Maria Felicita Gonzalez (@mariafelicita.bsky.social)

Excited to share our latest article! We find that the brain tumor Glioblastoma has a circadian clock that syncs with its host’s environment. These tumors also hijack the circadian clock and use daily signals, like glucocorticoids, to grow 🧠⏱️ @erikherzog.bsky.social More: www.cell.com/cancer-cell/...

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Daily glucocorticoids promote glioblastoma growth and circadian synchrony to the host Gonzalez-Aponte et al. identify daily glucocorticoid receptor signaling as an intrinsic driver of glioblastoma (GBM) progression and a synchronizer of tumor clock gene expression to the host. This work provides an intrinsic circadian driver, and therapeutic target, to slow GBM growth, and offers considerations for glucocorticoid use in the clinic. https://www.cell.com/cancer-cell/fulltext/S1535-6108(24)00447-1