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ChatGPT Health performance in a structured test of triage recommendations | Nature Medicine ChatGPT Health was launched in January 2026 as OpenAI’s consumer health tool and has reached millions of users. Here we conducted a structured stress test of triage recommendations using 60 clinician-authored vignettes across 21 clinical domains under 16 factorial conditions, yielding 960 total responses. Performance followed an inverted U-shaped pattern, with the most dangerous failures concentrated at clinical extremes—nonurgent presentations (35%) and emergency conditions (48%). Among gold-standard emergencies, the system undertriaged 52% of cases, directing patients with diabetic ketoacidosis or impending respiratory failure to 24–48 h evaluation rather than the emergency department, while correctly triaging classical emergencies such as stroke and anaphylaxis. When family or friends minimized symptoms, indicating anchoring bias, triage recommendations shifted significantly in edge cases (odds ratio = 11.7, 95% confidence interval = 3.7–36.6), with the majority of shifts toward les https://doi.org/10.1038/s41591-026-04297-7