From #drug cabinet → gut #microbiome: screening 312 therapeutic compounds, we mapped 4.6 million microbial protein-level responses to reveal how our drugs don’t just target us, they hit our gut microbes too. rdcu.be/eMmcT

The microbiologist's guide to metaproteomics onlinelibrary.wiley.com/doi/full/10.... #Bioinformatics #microbiome #metaproteomics #proteomics #MS

Are you new to #metaproteomics but don't know where to start? Then this guide, written by experts of the Metaproteomics Initiative, is for you! onlinelibrary.wiley.com/doi/full/10....

🚀 Interested in the interactions of xenobiotics with the gut microbiome? Join us @quadraminstitute.bsky.social to apply precision microbiome assays to xenobiotics. Apply by 28 May 2025. 👉 quadram.ac.uk/vacancies/gr... #microbiome #PrecisionNutrition #metaproteomics #metabolics #metagenomics

The oral microbiome is linked to various inflammatory conditions, including IBD. However, analyzing functional changes at the protein level has been challenging due to host protein interference. 🧵 1/3

I couldn’t be prouder—this is the work of the very first master's student that I've supervised. Salivary metaproteomics is tricky due to host/debris interference. Yuan et al. developed a microbial cell enrichment step and achieved cleaner data with better insights. www.nature.com/articles/s41...

Metaproteomics deserves a dedicated β-diversity metric: microbiolly.wordpress.com/2025/03/19/p...

🚨 We mapped 4.6M #microbial protein responses to 312 compounds, uncovering 3 distinct functional gut #microbiome states and revealing how neuropharma triggers deep shifts (lower functional redundancy, higher #AMR proteins). www.biorxiv.org/content/10.1...

🦠 In #metaproteomics, proteins are often treated as independent features, ignoring their ecological relationships. 🌱 We developed PhyloFunc, a beta diversity metric that integrates phylogeny into functional distance calculations, offering a more ecologically meaningful way to compare microbiomes.

🎉 Excited to share this amazing Metaproteomics Initiative community effort aims to make metaproteomics accessible and easy to use for microbiome researchers. Grateful for this unforgettable journey of collaboration! 🌍🔬 #Metaproteomics #Collaboration #Science chemrxiv.org/engage/chemr...

If you want to get started with #metaproteomics , this guide is a good starting point. This was an amazing metaproteomics community effort to get all the key information together led by Tim Van Den Bossche and Leyuan Li chemrxiv.org/engage/chemr...