Tim Sandhu
@timsandhu.bsky.social
π€ 104
π₯ 171
π 2
computational psychiatry post doc @ cambridge
https://timothysandhu.github.io/
reposted by
Tim Sandhu
Rik Henson
6 days ago
Over the years, I have written a few Jupyter/Rmd/Matlab notebooks that attempt to teach some statistical concepts, particularly in neuroimaging. You can find them here:
www.mrc-cbu.cam.ac.uk/people/rik.h...
, though I will say a bit more about each one in a number of posts over next few days.
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People
https://www.mrc-cbu.cam.ac.uk/people/rik.henson/personal/analysis/
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Tim Sandhu
Becca Williams
about 2 months ago
βοΈNEW OPINION PIECE π¨ Want to find out how apathy might be more than evaluating cost and benefit? βοΈ Then read on! V excited for the release of my first opinion piece on
#apathy
as a failure of active inference in
@cp-trendsneuro.bsky.social
with thanks to my co-author
@cambridgeftd.bsky.social
π
add a skeleton here at some point
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Tim Sandhu
Kelly Donegan
about 2 months ago
Out now in Translational Psychiatry!
www.nature.com/articles/s41...
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Tim Sandhu
Ido Shalev
2 months ago
π§΅ New paper! Five years ago, we,
@fuzefovsky.bsky.social
, Dr Alal Eran, and I, introduced empathic disequilibrium, the mismatch between cognitive and emotional empathy. In our article published in
@cp-trendscognsci.bsky.social
, we discuss the theoretical and clinical implications of the concept.
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Empathic disequilibrium: theoretical implications and clinical relevance
Empathy is central to social cognition, yet efforts to link it with neurodiverse and clinical conditions have yielded contradictory findings, often reinforcing a deficit-focused narrative that conflic...
https://www.cell.com/trends/cognitive-sciences/fulltext/S1364-6613(25)00289-X
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I updated a blog which I wrote a few years ago about PhD applications. There's a mix of reflections and practical tips which should be useful for anyone thinking about applying for a PhD (at predominantly UK institutions). Please share if it could be helpful!
timothysandhu.github.io/blog/phd_blog/
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how to apply for PhD's | Timothy R. Sandhu
a rough guide to PhD apps
https://timothysandhu.github.io/blog/phd_blog/
2 months ago
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Tim Sandhu
Andrew MacAskill
2 months ago
Congrats to Ella for her new paper! She asked a really interesting question about how the brain represents uncertainty during hidden state inference, and in a lovely crossover with theoretical work, she shows that in mice, acetylcholine dynamics play a crucial role.
www.biorxiv.org/content/10.1...
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Acetylcholine reflects uncertainty during hidden state inference
To act adaptively, animals must infer features of the environment that cannot be observed directly, such as which option is currently rewarding, or which context they are in. These internal estimates,...
https://www.biorxiv.org/content/10.1101/2025.11.12.688036v1
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Tim Sandhu
Nazia Jassim
3 months ago
This work is now out in Nature Communications! π Computational signatures of uncertainty are reflected in motor cortex excitatory neurochemistry:
www.nature.com/articles/s41467-025-64702-6
Huge thanks to our amazing team!
@beckyneuro.bsky.social
@campsydept.bsky.social
@camneuro.bsky.social
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Long overdue update prompted by submitting my hardbound thesis: I successfully defended my PhD earlier this year and have started a postdoc with
@beckyneuro.bsky.social
! Excited for more adventures in uncertainty with an amazing team.
3 months ago
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Tim Sandhu
Sara Mehrhof
4 months ago
Mental and metabolic health are closely linked - but what drives this connection? In our new theory paper, we (w/
@camillanord.bsky.social
&
@hugofleming.bsky.social
g.bsky.social
) propose dysregulation of interoceptive energy allostasis as a key mechanism.
www.science.org/doi/10.1126/...
π§΅ 1/n
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An interoceptive model of energy allostasis linking metabolic and mental health
Interactions between metabolic interoception and regulation may drive comorbidity between mental and metabolic ill-health.
https://www.science.org/doi/10.1126/sciadv.ady4356
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Tim Sandhu
Claire O'Callaghan
5 months ago
Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level). If youβve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this:
www.cell.com/trends/cogni...
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Tim Sandhu
Camilla Nord
9 months ago
so, so excited to share our new theory which endeavours to answer why depression and poor metabolic health go hand-in-hand: "An interoceptive model of energy allostasis linking metabolic and mental health" πͺπ§ π
@saramehrhof.bsky.social
@hugofleming.bsky.social
osf.io/preprints/ps...
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OSF
https://osf.io/preprints/ps..
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