Heemskerk Lab (@heemskerklab.bsky.social)

After being reviewed as a preprint in Elife our paper about endogenous FGF signaling in 2D human gastruloids is now published in Development: journals.biologists.com/dev/article-...

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Endogenous FGFs drive ERK-dependent cell fate patterning in 2D human gastruloids Summary: In a 2D gastruloid model for human gastrulation, FGF4 and FGF17 signal through basolateral receptors to induce primitive streak-like cells and derivatives, potentially restricted by FGF8. https://journals.biologists.com/dev/article-lookup/doi/10.1242/dev.205459