Check out our latest publication in @NatureComms, where we show that activated muscle stem cells remodel their niche with laminin-α2, and that the loss of this process intrinsically impairs their regenerative capacity in LAMA2-related muscular dystrophy: doi.org/10.1038/s414...

We’re excited to launch our Research Highlight Series! First up: an in-depth Q&A with Dr. Daniel Ham from @ruegglab.bsky.social‬ on his latest @natcomms.nature.com‬ paper, and insights into muscle biology, research, and more. #MyoBlue Read the interview aurorascientific.com/research-hig...

In our latest preprint, we show that activated muscle stem cells secrete laminin-α2 into their niche — and that the loss of this process intrinsically impairs their regenerative capacity in LAMA2-related muscular dystrophy: doi.org/10.1101/2025...

New study by @ruegglab.bsky.social challenges previous view about the muscle growth factor #Myc! The protein is dispensable for #musclegrowth. High Myc levels disrupt muscle fiber structure & function. @unibas.ch @snsf-ch.bsky.social @naturecomms.bsky.social www.biozentrum.unibas.ch/news/detail/...

If you're using AAVs to develop a gene therapy or to study gene function in skeletal muscle, then this may be of interest to you. In our latest work, we show that AAVs commonly used to deliver transgenes to muscle fibers also target mononuclear cells: www.cell.com/molecular-th...

Check out our latest publication where we use single-nuclei RNA-seq to study gene expression at the neuromuscular junction: www.nature.com/articles/s41... The paper also characterizes three novel NMJ proteins including the transcription factor ETV4 and the MuSK-binding protein PDZRN4.