What molecular pathways connect metabolic syndrome and coronary artery disease? New research by Nuojin Wang et al. identifies ADRB2 and KDM6A as potential shared diagnostic biomarkers using integrated bioinformatics and machine learning approaches. Read the full article: doi.org/10.1530/EC-2...

Future fertility is an important consideration for boys undergoing gonadotoxic treatments in childhood. In this new review, Ferrari et al. explore current approaches to fertility preservation in prepubertal boys and the challenges of long-term management and follow-up. doi.org/10.1530/EC-2...

New study: Hans Perrild et al. provide an overview of postgraduate endocrinology training across 35 European countries, examining accreditation processes, training structures and trainee numbers. The findings may help inform future workforce planning and training standards. doi.org/10.1530/EC-2...

How does pseudohypoparathyroidism (PHP1) influence growth and weight development? Yi Yang et al. developed growth charts for underage Chinese PHP1 patients, revealing early growth plateau, short stature and earlier, more persistent weight gain in PHP-1A patients. Read here: doi.org/10.1530/EC-2...

🏆 @socendocrinology.bsky.social Member Paper Highlight Could once-daily low-dose prednisolone offer advantages over standard hydrocortisone replacement? Congratulations to Ssemmondo et al. on their paper's selection by the EiC and Deputy EiC of Endocrine Connections! doi.org/10.1530/EC-2...

Hair loss in PCOS (now called PMOS) may signal broader endocrine and metabolic dysfunction. A new review by Farzaneh Motafeghi et al. explores how insulin resistance, inflammation and genetic susceptibility contribute to androgenetic alopecia in PMOS. Read the review here: doi.org/10.1530/EC-2...

New research by Ying Ke et al: a predictive nomogram using the TyG index, fasting insulin, age & HbA1c may help estimate time to glycemic stability in hospitalised patients with type 2 diabetes receiving intensive insulin therapy. 🔗Read the full article: doi.org/10.1530/EC-2...

⏰ Last call for Editor(s)-in-Chief applications for Endocrine Connections. Applications close 31 May 2026. Help shape the future of the journal and support the global endocrinology community. Start date: 1 January 2027 Apply & learn more: ec.bioscientifica.com/page/EIC-vac...

New review by Apostolos I Gogakos et al. explores links between microplastics, nanoplastics and endocrine-disrupting chemicals and bone health. Part of the Novelties in Bone and Calcium Phosphate Disorders special collection. Read the full article here: doi.org/10.1530/EC-2...

PCOS is being renamed PMOS - Polyendocrine Metabolic Ovarian Syndrome. A global consensus reframing this complex endocrine and metabolic condition affecting 170M women worldwide. A clearer name for better diagnosis and care.

So many great conversations at #ECE2026! Thanks to everyone who’s stopped by to talk about Endocrine Connections - we’ve been delighted by the interest. Catch us on the final day tomorrow if you’re here 👋

New review article in the "Endo-ERN Vol II: Rare Diseases and Transition in Care" special collection assesses 5-year evaluation of Endo-ERN healthcare providers, focusing on on-site audits in rare endocrine care networks. By Emily K White et al. Read more: doi.org/10.1530/EC-2...

Endocrine Connections is heading to #ECE2026 in Prague! Come and join us at the European Congress of Endocrinology, hosted by our co-owning society, @esendocrinology.bsky.social, to chat all things publishing and research 👋 See you there!

How well are young people with rare endocrine conditions supported when moving to adult care? New research shows major gaps across Europe - including inconsistent transition models and limited coordination between services. Part of our joint Endo-ERN special collection. 🔗 doi.org/10.1530/EC-2...

A new study by C J de Gans examined estradiol levels and sleep in 4,754 men and women. Overall, estradiol was not clearly linked to sleep quality or timing, though those in the highest 10% reported slightly better sleep. 🔗Read the full study: doi.org/10.1530/EC-2...

New research by Andrew A. Dwyer et al. evaluates a co-designed website for congenital hypogonadotropic hypogonadism. Patients were involved at every stage, the site scored >88% on quality, and 95% would recommend it. Part of Reproductive Endocrinology 2025. 🔗 Read here: doi.org/10.1530/EC-2...

New review by Kettyuscia Coelho e Oliveira et al.: Childhood obesity may influence puberty timing in boys and girls through hormones like leptin and insulin, as well as gut microbiota. 🔗 Read the full review here: doi.org/10.1530/EC-2...

How does postpartum stress impact long-term reproductive health? New research by Gary Joseph et al. finds that a higher cortisol-to-cortisone ratio after childbirth is linked to lower AMH levels - even 10 years later. 🔗 Read the full article: doi.org/10.1530/EC-2...

Register now for the first webinar in our new series supporting the Endo-ERN Vol II: Rare Diseases and Transition in Care collection. Endo-ERN x Endocrine Connections: Genetic Testing Approaches as the Basis for Personalized Medicine 📅 10 June 2026 | 16:00–17:00 endo-ern.eu/event/placeh...

We’re proud to announce that our Q1 Editor's Choice Award goes to the article: “Elexacaftor–tezacaftor–ivacaftor enhances first-phase insulin secretion and improves glucose control in cystic fibrosis”. 🎉💙 Congratulations to the authors! Read the full article: doi.org/10.1530/EC-25-0690

April 8th is Cushing's Awareness Day 💛💙 Today we’re highlighting 3 studies exploring: - Cardiac remodelling in ACTH-dependent disease: doi.org/10.1530/EC-2... - Venous thromboembolism risk in patients: doi.org/10.1530/EC-2... - Recovery of adrenal function after surgery: doi.org/10.1530/EC-2...

"Adrenal tumour diagnostic pathway: findings from a UK national survey” by Sherwin Criseno et al., the 2nd article published in: Pearls and Pitfalls in Adrenal Malignancies. The survey highlights guideline adherence and variability in multidisciplinary practice. 🔗 doi.org/10.1530/EC-2...

🌙 First article in our Endocrine Rhythms collection is live! C.J. de Gans et al. explore how estradiol levels relate to sleep in 4,754 adults - minor links in the highest levels, but key insights for understanding hormonal cycles. Read here: doi.org/10.1530/EC-2...

📢Applications are open for Editor(s)-in-Chief of Endocrine Connections (co-Editor-in-Chief pairs welcome). Lead the journal’s strategy, peer review and global growth. ⏱️Deadline: 31 May 2026 🔗For more info: ec.bioscientifica.com/page/EIC-vac...

@esendocrinology.bsky.social Member Paper Highlight: Discontinuing rhGH at mid-puberty in adolescents with GHD did not reduce patient-reported QoL, while parents reported slightly higher well-being. Congrats to Joeri Vliegenthart et al.! 🔗 doi.org/10.1530/EC-2...

We are pleased to announce the launch of our latest special collection: Barocrinology: The Science of Obesity Medicine. Obesity is an endocrine disease. This collection covers causes, phenotypes, diagnosis & treatment. Now open for submissions! Learn more: ec.bioscientifica.com/page/barocri...

Are we underestimating hyperglycemia during chemotherapy? New research by Lukas van Baal et al. shows real-time CGM detects far more cases of steroid-induced hyperglycemia than conventional monitoring, highlighting a gap in current clinical practice. Read here: doi.org/10.1530/EC-2...

Could burosumab provide sustained benefits for adults with tumor-induced osteomalacia (TIO)? A new Phase 4 study by Ruizhi Jiajue et al. reports improved serum phosphorus, mobility, and quality of life with a favourable safety profile in Chinese patients. Read here: doi.org/10.1530/EC-2...

Research by P. B. Edström et al. establishes sex- and age-specific reference intervals for ACTH & renin in 529 healthy youths, with insights into puberty & contraceptive use. The results provide standardised SD scores to support monitoring of pediatric endocrine disorders. doi.org/10.1530/EC-2...

A new study by Elena Chertok Shacham et al. finds that adjusted ethnic differences in #dementia risk among older adults with type 2 diabetes were attenuated, while SGLT-2 and DPP-4 inhibitors were associated with lower dementia risk and mortality. Read here: doi.org/10.1530/EC-2...

Congratulations to Dr. Sandra Pereira, recipient of the 2026 Endocrine Connections Expert Reviewer Prize 🏆 Recognising exceptional commitment to high-quality peer review and research excellence at Endocrine Connections. Thank you for your dedication to the endocrine research community!

The 1st article in Pearls and Pitfalls in Adrenal Malignancies, is now live: Yanagida et al. demonstrate that CT attenuation values are highly reliable (even when measured by non-radiologists) and remain a robust tool for excluding adrenal malignancy and pheochromocytoma. doi.org/10.1530/EC-2...

A randomised controlled study by Yifan Liu et al. shows that 6 weeks of vitamin D in gestational diabetes improved oxidative stress and inflammation and was linked to lower neonatal birth weight and reduced macrosomia, with no significant change in fasting glucose. 🔗 doi.org/10.1530/EC-2...

A new case report by Lucia Digitale Selvaggio et al. links RTN4IP1 mutations with endocrine failure, expanding the known phenotype of this mitochondrial disorder. The study also considers the potential therapeutic role of coenzyme Q10. Explore the full article: doi.org/10.1530/EC-2...

Today #FEBRURAY11 we celebrate the contributions of women and girls advancing research and innovation in our field and across global scientific community. Endocrine Connections remain committed to supporting inclusive, equitable research environments - in science and in publishing. #IDWGS

New review by Michel Kabbash et al.: evidence suggests skeletal muscle is a direct target of excess PTH in primary hyperparathyroidism - affecting strength, gait, and physical function, with potential reversibility after surgery. Read the full article here: doi.org/10.1530/EC-2...

New research by Yasmine Alshammari et al. shows plasma EGF is lower in type 2 diabetes and correlates with fasting glucose, HbA1C, TG & waist-to-hip ratio, highlighting its potential as a biomarker for glycaemic control. Read the full article here: doi.org/10.1530/EC-2...

Postprandial GIP levels are inversely associated with active (HMW) adiponectin in normoglycemic women. This study by Isidora Salvatierra et al. suggests GIP may serve as an early biomarker of metabolic disturbances linked to increased adiposity, before obesity develops. 🔗 doi.org/10.1530/EC-2...

New research by Kristina Laugesen et al. shows that the Elecsys Cortisol II assay closely matches LC-MS/MS and that baseline cortisol cutoffs can be used as a fast, reliable way to screen for adrenal insufficiency. Read the full article here: doi.org/10.1530/EC-2...

New research by Bailly et al. shows that continued growth hormone therapy after final height may improve lumbar spine bone density in patients with persistent childhood-onset GHD. Read here: doi.org/10.1530/EC-2... Explore the special collection: ec.bioscientifica.com/page/bone-an...

We’re pleased to announce the first 2026 Special Collection in Endocrine Connections: Pearls and Pitfalls in Adrenal Malignancies. For more information, visit: ec.bioscientifica.com/page/adrenal...

New research from Society for Endocrinology member, Rajeev Mehta et al. shows that symptom-led tapering of physiological glucocorticoid doses promotes safe adrenal recovery, challenging current guidelines. Read the full article here: doi.org/10.1530/EC-2...

Cystic fibrosis–related diabetes affects many patients with CF. A new study by Anna Edlund et al. finds that ETI therapy enhances insulin secretion and normalises glucagon levels, offering hope for improved glucose management in this population. Read the full article here: doi.org/10.1530/EC-2...

Thyroid overactivity worsens patients' quality of life (QoL). After treatment, QoL is not completely restored for many patients. We discuss reasons, and new approaches to address long-term effects on QoL. @ncaresearchnhs.bsky.social @endoconnect.bsky.social www.researchgate.net/publication/...

How does bariatric surgery influence early metabolic markers? A new multicentre cohort study by Guna Bīlande et al. examines short-term changes in des-acyl ghrelin and their relationship with adiposity following RYGB and sleeve gastrectomy. Read the full article here: doi.org/10.1530/EC-2...

We are grateful to all of our readers, authors, reviewers, and editors for another year of impactful research in the field of endocrinology. Best wishes for 2026 from Endocrine Connections!

🎉💙 The article “Role of KNDy neurons in puberty onset in male offspring following prenatal androgen exposure” - By Runfei Ge et al. has been awarded the Q4 Editors’ Choice Award in Endocrine Connections! Read here: doi.org/10.1530/EC-2...

We would like to welcome a new Senior Editor to the Endocrine Connections Editorial Board! 🔵 Dr Nitin Kapoor, Christian Medical College, Vellore, India, joins us as Senior Editor in Obesity. Read his full bio on our website: ec.bioscientifica.com/page/edboard... Welcome to the EC team! 💙

Endocrine Connections (an open-access, peer-reviewed scientific journal covering endocrinology broadly: basic, clinical, and translational research; hormone biology; endocrine-related and intersecting disciplines) pauses activity on X (6.569 followers) Bluesky: @endoconnect.bsky.social

Ever thought about publishing with Endocrine Connections? We recently caught up with Senior Editor Professor Jun Yang at the ESA–SRB–ANZOS Meeting. She shares tips for early-career researchers, what makes a strong manuscript, and insights into the editorial process. Take a look!