David Winchester
@drdavemd.bsky.social
📤 96
📥 85
📝 233
Cardiology & health services research. Posts do not reflect positions of my employers. K index 1.42.
"In this meta-analysis including individual-patient data from five RCTs, beta-blocker...did not reduce...death..., myocardial infarction, or HF in pts with an LVEF>=50% after MI without other indications for beta-blockers."
www.nejm.org/doi/full/10....
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Beta-Blockers after Myocardial Infarction with Normal Ejection Fraction | NEJM
The benefit of beta-blockers after myocardial infarction in patients with a preserved left ventricular ejection fraction (LVEF) is unclear. We conducted a meta-analysis at the individual-patient le...
https://www.nejm.org/doi/full/10.1056/NEJMoa2512686
2 days ago
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Transforming Cardiovascular Leadership Through Strategic Investment
www.jacc.org/doi/10.1016/...
@jaccjournals.bsky.social
@chriskramermd.bsky.social
@accintouch.bsky.social
#cardiosky
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Transforming Cardiovascular Leadership Through Strategic Investment:
https://www.jacc.org/doi/10.1016/j.jacc.2025.10.010
2 days ago
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Myocardial blood flow for ischemic heart disease, a great review of different imaging modalities
www.jacc.org/doi/epdf/10....
@jaccjournals.bsky.social
#cardiosky
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Myocardial Blood Flow Assessment and Reporting for Ischemic Heart Disease: Cardiac PET, MR, CT, and Echocardiography
View all available purchase options and get full access to this article.
https://www.jacc.org/doi/epdf/10.1016/j.jcmg.2025.08.022
2 days ago
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In the OCEAN trial, patients with successful AFib ablation at least 1 year prior, aspirin was noninferior to DOAC for stroke
www.nejm.org/doi/full/10....
#cardiosky
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Antithrombotic Therapy after Successful Catheter Ablation for Atrial Fibrillation | NEJM
Whether successful catheter ablation for atrial fibrillation eliminates the need for long-term oral anticoagulant therapy is unknown. We conducted an international, open-label, randomized, blinded-...
https://www.nejm.org/doi/full/10.1056/NEJMoa2509688
2 days ago
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Photon counting CT dramatically improves signal-to-noise ratios by directly measures x-ray photons, instead of indirect measurement of visible light photons as with traditional CT.
www.jacc.org/doi/10.1016/...
#YesCCT
#cardiosky
@jaccjournals.bsky.social
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Photon-Counting Computed Tomography in Cardiac Imaging:
View all available purchase options and get full access to this article.
https://www.jacc.org/doi/10.1016/j.jcmg.2025.07.022
3 days ago
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CRISPR-Cas9 has been used in humans to reduce non-HDL cholesterol by ~50% (also reduced HDL by ~24%)
www.nejm.org/doi/full/10....
#cardiosky
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Phase 1 Trial of CRISPR-Cas9 Gene Editing Targeting ANGPTL3 | NEJM
Angiopoietin-like protein 3 (ANGPTL3) inhibits lipoprotein and endothelial lipases. ANGPTL3 loss-of-function genetic variants are associated with decreased levels of low-density lipoprotein cholest...
https://www.nejm.org/doi/full/10.1056/NEJMoa2511778
3 days ago
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Cardiac Rehab continues to be one of the least utilized Class 1 recommendations in all of Cardiology
www.ahajournals.org/doi/10.1161/...
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American Heart Association Journals
https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.125.012067
4 days ago
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Thank you and welcome home to all who served, it is an honor to work for the Veterans Health Administration
4 days ago
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Patients are people, so are doctors. Getting to know your doctor is associated with better patient satisfaction.
www.ahajournals.org/doi/10.1161/...
#cardiosky
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Who Is That Cardiology Fellow? A Cluster Trial Examining the Impact of Cardiology Fellows' Biographical Information on Patient Perceptions of Patient‐Centered Care | Journal of the American Heart Asso...
https://www.ahajournals.org/doi/10.1161/JAHA.124.039034
5 days ago
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PCSK9i reduced MACE in primary prevention population, RRR 25%, ARR 1.8%, NNT~ 56. $239/mo on Goodrx. 4.5 yrs f/u X 12 months of tx X 56 ~ $722K to prevent one MACE.
www.nejm.org/doi/full/10....
#cardiosky
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Evolocumab in Patients without a Previous Myocardial Infarction or Stroke | NEJM
The proprotein convertase subtilisin–kexin type 9 (PCSK9) inhibitor evolocumab reduces the risk of major adverse cardiovascular events (MACE) among patients with a previous myocardial infarction, s...
https://www.nejm.org/doi/full/10.1056/NEJMoa2514428
5 days ago
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The DECAF trial, presented at AHA last week, showed that in patients with atrial fibrillation, random assignment to drinking 1 caffeinated coffee a day resulted in less AFib recurrence when compared to coffee abstinence.
jamanetwork.com/journals/jam...
@jama.com
#cardiosky
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Caffeinated Coffee Consumption or Abstinence to Reduce Atrial Fibrillation
This clinical trial compares the effect of caffeinated coffee consumption vs abstinence from coffee and caffeine on recurrent atrial fibrillation.
https://jamanetwork.com/journals/jama/fullarticle/2841253
5 days ago
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Concise clinical guidance from @ACCinTouch on the assessment and management of cardiac amyloidosis @JACCJournals @MKIttlesonMD @PanjrathG
www.jacc.org/doi/epdf/10....
#cardiosky
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Transthyretin Cardiac Amyloidosis Evaluation and Management: 2025 ACC Concise Clinical Guidance
https://www.jacc.org/doi/epdf/10.1016/j.jacc.2025.09.004
8 days ago
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"In elderly patients with NSTEMI, routine invasive strategy does not improve primary outcomes of all-cause mortality or cardiac-related death but may reduce recurrent myocardial infarction and the need for urgent revascularization."
www.jacc.org/doi/10.1016/...
@jaccjournals.bsky.social
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Routine Invasive vs Conservative Management of NSTEMI in Elderly Patients: Updated Meta-Analysis of Randomized Trials
Download article citation: If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.
https://www.jacc.org/doi/10.1016/j.jacadv.2025.102275
12 days ago
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A team from UWashington successfully removed a bullet from a patient's right ventricle, via a transfemoral approach, then closed the venotomy sire with Perclose 👀
www.jacc.org/doi/10.1016/...
@jaccjournals.bsky.social
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Percutaneous Removal of a Bullet From the Right Ventricle:
https://www.jacc.org/doi/10.1016/j.jcin.2025.09.002
12 days ago
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@accintouch.bsky.social
Provides feedback to FTC on non-compete clauses, using data from the BOG paper on the topic
www.acc.org/~/media/31EC...
#cardiosky
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https://www.acc.org/~/media/31ECAC853ED14593B28F0F4B981C5C65
13 days ago
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Physical activity improves just about everything, in latest HTN mgmt GL's, diet was #1 and exercise was #2 among 22 nonpharma strategies for BP lowering
www.jacc.org/doi/10.1016/...
www.jacc.org/doi/10.1016/...
@jaccjournals.bsky.social
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2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College o...
https://www.jacc.org/doi/10.1016/j.jacc.2025.05.007
17 days ago
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MedAxiom's Annual report on Cardiology productivity, compensation, and workforce is now available
info.medaxiom.com/2025compsurvey
@accintouch.bsky.social
#cardiosky
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2025 Comp Survey
Gain strategic insights for 2026 with our 2025 Cardiovascular Provider Compensation & Production Survey, designed exclusively for cardiology professionals.
https://info.medaxiom.com/2025compsurvey
18 days ago
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Interesting review summarizing the psychological impact that ICDs can have on patients
www.ajconline.org/article/S000...
#cardiosky
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The Psychological Impact of Implantable Cardioverter Defibrillators: A Narrative Review
Implantable cardioverter defibrillators (ICDs) are critical to the prevention of sudden cardiac death caused by life-threatening arrhythmias such as ventricular tachycardia and fibrillation. While the...
https://www.ajconline.org/article/S0002-9149(25)00399-6/fulltext
19 days ago
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Care Innovations: Introducing the OUTPACE Framework for Health Care Quality Improvement
www.ahajournals.org/doi/10.1161/...
#cardiosky
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Care Innovations: Introducing the OUTPACE Framework for Health Care Quality Improvement | Circulation: Cardiovascular Quality and Outcomes
Equitable, timely, and evidence-based care remains a central goal across health care ecosystems, yet significant quality gaps, care variability, and health disparities persist. Professional societies,...
https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.125.012211
24 days ago
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When your patient dies, thoughtful reflections from
@jaccjournals.bsky.social
s editor
@hmkyale.bsky.social
www.jacc.org/doi/10.1016/...
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When Your Patient Dies:
https://www.jacc.org/doi/10.1016/j.jacc.2025.08.057
25 days ago
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19 million non-cardiac chest CT's done annually in the US, each one an opportunity to identify and treat occult CAD
www.ahajournals.org/doi/10.1161/...
#cardiosky
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Opportunistic Detection of Coronary Artery Calcium on Noncardiac Chest Computed Tomography: An Emerging Tool for Cardiovascular Disease Prevention: A Scientific Statement From the American Heart Assoc...
Coronary artery calcium (CAC) is a marker of subclinical atherosclerosis that confers increased risk of atherosclerotic cardiovascular disease. Measured by noncontrast cardiac computed tomography, CAC...
https://www.ahajournals.org/doi/10.1161/CIR.0000000000001382
26 days ago
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The PADME cohort explores the increasing burden of CVD complications in pregnancy
#cardiosky
www.ahajournals.org/doi/10.1161/...
about 1 month ago
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A bold and exciting hypothesis in this issue of JACC from Dr. Milton Packer on how adipose tissue could be a good model for understanding HFpEF
@jaccjournals.bsky.social
www.jacc.org/doi/10.1016/...
#cardiosky
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The Adipokine Hypothesis of Heart Failure With a Preserved Ejection Fraction: A Novel Framework to Explain Pathogenesis and Guide Treatment
https://www.jacc.org/doi/10.1016/j.jacc.2025.06.055
about 1 month ago
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"The CDSS did not reduce the number of inappropriate imaging requests ordered by physicians in academic hospital settings." @JAMA_current
jamanetwork.com/journals/jam...
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Evaluation of a Clinical Decision Support System for Imaging Requests
This cluster randomized clinical trial compares the effect of implementing a clinical decision support system on the appropriateness of medical imaging ordering behavior vs no clinical decision suppor...
https://jamanetwork.com/journals/jama/fullarticle/2830127
about 1 month ago
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Thoughts from Dr. Harlan Krumholz on the ABCVM application to be an independent certifying board for cardiologists
@accintouch.bsky.social
@jaccjournals.bsky.social
www.jacc.org/doi/10.1016/...
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Rethinking Physician Certification: A Call for a Modern, Meaningful Standard
https://www.jacc.org/doi/10.1016/j.jacc.2025.09.001
about 1 month ago
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Daily IVC US was not superior to clinical assessment for adjudicating congestion (based on BNP) in hospitalized pts with acute HF
www.jacc.org/doi/10.1016/...
#cardiosky
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Inferior Vena Cava Ultrasound to Guide Decongestion in Acute Decompensated Heart Failure: A Randomized Controlled Trial
https://www.jacc.org/doi/10.1016/j.jchf.2025.102578
about 1 month ago
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@accintouch.bsky.social
and other orgs seek relief for physicians from H1B visa fees. The potential impact on health care delivery, especially in rural areas, is massive.
cardiovascularbusiness.com/topics/healt...
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Pushback against Trump's $100K visa fee continues with new lawsuit
As a new lawsuit targets the unpopular policy, the American College of Cardiology and other medical societies worry that $100,000 fees will make the ongoing physician shortage much worse.
https://cardiovascularbusiness.com/topics/healthcare-management/healthcare-staffing/pushback-against-trumps-100k-visa-fee-continues-new-lawsuit
about 1 month ago
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How does prior auth affect average patients and clinicians?
tradeoffs.org/2025/09/25/a...
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A Closer Look at a Widely Despised Health Insurance Policy
Every year, millions of people’s medical care runs into the roadblock known as prior authorization, which requires a patient’s health insurer to sign off before chemotherapy, surgery or countless othe...
https://tradeoffs.org/2025/09/25/a-closer-look-at-a-widely-despised-health-insurance-policy/
about 1 month ago
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Scammers are developing AI voice models to imitate colleagues and loved ones and asking for money
@planetmoney.bsky.social
y
www.npr.org/2025/10/08/n...
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Two ways AI is changing the business of crime (Two Indicators) : Planet Money
Pre-order the Planet Money book here for your free gift. Our sister show, The Indicator, is chronicling the evolving business of crime for its Vice Week series. Today, we bring to you two cases of cri...
https://www.npr.org/2025/10/08/nx-s1-5564762/two-ways-ai-is-changing-the-business-of-crime-two-indicators
about 1 month ago
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reposted by
David Winchester
American College of Cardiology
about 1 month ago
Heading into Legislative Conference 2025 and #ACCBOG Chair David E. Winchester, MD, MS, FACC
@drdavemd.bsky.social
#ACCBOG
opens the pre-conference sessions to a packed house. Let us know you're attending and share your highlights using
#ACCLegConf
and
#ACCAdvocacy
!
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"Exercise snacks" may be the most effective way to get inactive people to be physically active
bjsm.bmj.com/content/earl...
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Effect of exercise snacks on fitness and cardiometabolic health in physically inactive individuals: systematic review and meta-analysis
Objectives To evaluate the effects of brief bouts of exercise spread throughout the day, termed ‘exercise snacks’, on cardiorespiratory and muscular fitness, and cardiometabolic health outcomes in phy...
https://bjsm.bmj.com/content/early/2025/09/26/bjsports-2025-110027
about 1 month ago
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So much work to do on preventing heart disease
#cardiosky
@chriskramermd.bsky.social
@accintouch.bsky.social
www.jacc.org/doi/10.1016/...
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Calling All Geniuses:
https://www.jacc.org/doi/10.1016/j.jacc.2025.08.026
about 1 month ago
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"Triaging the need for routine repeat imaging is essential rather than a reflex effect in ordering TTE in uncomplicated ADHF admissions"
link.springer.com/article/10.1...
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Impact of routine repeat echocardiograms in patients hospitalized with acute decompensated heart failure without clear secondary cause - The International Journal of Cardiovascular Imaging
Transthoracic echocardiography (TTE) at the time of acute decompensated heart failure (ADHF) may reveal significant structural and hemodynamic abnormalities that can guide clinical management. However, the impact of routine repeat TTE in uncomplicated ADHF re-admissions is yet to be established. We studied patients with repeat TTE at the time of rehospitalization for ADHF to determine downstream clinical impact. In a single center retrospective study, 410 adult patients with 2 ADHF admissions within 1 year were studied. 185 patients met inclusion criteria. Demographics, key echocardiography parameters and clinical changes were collected between first and second TTE. The study population comprised predominantly of Caucasians (55.7%) and males (53%). Non-ischemic cardiomyopathy was the principal etiology of heart failure. Between first and second TTE, there were no statistically significant changes noted in left ventricular ejection fraction, right ventricular systolic pressure, right atrial pressure, E/e ratio, or diastolic function. Right ventricular function was noted to significantly worsen as seen on the second TTE (p < 0.001). Mitral and aortic regurgitation was noted to be less severe in the repeat TTE group (p = 0.030 and p = 0.047, respectively). The predominant impact of repeat TTE in rehospitalized ADHF patients was medication changes rather than significant interventions, such as advanced imaging or invasive procedures. Our study demonstrates that clinicians should focus on reserving utilization of repeat TTE in uncomplicated ADHF readmissions to those not responding to standard medical optimization including diuresis. Major effect on downstream interventions and new diagnosis is not significantly impacted by repeating TTE. Graphical abstract Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is license under a Creative Commons Attribution 3.0 Unported License.
https://link.springer.com/article/10.1007/s10554-025-03498-4
about 1 month ago
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New SciStmnt from
@accintouch.bsky.social
encourages diet and exercise optimization as well as widespread use of hsCRP and statin/colchicine as options to reduce systemic inflammation.
www.jacc.org/doi/10.1016/...
#CARDIOSKY
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Inflammation and Cardiovascular Disease: 2025 ACC Scientific Statement: A Report of the American College of Cardiology
https://www.jacc.org/doi/10.1016/j.jacc.2025.08.047
about 1 month ago
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Benevolent paternalism, "women's work", disparity in leadership opportunities, and sexual harassment are some of the ongoing challenges that women face working in academic cardiology
@accintouch.bsky.social
#WIC
#cardiosky
www.ahajournals.org/doi/10.1161/...
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Barriers and Facilitators to Women's Careers in Academic Cardiology: A Multicenter Qualitative Analysis | Journal of the American Heart Association
https://www.ahajournals.org/doi/10.1161/JAHA.125.043329
about 2 months ago
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New episode of
@accintouch.bsky.social
Practice Made Perfect is out!
www.acc.org/Latest-in-Ca...
Thanks Dr. Onderko and Dr. Bharadwaj!
#cardiosky
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ACC Practice Made Perfect: Acing the Transition: From FIT to Faculty - American College of Cardiology
https://www.acc.org/Latest-in-Cardiology/Articles/2025/09/25/14/40/PMP_26sep2025
about 2 months ago
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Prevalence of pulmonary hypertension in HF is about 50%, with some variation depending on use of echo vs. RHC and HFpEF vs HFrEF. Unfortunately, the I2 heterogeneity is almost 100%
onlinelibrary.wiley.com/doi/epdf/10....
#cardiosky
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Prevalence of Pulmonary Hypertension in Individuals With Heart Failure: A Systematic Review and Meta‐Analysis
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https://onlinelibrary.wiley.com/doi/epdf/10.1002/clc.70197
about 2 months ago
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A trio of new documents lays out methods behind
@accintouch.bsky.social
and AHA guidelines, including a $120K threshhold for QALY in the US.
@jaccjournals.bsky.social
www.jacc.org/doi/10.1016/...
www.jacc.org/doi/10.1016/...
www.jacc.org/doi/10.1016/...
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2025 ACC/AHA Clinical Practice Guidelines Core Principles and Development Process: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidel...
https://www.jacc.org/doi/10.1016/j.jacc.2025.06.013
about 2 months ago
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The Tuskegee Syphilis Experiment
@syskpodcast.bsky.social
omny.fm/shows/stuff-...
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The Tuskegee Syphilis Experiment - Stuff You Should Know
As part of our shameful history series, today we dive into the Tuskegee Syphilis Experiments of the 1930s, 40s, 50s, 60s and into the 70s.
https://omny.fm/shows/stuff-you-should-know-1/the-tuskegee-syphilis-experiment
about 2 months ago
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The
@accintouch.bsky.social
cosigned a letter from the
@ama-assn.org
to exempt physicians from the new, $100K H-1B visa application fee
searchlf.ama-assn.org/letter/docum...
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https://searchlf.ama-assn.org/letter/documentDownload?uri=%2Funstructured%2Fbinary%2Fletter%2FLETTERS%2Flfimg.zip%2FSign-on-Letter-Restriction-on-Entry-of-Certain-Nonimmigrant-Workers-Proclamation-9-25-25.pdf
about 2 months ago
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Mortality in type 1 MI is higher in the short term (<30days post discharge) and lower in the long term (>30 days)
www.ahajournals.org/doi/10.1161/...
@cianpmccarthy.bsky.social
#cardiosky
www.ahajournals.org/doi/10.1161/...
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Temporal Trends, Patient Characteristics, and Outcomes of Type 2 Versus Type 1 Myocardial Infarction Among Medicare Beneficiaries | Circulation: Cardiovascular Quality and Outcomes
BACKGROUND: Type 2 myocardial infarction (MI) is common among older adults and is associated with adverse outcomes in single-center studies. We aimed to examine temporal trends and compare outcomes be...
https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.125.012136
about 2 months ago
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Accuracy of
#AI
based measurements on echocardiography
www.jacc.org/doi/10.1016/...
#cardiosky
@jaccjournals.bsky.social
about 2 months ago
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Coffee consumption and gut microbiota
www.nature.com/articles/s41...
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Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts - Nature Microbiology
Coffee consumption is associated with the presence and abundance of a specific member of the human gut microbiome, Lawsonibacter asaccharolyticus, and changes to the plasma metabolome.
https://www.nature.com/articles/s41564-024-01858-9
about 2 months ago
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Cardiologists, please consider signing up to for the @ACCinTouch Internal Medicine and Pediatrics programs, it has been a great experience this year to serve as a mentor!
www.acc.org/About-ACC/Di...
#cardiosky
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ACC Internal Medicine and Pediatric Cardiology Programs - American College of Cardiology
ACC is dedicated to creating a strong, diverse and inclusive pipeline of future cardiovascular physicians and scientists. ACC's Internal Medicine and Pediatric Cardiology Programs are designed to intr...
https://www.acc.org/About-ACC/Diversity-and-Inclusion/ACC-Internal-Medicine-Cardiology-Programs
about 2 months ago
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The global health workforce needs more support to keep our population healthy
cardiovascularbusiness.com/topics/healt...
@chriskramermd.bsky.social
@accintouch.bsky.social
#cardiosky
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ACC: Global health workforce is in need of investment to combat noncommunicable diseases
The American College of Cardiology has committed to reducing morbidity and mortality from noncommunicable diseases by 30% by 2030, but significant investments will be needed to expand the healthcare w...
https://cardiovascularbusiness.com/topics/health-disparities/acc-global-health-workforce-need-investment-combat-noncommunicable-diseases
about 2 months ago
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Excellent review on Cardiac Amyloid Radionuclide Imaging or CARI
@asnc.bsky.social
www.journalofnuclearcardiology.org/article/S107...
#cardiosky
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How to perform and interpret cardiac amyloidosis radionuclide imaging (CARI)
Cardiac amyloidosis radionuclide imaging (CARI) has transformed the diagnostic approach to suspected transthyretin cardiomyopathy (ATTR-CM), enabling non-invasive diagnosis and reducing the need for b...
https://www.journalofnuclearcardiology.org/article/S1071-3581(25)00322-8/fulltext
about 2 months ago
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I personally welcome AI improvements of the current algorithms that attempt to pre-read ECGs
www.jacc.org/doi/10.1016/...
#cardiosky
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https://www.jacc.org/doi/10.1016/j.jacc.2025.02.008
about 2 months ago
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Most of the expansion of medical schools and residencies is occurring in sites where the "faculty" did not expect to become teachers
jamanetwork.com/journals/jam...
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The Accidental Teacher—Direct-Care Physicians Increasingly Placed in Teaching Roles
This Viewpoint discusses ways for health systems, professional societies, and academic physicians to develop and share effective teaching materials and strategies with community-based colleagues.
https://jamanetwork.com/journals/jama/fullarticle/2825798
about 2 months ago
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Great to hear Dr. Tony Bavry's voice again on this episode of
@cardionerds.bsky.social
discussing severe ASx aortic stenosis
www.cardionerds.com/427-the-appr...
#cardiosky
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320. TAVR and Stroke with Dr. Samir Kapadia
Join CardioNerds for an in-depth episode on the approach and management of asymptomatic severe aortic stenosis.
https://www.cardionerds.com/427-the-approach-to-asymptomatic-severe-aortic-stenosis-with-dr-parth-desai-and-dr-tony-bavry/
about 2 months ago
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Thanks to
@emjreviews.bsky.social
for the feature
www.emjreviews.com/cardiology/a...
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From Imaging to Advocacy: Interview with David E. Winchester
The technology that I use most frequently is coronary flow reserve combined with PET perfusion imaging and coronary artery calcium scoring...
https://www.emjreviews.com/cardiology/article/from-imaging-to-advocacy-interview-with-david-e-winchester/
2 months ago
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