Alexander Tesmer
@alexandertesmer.bsky.social
📤 28
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PhD Neuroscience ‘25. Burdakov lab alumni. Metabolism and cognition in the hypothalamus.
In mice, orexin neurons multiplex the encoding of rapid body-movements with slow changes in blood glucose. The extent to which these neurons correlate with movement across behavioral and metabolic states surprised us! Now a Version of Record in
@elife.bsky.social
.
doi.org/10.7554/eLif...
6 months ago
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reposted by
Alexander Tesmer
CMC lab
8 months ago
In our Learning Club
@cmc-lab.bsky.social
tomorrow (= July 3rd, Thursday, 2 PM CET),
@alexandertesmer.bsky.social
will tell us about his recent paper (
bsky.app/profile/alex...
). If you'd like to attend, send an empty email to
[email protected]
to get the link!
add a skeleton here at some point
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Hunger-driving AgRP neurons are REM-active, and similarly re-activate during cataplexy. Hot off the press from the Burdakov lab!
www.biorxiv.org/content/10.1...
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A rapid arousal brake on hunger neurons and its release in narcolepsy
Human sleep-wake disorders are often accompanied by eating disorders; the reasons for this apparent interplay between hunger and arousal remain unclear. Pupil-linked arousal fluctuates second-by-secon...
https://www.biorxiv.org/content/10.1101/2025.03.07.642010v1
12 months ago
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Policy complexity is expensive. How does the brain regulate its investment of cognitive capacity? Our newest paper is on BioRxiv! We examine hypothalamic orexin (and MCH!) -producing neurons for their role in regulating the complexity decision policies.
www.biorxiv.org/content/10.1...
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Neurometabolic signaling and control of policy complexity
Cognition and adaptive behavior emerge from neural information processing. This must operate within finite metabolic constraints, since neural information processing is metabolically expensive. While ...
https://www.biorxiv.org/content/10.1101/2025.02.24.639890v1
12 months ago
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Reviewed preprint is online in
@elife.bsky.social
: Reviewers raised some important points, revisions coming soon! Orexin population activity precisely reflects net body movement across behavioral and metabolic states
doi.org/10.7554/eLif...
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Orexin population activity precisely reflects net body movement across behavioral and metabolic states
https://doi.org/10.7554/eLife.103738.1
about 1 year ago
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reposted by
Alexander Tesmer
bioRxivpreprint
over 1 year ago
Distinct bandwidths of orexin neuron activity independently encode body movement and metabolic state https://www.biorxiv.org/content/10.1101/2024.08.13.607750v1
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Distinct bandwidths of orexin neuron activity independently encode body movement and metabolic state https://www.biorxiv.org/content/10.1101/2024.08.13.607750v1
Hypothalamic orexin/hypocretin neurons (HONs) are key orchestrators of metabolism and adaptive behav
https://www.biorxiv.org/content/10.1101/2024.08.13.607750v1
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