If you missed seeing @colby.tuple.xyz's excellent talk back in July, you can now check out the recording 👇 youtu.be/k63Xh-oJMs0

5 Tips for Fine-Tuning Protein Language Models (PLMs) on Azure Machine Learning blog.colbyford.com/5-tips-for-f...

Our new research shows how bird flu is evolving: www.wbtv.com/video/2025/0...

quick reminder to join us tonight at @harvardmed.bsky.social for a great talk by Colby Ford @colby.tuple.xyz

H5N1 Adapts for a Human Host youtu.be/FNWdzaZCemk?... via @YouTube

New paper: #AI -Based #Antibody Design Targeting Recent #H5N1 Avian Influenza Strains www.biorxiv.org/content/10.1...

New avian #influenza (H5N1) paper: Large-scale computational modelling of H5 influenza variants against HA1-neutralising antibodies! We used #AI- and #physics-based modeling of over 18k H5N1 isolates. Paper: lnkd.in/ekikJrE9 Code: lnkd.in/eY8Y4vmt #bioinformatics #genomics #computationalbiology

New paper! Transcriptomic analyses in bioinformatics are only as good as the data we give them. In this article, we outline some best practices for QC in sequencing and bioinformatics in RNA-seq, scRNA-seq, ATAC-seq, ChIP-seq, and a ton more. Read the article: www.sciencedirect.com/science/arti...

I've created a new plugin for #PyMOL (called PyMOLfold) that allows you to fold protein sequences right in the GUI. Simply select your model of choice (e.g., #ESM3, Boltz-1) and paste in your amino acid sequence. github.com/colbyford/Py... #ai #proteinfolding #alphafold

New Paper Alert! We're very excited that our SARS-CoV-2 N <> cytokine modeling paper has been accepted in Frontiers in Bioinformatics. In this work, we showcase the use of high-performance computing for large-scale molecular modeling. Give it a read: www.frontiersin.org/articles/10....

Our consortium paper for CAGI: The Critical Assessment of Genome Interpretation was just released. Read the paper in Genome Biology here: genomebiology.biomedcentral.com/articles/10.... #bioinformatics #genomics #genetics #computationalbiology #machinelearning #ai #datascience #rarediseases

I'm very excited to present some exciting research that I've been working on. PD-1 is a very important target in cancer therapeutics, so using AI to speed up the drug discovery process is certainly of interest. AI-designed anti-PD-1 antibodies - bioRvix preprint (www.biorxiv.org/content/10.1...)

I'm very excited to share this collaborative research project that included myself and researchers from MIT Lincoln Lab where we showcased the utility of high-performance computing to scale molecular modeling in SARS-CoV-2 research. Read the preprint here: www.biorxiv.org/content/10.1...

Protein Sequence Generation with EvoDiff: colbyford.medium.com/exploring-ai... #proteins #diffusion #ai #computationalbiology #bioinformatics #rfdiffusion #alphafold #colabfold

Hello, BlueSky. ☁️

Behavioral and transcriptomic analyses of mecp2 function in zebrafish https://www.biorxiv.org/content/10.1101/2023.09.13.557635v1