More than 2 decades since GLP-1 drugs were introduced, we still don't know why people with diabetes lose about half as much weight as those without diabetes at the same dose nature.com/articles/s41...

Big randomized trial of a GLP- pill (vs placebo) achieves significant weight loss www.nejm.org/doi/full/10....

Obesity and Metabolic Syndrome: Current Insights and Future Directions. Zaiem Zarkasi, Rajshekhar N. Mudaliar, Waseem A. Majeed, and Akheel A. Syed. British Journal of Hospital Medicine www.magonlinelibrary.com/doi/full/10....

“With only one other drug, resmetirom, specifically approved for the treatment of MASH, the new approval of semaglutide, a drug from a well known and widely used class of medications for type 2 diabetes and obesity, is most welcome.” www.bmj.com/content/390/...

Type 2 diabetes: SGLT-2 inhibitors to be offered as first line treatment in major guidance “shake-up” www.bmj.com/content/390/...

Incretin-based therapies delay gastric emptying and therefore may reduce the absorption of any oral component of HRT. @annicemukherjeemd.bsky.social et al. pubmed.ncbi.nlm.nih.gov/40378270/

In this study, more than half the patients with hyperthyroidism had ≥10% peak weight gain after treatment. We need to acknowledge, recognise and manage this issue better. pubmed.ncbi.nlm.nih.gov/40238086/

annicemukherjeemd.bsky.social et al discuss considerations when prescribing incretin-based therapies in women using HRT during the menopause transition and postmenopause; and thebms.org.uk/2025/04/new-...

Aisha Awan and colleagues argue for nationally funded training programmes for the integration of displaced refugee and asylum seeking healthcare professionals @bmj.com www.bmj.com/content/388/...

A new way to measure your food intake, from your 💩 www.nature.com/articles/s42... www.nature.com/articles/s42... "proof-of-concept for detailed tracking of individual-specific, health-relevant dietary patterns without the need for questionnaires."

Thanks for sharing 🙏🏻 This review is open access and aimed at all health professionals involved in menopause care

Very comprehensive review by two top experts in the field. onlinelibrary.wiley.com/doi/10.1111/...

Obesity is the third most important predictor of heart disease. We discuss pathophysiology and management including roles of anti-obesity medications and bariatric surgery. @ncaresearchnhs.bsky.social www.sciencedirect.com/science/arti...

Accurate prediction of long-term postoperative weight loss is important for advising patients undergoing bariatric surgery. @adhithyasankar.bsky.social et al. pubmed.ncbi.nlm.nih.gov/39887840/ @ncaresearchnhs.bsky.social

How well can we predict weight loss after bariatric surgery? Our study assessed the SOPHIA weight prediction tool in our patient population. dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/...

We need to embrace multimodality approaches to the treatment of chronic obesity link.springer.com/article/10.1...

Combining GLP-1 and insulin for Type 1 diabetes: a small randomized trial showed reduced insulin need, less carbohydrate intake, better glucose regulation, and reduced body weight www.nature.com/articles/s41...

A young woman with hypertension, adrenal nodule and hypercortisolism. Adrenal Cushing syndrome, right? Read our article if you enjoy a twist in the tale, republished in the French language edition of CMAJ. pubmed.ncbi.nlm.nih.gov/39681364/

We are thrilled to join the endocrine cancer community here on Bluesky 🎉 Let’s connect! We’re a society-endorsed, #OpenAccess journal publishing research on the interplay between hormones and cancer, and related topics. Learn more 👉 eo.bioscientifica.com

We’re new to Bluesky, but not to #endocrinology. Since 1946, we’ve been dedicated to advancing endocrine science and health. We’re here to connect with researchers, clinicians, nurses and anyone interested in the vital role of #hormones in our lives.

Manchester's Bicentenary scheme is live today. Prestigious, funded PhD studentships for UK and international candidates: tinyurl.com/bdd5tffm I'm advertising an interdisciplinary project with data science & physiology colleagues Mudassar Iqbal (@miqbal13.bsky.social) & David Bechtold ⬇️ 🧪💻🧬 #PhDsky

MBS (metabolic bariatric surgery) in patients on dialysis was associated with low complication rates and significant weight loss. MBS was associated with improved survival and a higher likelihood of kidney transplantation in patients receiving dialysis. academic.oup.com/bjs/article/...

It’s Thyroid Eye Disease Awareness Week. Watch Prof Simon Pearce’s overview of this rare but potentially serious condition youtu.be/2dc3B3wlroE?... #ted #ThyroidEyeDiseaaeAwarenessWeek @simonhspearce.bsky.social

#HiSciSky #HiPhDSky 🧪🧬!! I'm a clinician scientist in Manchester, UK. I study how nuclear receptors and the circadian clock regulate energy metabolism. I'm currently advertising a funded PhD opportunity - please share! www.findaphd.com/phds/project...

Fascinating work that potentially explains yo-yo changes in weight: existence of an obesogenic memory, by way of stable epigenetic changes, in adipocytes. www.nature.com/articles/s41...

Another GLP-1 drug success. Tirzepatide in heart failure with preserved ejection fraction (HFpEF) with longer term follow-up than 2 previous trials with semaglutide nejm.org/doi/full/10.... in people with BMI >30; no data yet for HFpEF in people without obesity

Obituary: Malcolm Donaldson, paediatric endocrinologist and proud collaborator with wife Julia, author of much loved children's books including The Gruffalo. Malcolm pioneered treatment for children with growth disorders and was also a talented musician www.bmj.com/content/387/...

Not all instances of hypercortisolism associated with a unilateral adrenal adenoma are due to adrenal Cushing syndrome. Khor, Majeed & Syed. www.cmaj.ca/content/196/...

We report a significant inverse correlation between perioperative renal function and postoperative serum urate levels in people undergoing bariatric surgery for obesity. Whitehead, Mills, James, Sultan, Syed. link.springer.com/article/10.1...