Amy Thompson
@amyjayyyne.bsky.social
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Postdoc crystallographer chilling at synchrotrons and screaming at computers.
reposted by
Amy Thompson
Adam Crawshaw
17 days ago
VMXm has postcards! Available from the beamline or a member of the VMXm team if you see us at conferences. Do reach out to us for your microcrystal X-ray diffraction experiments.
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reposted by
Amy Thompson
Adam Crawshaw
about 1 month ago
The first
@diamondlightsource.bsky.social
MX Newsletter is here! Including the latest news from the MX beamlines, helpful info about shutdowns, runs and training opportunities as well as useful tips and tricks for making the most of the MX beamlines at Diamond.
www.diamond.ac.uk/Instruments/...
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MX-Newsletter - - Diamond Light Source
This is a periodical newsletter which covers news, updates, and announcements from the MX village. MX-village constitutes of seven macromolecular crystallography beamlines and other associated facilit...
https://www.diamond.ac.uk/Instruments/Mx/Newsletter.html
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reposted by
Amy Thompson
IUCrJ
about 1 month ago
Peter Smyth et al.: Time-resolved serial synchrotron and serial femtosecond crystallography of heme proteins using photocaged nitric oxide
##TimeResolvedXRayCrystallography
##SerialCrystallography
@Uni_of_Essex...
##IUCr
https://journals.iucr.org/paper?S2052252525006645
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Time-resolved serial synchrotron and serial femtosecond crystallography of heme proteins using photocaged nitric oxide
We demonstrate the application of a nitric oxide releasing photocage system for time-resolved serial crystallography studies of two heme containing proteins using a fixed target sample delivery system. Optimal parameters for successful photocage activation and nitric oxide release are explored.
https://journals.iucr.org/paper?S2052252525006645
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reposted by
Amy Thompson
Mike Hough
about 1 month ago
New paper describing use of photocaged nitric oxide for time resolved crystallography within fixed targets at XFEL and synchrotron - PhD work of Pete Smyth & Lewis Williams - great collaboration with
@jarworrall.bsky.social
, beamline I24 and SACLA. Funded by BBSRC
journals.iucr.org/m/issues/202...
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Time-resolved serial synchrotron and serial femtosecond crystallography of heme proteins using photocaged nitric oxide
We demonstrate the application of a nitric oxide releasing photocage system for time-resolved serial crystallography studies of two heme containing proteins using a fixed target sample delivery system...
https://journals.iucr.org/m/issues/2025/05/00/car5004/index.html
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reposted by
Amy Thompson
Adam Crawshaw
about 2 months ago
Registration is open for the September on-site MX user training. If you are an MX user of
@diamondlightsource.bsky.social
then please to apply to attend - spaces are limited. You'll have the opportunity to visit and learn about all the MX beamlines, data analysis as well as all things logistics.
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On-site MX User Training: September - - Diamond Light Source
Training sessions for users of the Macromolecular Crystallography (MX) beamlines
https://www.diamond.ac.uk/Home/Events/2025/MX-BAG-Training.html
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Having a great time in York teaching crystallographic data reduction - great to see the students so engaged and asking really good questions!
#ccp4
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2 months ago
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Wrapped up another conference for the year at the
#ACA2025
- thanks to the organisers for putting on a great conference! I greatly enjoyed bringing my work on clustering 🐮🐷🤷♀️ to a new audience - the conference dinner had some pretty neat views too!
2 months ago
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reposted by
Amy Thompson
Structural Biology
4 months ago
Enhancements of the intensity-clustering algorithms available within DIALS and utilized by xia2.multiplex are described and demonstrated
#MultiCrystalDataSets
#DataProcessing
#Clustering
doi.org/10.1107/S205...
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reposted by
Amy Thompson
Mike Hough
4 months ago
Paper describing clustering methods to separate subtle structural differences in populations of protein crystals - with application to polymorphs, ligand binding.. - led by Amy Thompson
@amyjayyyne.bsky.social
with VMXi,I24 and Data Analysis at
@ddiamond.bsky.social
journals.iucr.org/d/issues/202...
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Enhanced intensity-based clustering of isomorphous multi-crystal data sets in the presence of subtle variations
Bovine, porcine and human insulin data sets are isomorphous in terms of unit cell and symmetry. Through enhancements to the multi-crystal clustering methods in DIALS, species-pure data sets are automa...
https://journals.iucr.org/d/issues/2025/06/00/rr5252/index.html
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Thrilled to have this work published! Thanks to some awesome teamwork, we've demonstrated improvements in multi-crystal data clustering by automatically separating 🐮🐷🧑🔬
#multicrystal
#clustering
#crystallography
doi.org/10.1107/S205...
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Enhanced intensity-based clustering of isomorphous multi-crystal data sets in the presence of subtle variations
Bovine, porcine and human insulin data sets are isomorphous in terms of unit cell and symmetry. Through enhancements to the multi-crystal clustering methods in DIALS, species-pure data sets are automa...
https://doi.org/10.1107/S2059798325004589
4 months ago
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This was my first step into the world of XFELs - a great team to collaborate with!
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6 months ago
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Having a great time at the BCA - thanks to the organisers for putting on a great conference and inviting me to present!
add a skeleton here at some point
6 months ago
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reposted by
Amy Thompson
David Aragão 🔶
6 months ago
Our own
@amyjayyyne.bsky.social
from
@diamondlightsource.bsky.social
presenting VMXi at
@crystallography.org.uk
. Great talk!
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reposted by
Amy Thompson
Martin Walsh
6 months ago
Participants in the annual serial crystallography workshop for graduates student some funded by our
@wellcometrust.bsky.social
PhD program have got homework to do in the evening time ….
@diamondlightsource.bsky.social
@instruct-eric.bsky.social
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reposted by
Amy Thompson
7 months ago
theconversation.com/crystals-can...
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Crystals can’t bend – or can they? New research sheds light on elusive ‘flexible crystals’
Crystals are supposed to be hard and brittle. But when we make them bendy, they help reveal the secrets of how elastic materials work.
https://theconversation.com/crystals-cant-bend-or-can-they-new-research-sheds-light-on-elusive-flexible-crystals-248141
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Super exciting to have this finally out! It was great to have different fields coming together for this collaboration
add a skeleton here at some point
7 months ago
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