Margarita Masoura
@mmasoura.bsky.social
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reposted by
Margarita Masoura
Daniel Ibrahim
3 months ago
What is a promoter? And how does it work? We very happy to share our latest work trying to understand enhancer-promoter compatibility. I am very excited about the results of
@blanka-majchrzycka.bsky.social
, which changed the way I think about promoters
www.biorxiv.org/content/10.1...
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Enhancer-promoter compatibility is mediated by the promoter-proximal region
Gene promoters induce transcription in response to distal enhancers. How enhancers specifically activate their target promoter while bypassing other promoters remains unclear. Here, we find that the p...
https://www.biorxiv.org/content/10.1101/2025.10.14.682013v1
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reposted by
Margarita Masoura
Yad Ghavi-Helm
3 months ago
Ever wondered what drives enhancer-promoter specificity? Why would an enhancer activate one gene rather than another neighboring one? Check our latest preprint, led by
@mmasoura.bsky.social
, to find out!
www.biorxiv.org/content/10.1...
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Promoter-proximal gatekeepers restrict pleiotropic enhancer inputs to achieve tissue specificity
Developmental enhancers are central regulatory elements that can activate multiple genes, yet how they selectively regulate one gene over its neighbours remains unclear. Using the Drosophila twist E3 ...
https://www.biorxiv.org/content/10.1101/2025.09.23.678065v2
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