-labs.com/vacancies
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Laim Zizmare
EMN Metabolomics Society
10 months ago
Attention
#Metabolomics
ECRs!👩🔬 Meet the speakers for our upcoming Virtual Networking event w/ Metabolomics South Africa! Each bring unique insights and expertise — from academia, industry, government, and beyond Check out their bios below! 🌍 📢
#Networking
#ECR
Register here 🔗
tinyurl.com/9kkj85tp
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Laim Zizmare
Oded Rechavi
10 months ago
We continue working on the plans for the "Woodstock of Bioloy 2 & Night science in Prague" meeting and if you don't sign up you're totally crazy. A once in a life time opportunity and it'll be sold out soon. Go to the website and sign up now before it's too late!
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Laim Zizmare
Werner Siemens Imaging Center
11 months ago
A hearty congratulations to our Director, Prof. Dr. Bernd Pichler, for being awarded the prestigious ESMI award🎉🏆
@unituebingen.bsky.social
@siemens-ring.bsky.social
#EMIM2025
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Laim Zizmare
EMN Metabolomics Society
11 months ago
🚨 Abstract deadline alert! 🚨 Friendly reminder to submit your oral abstract before March 6 – don’t miss the chance to showcase your work at hashtag#MetSoc2025! Registration is now open:
lnkd.in/eFZGi4CK
#Metabolomics
#EMN
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reposted by
Laim Zizmare
BioMassSpec
12 months ago
Molecular Profiling of Glioblastoma Patient-Derived Single Cells Using Combined MALDI-MSI and MALDI-IHC
#AC
pubs.acs.org/doi/10.1021/...
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Molecular Profiling of Glioblastoma Patient-Derived Single Cells Using Combined MALDI-MSI and MALDI-IHC
In recent years, mass spectrometry-based imaging techniques have improved at unprecedented speeds, particularly in spatial resolution, and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) experiments can now routinely image molecular profiles of single cells in an untargeted fashion. With the introduction of MALDI-immunohistochemistry (IHC), multiplexed visualization of targeted proteins in their native tissue location has become accessible and joins the suite of multimodal imaging techniques that help unravel molecular complexities. However, MALDI-IHC has not been validated for use with cell cultures at single-cell level. Here, we introduce a workflow for combining MALDI-MSI and MALDI-IHC on single, isolated cells. Patient-derived cells from glioblastoma tumor samples were imaged, first with high-resolution MSI to obtain a lipid profile, followed by MALDI-IHC highlighting cell-specific protein markers. The multimodal imaging revealed cell type specific lipid profiles when comparing glioblastoma cells and neuronal cells. Furthermore, the initial MSI measurement and its sample preparation showed no significant differences in the subsequent MALDI-IHC ion intensities. Finally, an automated recognition model was created based on the MALDI-MSI data and was able to accurately classify cells into their respective cell type in agreement with the MALDI-IHC markers, with triglycerides, phosphatidylcholines, and sphingomyelins being the most important classifiers. These results show how MALDI-IHC can provide additional valuable molecular information on single-cell measurements, even after an initial MSI measurement without reduced efficacy. Investigation of heterogeneous single-cell samples has the potential of giving a unique insight into the dynamics of how cell-to-cell interaction drives intratumor heterogeneity, thus highlighting the perspective of this work.
https://pubs.acs.org/doi/10.1021/acs.analchem.4c03821
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Laim Zizmare
MPI for Biology Tübingen & Friedrich Miescher Laboratory
12 months ago
Celebrating 10 years of @unesco.org's Int'l Day of
#WomenInScience
! We are fortunate to have this inspiring team of leaders. We're proud to champion their contributions to science, along with those from our Postdocs, Technicians, PhD & masters students at MPI-Bio & the FML in Tübingen.
#IDWGS2025
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Laim Zizmare
Females in Mass Spectrometry (FeMS+)
12 months ago
Applications are open for the
#FeMS+
2025 Q2 Empowerment Awards! Thanks
@brukercorporation.bsky.social
for sponsoring! Apply here:
airtable.com/appyGufCIumj...
#TeamMAssSpec
#WomenEmpowerment
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reposted by
Laim Zizmare
EMN Metabolomics Society
12 months ago
🏆EMN Travel Awards are back for
#MetSoc2025
in Prague! EMN Travel Award – Up to 4 grants for graduate (Master’s/PhD) & postdocs. 📍More info:
metabolomics2025.org/awards
#Metabolomics
#EMN
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I didn’t think I would ever say this, but: Latvian made, Golden Globe awarded, Oscar nominated movie (that also has a capybara in it) is finally coming to cinemas in Germany (yes, even Tübingen)! 🥹🥳🐈⬛ keep an eye out for Flow
#Flow
#flowMovie
@gintszilbalodis.bsky.social
🇱🇻
12 months ago
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It’s not the occasion that makes the thief. It only reveals them. -Mario Sergio Cortella
12 months ago
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reposted by
Laim Zizmare
European Commission
12 months ago
Today, we remember all the victims murdered during the Holocaust. We mark the 80 years since the liberation of the Nazi concentration and extermination camp Auschwitz-Birkenau. This memory must be passed to future generations.
#HolocaustRemembranceDay
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reposted by
Laim Zizmare
Manuel Liebeke
about 1 year ago
Happy New Year 🎉 Our collab with Strittmatter lab TU Munich shows the power of
#massspec
to see
#bacteria
in
#tissues
233 bacterial species were mined for markers at different phylogenetic levels. Watch out for those taxon-specifc markers (TSMs) in your
#spatialmetabolomics
tinyurl.com/yza6t32w
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reposted by
Laim Zizmare
BioMassSpec
about 1 year ago
Mass-Guided Single-Cell MALDI Imaging of Low-Mass Metabolites Reveals Cellular Activation Markers
#AdvSci
onlinelibrary.wiley.com/doi/10.1002/...
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Mass‐Guided Single‐Cell MALDI Imaging of Low‐Mass Metabolites Reveals Cellular Activation Markers
The PRISM-MS workflow transforms single-cell mass spectrometry imaging by allowing detailed analysis of low-mass metabolites in large cell populations without metabolite degradation. By introducing n...
https://onlinelibrary.wiley.com/doi/10.1002/advs.202410506
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reposted by
Laim Zizmare
David Broadhurst
about 1 year ago
THe
#metabolomics
starter pack is now up to 75 members. Again, if you would like to be added let me know. Equally if I have put you on the list by mistake let me know.
go.bsky.app/J3VPYKm
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reposted by
Laim Zizmare
Nikolai Slavov
about 1 year ago
Timescales in Cell Biology
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Laim Zizmare
Oded Rechavi
about 1 year ago
When you check on your cell culture after the weekend
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reposted by
Laim Zizmare
Sarah E Hancock
about 1 year ago
The unofficial FeMS starter pack (until they join us on Bluesky :) anyway. If you're a woman working with a mass spectrometer please ask to be added! All women are welcome!
go.bsky.app/PUwu7fr
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Laim Zizmare
Functional Metabolomics Lab
about 1 year ago
Next Tuesday, Nov 19, 5 pm CET / 8 am PST we will have the next
#VMOL
seminar
#mzmine
series on multimodal data processing using mzwizard. And in case you wana watch the last mzmine seminar on non-targeted LC-MS/MS data processing, you can find the recording here:
youtu.be/UnqVtZngzl0
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Laim Zizmare
Bryan Gonzales
about 1 year ago
Researchers in low & middle-income countries face major challenges when conducting
#omics
research. What hurdles do we need to overcome? How do we do it? How do we make research fair and equitable? See our latest paper in Nature Biotechnology to understand these barriers and enablers:
rdcu.be/dK4Hb
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Barriers and enablers to the effective implementation of omics research in low- and middle-income countries
Nature Biotechnology - Addressing the hurdles and opportunities associated with omics research in low- and middle-income countries may inform strategies for its effective execution, and thus...
https://rdcu.be/dK4Hb
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Research planning and inspiration weekend at Ringberg-Tegernsee ✨
about 1 year ago
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